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Top 10 Best Practice Management Solutions Software of 2026

Find the top 10 best practice management solutions software to streamline your workflows. Explore now to optimize your practice.

Alexander Schmidt

Alexander Schmidt

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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In healthcare, practice management solutions software is indispensable for streamlining operations—from revenue cycle management and scheduling to patient engagement and EHR integration. With a wide spectrum of tools designed to fit practices of all sizes and specialties, choosing the right platform is critical to efficiency and care delivery; the following list highlights leading options that excel in these areas.

Quick Overview

  1. 1#1: athenaOne - Cloud-based EHR and practice management solution that automates revenue cycle management, scheduling, and patient engagement for medical practices.
  2. 2#2: AdvancedMD - Comprehensive practice management software offering scheduling, billing, EHR integration, and reporting tools for ambulatory healthcare providers.
  3. 3#3: Kareo - Billing and practice management platform designed to simplify claims processing, patient payments, and administrative workflows for independent practices.
  4. 4#4: eClinicalWorks - Integrated EHR and practice management system providing telehealth, scheduling, billing, and population health tools for various practice sizes.
  5. 5#5: NextGen Healthcare - Ambulatory practice management software with robust features for scheduling, financial management, and interoperability in specialty practices.
  6. 6#6: DrChrono - iPad-native EHR and practice management tool focused on mobile charting, billing, and patient scheduling for efficient clinic operations.
  7. 7#7: Practice Fusion - Free web-based EHR with practice management capabilities for charting, e-prescribing, scheduling, and billing in small practices.
  8. 8#8: Epic - Enterprise-grade EHR and practice management platform excelling in scalability, analytics, and seamless integration for large healthcare organizations.
  9. 9#9: SimplePractice - Practice management and telehealth solution tailored for behavioral health professionals with tools for scheduling, billing, and client notes.
  10. 10#10: CharmHealth - Cloud EHR and practice management system offering patient portal, billing, scheduling, and Meaningful Use compliance for primary care practices.

Tools were selected and ranked based on comprehensive feature sets, user-friendliness, performance reliability, and value, ensuring they address the diverse needs of modern healthcare providers.

Comparison Table

This comparison table highlights leading practice management solutions, such as athenaOne, AdvancedMD, Kareo, eClinicalWorks, NextGen Healthcare, and additional tools, offering insights to healthcare practices seeking the right fit. Readers will discover key features, usability, and practical considerations to make informed decisions aligned with their operational needs.

1athenaOne logo9.2/10

Cloud-based EHR and practice management solution that automates revenue cycle management, scheduling, and patient engagement for medical practices.

Features
9.5/10
Ease
8.4/10
Value
8.7/10
2AdvancedMD logo8.7/10

Comprehensive practice management software offering scheduling, billing, EHR integration, and reporting tools for ambulatory healthcare providers.

Features
9.3/10
Ease
7.9/10
Value
8.2/10
3Kareo logo8.6/10

Billing and practice management platform designed to simplify claims processing, patient payments, and administrative workflows for independent practices.

Features
9.0/10
Ease
8.4/10
Value
8.1/10

Integrated EHR and practice management system providing telehealth, scheduling, billing, and population health tools for various practice sizes.

Features
8.4/10
Ease
6.2/10
Value
7.3/10

Ambulatory practice management software with robust features for scheduling, financial management, and interoperability in specialty practices.

Features
8.7/10
Ease
6.8/10
Value
7.5/10
6DrChrono logo8.3/10

iPad-native EHR and practice management tool focused on mobile charting, billing, and patient scheduling for efficient clinic operations.

Features
8.8/10
Ease
7.9/10
Value
7.6/10

Free web-based EHR with practice management capabilities for charting, e-prescribing, scheduling, and billing in small practices.

Features
7.0/10
Ease
8.5/10
Value
9.2/10
8Epic logo8.7/10

Enterprise-grade EHR and practice management platform excelling in scalability, analytics, and seamless integration for large healthcare organizations.

Features
9.8/10
Ease
4.2/10
Value
6.9/10

Practice management and telehealth solution tailored for behavioral health professionals with tools for scheduling, billing, and client notes.

