Top 10 Best Quality Control Management Software of 2026

MasterControl is a comprehensive Quality Management System (QMS) software designed for regulated industries like life sciences, manufacturing, and medical devices. It streamlines quality processes including document control, CAPA, audits, training, complaints, and supplier management to ensure compliance with FDA, ISO, and other standards. The platform offers robust automation, real-time analytics, and seamless integration capabilities to enhance operational efficiency and reduce compliance risks.

ETQ Reliance is a cloud-based enterprise Quality Management System (QMS) that centralizes quality processes like audits, CAPA, complaints, supplier management, and document control. It excels in regulated industries by ensuring compliance with standards such as ISO 9001, FDA 21 CFR Part 11, and IATF 16949 through configurable workflows and automation. The platform's no-code tools allow organizations to adapt it to unique processes without developer involvement, supporting scalability for global operations.

Qualio is a cloud-based electronic Quality Management System (eQMS) tailored for life sciences companies, enabling streamlined management of quality processes like document control, training, CAPA, audits, non-conformances, and supplier quality. It ensures compliance with regulations such as FDA 21 CFR Part 11, ISO 13485, and EU MDR through automated workflows, electronic signatures, and audit trails. The platform promotes collaboration by integrating with tools like Jira, Slack, and Google Workspace, bridging quality and R&D teams.

Veeva QualityOne is a cloud-based Quality Management System (QMS) designed primarily for life sciences organizations, offering unified management of quality processes such as audits, CAPA, complaints, training, supplier quality, and document control. Built on Veeva's Vault platform, it ensures regulatory compliance (e.g., FDA 21 CFR Part 11, EU Annex 11) through secure, validated workflows and electronic signatures. The solution provides configurable apps and AI-driven insights to streamline operations and reduce compliance risks at enterprise scale.

ComplianceQuest is a robust Quality Management System (QMS) built natively on the Salesforce platform, offering end-to-end solutions for quality control processes including CAPA, audits, complaints, nonconformance, document control, and supplier management. It enables organizations in regulated industries to achieve compliance with standards like ISO 9001, FDA 21 CFR Part 11, and IATF 16949 through automated workflows and real-time analytics. The software integrates seamlessly with Salesforce CRM, providing a unified view of quality data alongside customer and operational insights.

AssurX is a cloud-based enterprise quality management system (eQMS) designed for regulated industries like life sciences, manufacturing, and financial services. It centralizes quality processes including complaints, CAPA, audits, training, supplier management, and change control to ensure compliance with FDA 21 CFR Part 11, ISO 13485, and other standards. The platform offers configurable workflows, automation, and real-time analytics to streamline quality event resolution and risk mitigation.

ZenQMS is a cloud-based Quality Management System (QMS) tailored for life sciences and regulated industries, offering modules for document control, CAPA, training management, audits, complaints, and supplier quality. It ensures compliance with standards like FDA 21 CFR Part 11, ISO 13485, and EU MDR through automated workflows, electronic signatures, and full audit trails. The platform emphasizes configurability and ease of deployment without heavy customization.

Plex is a cloud-native manufacturing execution system (MES) and ERP platform that includes comprehensive quality control management tools for monitoring and improving production quality. It offers features like statistical process control (SPC), inspection workflows, non-conformance management, supplier quality tracking, and automated corrective actions, all integrated with real-time shop floor data. The platform enables manufacturers to maintain compliance, reduce defects, and generate detailed quality reports seamlessly within their operations.

Arena Solutions is a cloud-based Product Lifecycle Management (PLM) platform with integrated Quality Management System (QMS) tools designed for manufacturing teams. It streamlines quality processes like CAPA, non-conformance reporting, audits, supplier management, and complaint handling while maintaining traceability to product design and BOM data. This makes it particularly effective for hardware and electronics manufacturers seeking end-to-end compliance and quality control.

Intelex is a cloud-based EHSQ (Environment, Health, Safety, and Quality) management platform that excels in quality control with modules for CAPA, audits, inspections, non-conformance management, and supplier quality. It offers a unified system to streamline compliance, risk mitigation, and continuous improvement processes across organizations. The no-code configuration allows customization without programming, supporting real-time analytics and mobile accessibility for on-the-go quality checks.