Features
9.2/10
Ease
8.9/10
Value
8.3/10
10CharmHealth logo8.1/10

Cloud EHR and practice management system offering patient portal, billing, scheduling, and Meaningful Use compliance for primary care practices.

Features
8.0/10
Ease
8.5/10
Value
8.3/10
1
athenaOne logo

athenaOne

enterprise

Cloud-based EHR and practice management solution that automates revenue cycle management, scheduling, and patient engagement for medical practices.

Overall Rating9.2/10
Features
9.5/10
Ease of Use
8.4/10
Value
8.7/10
Standout Feature

AI-powered Revenue Intelligence that automates denial management and predicts cash flow with over 98% claims accuracy

athenaOne by athenahealth is a comprehensive cloud-based practice management and EHR solution designed to streamline administrative workflows for healthcare practices. It offers robust features for appointment scheduling, billing, claims management, patient eligibility verification, and revenue cycle optimization. The platform integrates seamlessly with telehealth, patient engagement tools, and advanced analytics to enhance operational efficiency and financial performance.

Pros

  • Superior revenue cycle management with high clean claims rates and faster reimbursements
  • Cloud-based accessibility with strong interoperability via FHIR and real-time data exchange
  • Advanced AI-driven analytics and predictive insights for practice optimization

Cons

  • Steep learning curve for new users due to extensive feature set
  • Higher pricing compared to basic PM solutions
  • Limited customization options without additional consulting

Best For

Mid-sized to large medical practices seeking an all-in-one, scalable solution with top-tier revenue cycle performance.

Pricing

Custom subscription pricing starting at approximately $140-$400 per provider per month, plus setup fees and add-ons for advanced modules.

Visit athenaOneathenahealth.com
2
AdvancedMD logo

AdvancedMD

enterprise

Comprehensive practice management software offering scheduling, billing, EHR integration, and reporting tools for ambulatory healthcare providers.

Overall Rating8.7/10
Features
9.3/10
Ease of Use
7.9/10
Value
8.2/10
Standout Feature

Advanced Revenue Cycle Management with AI-driven predictive analytics for claims optimization and reduced denials

AdvancedMD is a comprehensive cloud-based practice management solution designed for medical practices of all sizes, offering tools for appointment scheduling, billing, claims processing, and patient eligibility verification. It integrates seamlessly with its EHR system to provide a unified platform for managing administrative workflows, revenue cycle management, and compliance reporting. The software emphasizes scalability, analytics, and interoperability with other healthcare systems to optimize practice efficiency.

Pros

  • Robust revenue cycle management with automated claims scrubbing and denial prevention
  • Scalable for solo practitioners to large multi-specialty groups
  • Strong analytics and reporting dashboards for financial and operational insights

Cons

  • Steep learning curve and complex interface for new users
  • High implementation costs and lengthy onboarding process
  • Pricing can be expensive for smaller practices without customization options

Best For

Mid-sized to large medical practices seeking an all-in-one, enterprise-grade solution with advanced billing and analytics capabilities.

Pricing

Custom subscription pricing starting at around $400-$700 per provider per month for core PM features, with add-ons for EHR and advanced modules; enterprise plans available upon request.

Visit AdvancedMDadvancedmd.com
3
Kareo logo

Kareo

enterprise

Billing and practice management platform designed to simplify claims processing, patient payments, and administrative workflows for independent practices.

Overall Rating8.6/10
Features
9.0/10
Ease of Use
8.4/10
Value
8.1/10
Standout Feature

Kareo Intelligence AI-driven claims scrubbing and denial prevention for superior reimbursement rates

Kareo is a cloud-based practice management platform tailored for independent medical practices, offering integrated tools for appointment scheduling, patient eligibility verification, billing, and claims submission. It streamlines revenue cycle management with features like automated scrubbing and denial management to improve cash flow. The software also includes patient engagement tools and reporting dashboards for operational efficiency.

Pros

  • Robust revenue cycle management with high clean claims rates
  • Intuitive cloud-based interface accessible from anywhere
  • Strong analytics and reporting for practice insights

Cons

  • Pricing can be expensive for very small practices
  • Limited advanced customization options
  • Some users report slower customer support response times

Best For

Small to mid-sized independent medical practices focused on optimizing billing and revenue without dedicated billing staff.

Pricing

Subscription-based starting at ~$140/provider/month for basic PM, up to $500+/provider/month for full RCM suite; custom quotes and pay-per-claim options available.

Visit Kareokareo.com
4
eClinicalWorks logo

eClinicalWorks

enterprise

Integrated EHR and practice management system providing telehealth, scheduling, billing, and population health tools for various practice sizes.

Overall Rating7.6/10
Features
8.4/10
Ease of Use
6.2/10
Value
7.3/10
Standout Feature

Healow Open Access patient engagement platform for seamless self-scheduling and virtual visits

eClinicalWorks is a comprehensive electronic health record (EHR) and practice management software suite designed for ambulatory healthcare practices, offering tools for appointment scheduling, billing, claims processing, and patient records management. It integrates revenue cycle management, telehealth via Healow, and advanced reporting through PRISMA analytics to streamline operations. The platform supports interoperability with labs, pharmacies, and other systems, making it suitable for multi-location practices.

Pros

  • Robust integration of EHR and practice management in one platform
  • Strong revenue cycle management and claims scrubbing tools
  • Scalable for small to large practices with mobile access via Healow app

Cons

  • Steep learning curve and outdated user interface
  • Customer support can be slow and inconsistent
  • Customization options are limited without additional fees

Best For

Medium to large ambulatory practices seeking an all-in-one EHR/PM solution with strong billing capabilities.

Pricing

Custom subscription pricing starting at around $449 per provider per month, plus one-time implementation fees and add-ons for telehealth or analytics.

Visit eClinicalWorkseclinicalworks.com
5
NextGen Healthcare logo

NextGen Healthcare

enterprise

Ambulatory practice management software with robust features for scheduling, financial management, and interoperability in specialty practices.

Overall Rating8.2/10
Features
8.7/10
Ease of Use
6.8/10
Value
7.5/10
Standout Feature

AI-powered revenue cycle analytics for predictive denial prevention and cash flow optimization

NextGen Healthcare's Practice Management (PM) solution is a robust, enterprise-grade platform designed to handle scheduling, billing, claims processing, and revenue cycle management for ambulatory practices. It integrates tightly with NextGen's EHR system, enabling unified workflows for patient registration, eligibility verification, and financial reporting. The software supports specialty practices with customizable templates and analytics for optimizing practice operations.

Pros

  • Comprehensive revenue cycle management with denial management tools
  • Strong integration with NextGen EHR and third-party systems via APIs
  • Advanced reporting and analytics for financial performance

Cons

  • Steep learning curve and complex interface for new users
  • Higher pricing that may not suit small practices
  • Occasional customer support delays reported by users

Best For

Mid-sized to large specialty practices needing scalable, integrated PM with robust billing capabilities.

Pricing

Subscription-based starting at $400-$600 per provider/month; custom enterprise quotes required.

6
DrChrono logo

DrChrono

specialized

iPad-native EHR and practice management tool focused on mobile charting, billing, and patient scheduling for efficient clinic operations.

Overall Rating8.3/10
Features
8.8/10
Ease of Use
7.9/10
Value
7.6/10
Standout Feature

Native iPad app for real-time charting and patient management directly at the point of care

DrChrono is a comprehensive cloud-based EHR and practice management software tailored for ambulatory care practices, offering integrated tools for scheduling, billing, patient records, e-prescribing, and telehealth. It emphasizes mobility with a native iOS app, enabling clinicians to chart and manage patients on iPads during visits. The platform supports customization, automation, and interoperability with labs and pharmacies to streamline workflows.

Pros

  • All-in-one EHR and practice management with strong automation
  • Superior mobile iOS app for on-the-go access
  • Robust telehealth and patient engagement tools

Cons

  • Steep learning curve for new users
  • Pricing can be high for smaller practices
  • Customer support response times vary

Best For

Small to medium-sized ambulatory practices prioritizing mobile accessibility and integrated clinical workflows.

Pricing

Custom quotes starting at ~$200/provider/month for core plans; scales with users, features, and enterprise add-ons.

Visit DrChronodrchrono.com
7
Practice Fusion logo

Practice Fusion

specialized

Free web-based EHR with practice management capabilities for charting, e-prescribing, scheduling, and billing in small practices.

Overall Rating7.4/10
Features
7.0/10
Ease of Use
8.5/10
Value
9.2/10
Standout Feature

Free, unlimited e-prescribing integrated directly into workflows

Practice Fusion is a cloud-based electronic health record (EHR) and practice management software designed for small to medium-sized medical practices, offering free core features including patient scheduling, charting, e-prescribing, and a patient portal. It streamlines administrative tasks like appointment management and generates superbills for billing, with integrations for labs and pharmacies. While not a full revenue cycle management solution, it provides essential tools for efficient practice operations at no upfront cost.

Pros

  • Completely free core platform with no subscription fees for basic use
  • Intuitive web-based interface that's quick to learn and mobile-friendly
  • Strong e-prescribing capabilities with no per-prescription charges

Cons

  • Limited customer support unless premium plans are purchased
  • Intrusive ads on the dashboard in the free version
  • Billing functionality relies on third-party integrations rather than native tools

Best For

Ideal for solo practitioners or small independent clinics seeking a cost-free, user-friendly solution for basic scheduling, patient management, and EHR integration.

Pricing

Free for core features; premium support and advanced modules start at $149/month per provider.

Visit Practice Fusionpracticefusion.com
8
Epic logo

Epic

enterprise

Enterprise-grade EHR and practice management platform excelling in scalability, analytics, and seamless integration for large healthcare organizations.

Overall Rating8.7/10
Features
9.8/10
Ease of Use
4.2/10
Value
6.9/10
Standout Feature

Care Everywhere interoperability network for secure, nationwide sharing of patient records across unaffiliated organizations

Epic is an enterprise-grade electronic health record (EHR) platform with robust integrated practice management solutions, including modules like Cadence for scheduling, Resolute for billing and revenue cycle management, and patient access tools. It streamlines administrative tasks such as appointment booking, claims processing, eligibility verification, and reporting for large healthcare organizations. The system excels in scalability and interoperability, connecting disparate systems across health networks for comprehensive practice oversight.

Pros

  • Unmatched scalability and customization for enterprise needs
  • Seamless integration with clinical EHR and interoperability via Care Everywhere
  • Advanced analytics and reporting for revenue cycle optimization

Cons

  • Steep learning curve and poor user interface intuitiveness
  • Extremely lengthy and expensive implementation (often 2-5 years)
  • Prohibitively high costs unsuitable for small practices

Best For

Large hospitals, health systems, and multi-site providers needing fully integrated EHR and practice management at scale.

Pricing

Custom enterprise licensing; typically millions annually based on modules, users, and organization size—no public pricing.

Visit Epicepic.com
9
SimplePractice logo

SimplePractice

specialized

Practice management and telehealth solution tailored for behavioral health professionals with tools for scheduling, billing, and client notes.

Overall Rating8.8/10
Features
9.2/10
Ease of Use
8.9/10
Value
8.3/10
Standout Feature

Fully integrated, HIPAA-secure telehealth with automatic session notes and billing linkage

SimplePractice is a cloud-based practice management software tailored for health and wellness professionals, including therapists, psychologists, and speech pathologists. It provides an all-in-one platform for scheduling appointments, handling insurance billing and claims, secure telehealth video sessions, electronic health records (EHR), and client communication portals. The tool automates administrative workflows to help practitioners focus on delivering care while ensuring HIPAA compliance throughout.

Pros

  • Intuitive interface with quick setup for scheduling and client intake
  • Robust insurance billing and claims management with superbills and superbills
  • HIPAA-compliant telehealth integrated seamlessly with EHR and documentation

Cons

  • Pricing escalates quickly with add-ons like per-client intake fees
  • Limited advanced customization and reporting compared to enterprise tools
  • Customer support can be slow during peak times

Best For

Solo practitioners and small mental health or wellness practices needing an integrated solution for billing, telehealth, and documentation.

Pricing

Starts at $29/user/month (Essentials, billed annually), $69 (Professional), $99 (Enterprise); plus $4-10 per new client intake and $0.30-$1.20 per claim processed.

Visit SimplePracticesimplepractice.com
10
CharmHealth logo

CharmHealth

specialized

Cloud EHR and practice management system offering patient portal, billing, scheduling, and Meaningful Use compliance for primary care practices.

Overall Rating8.1/10
Features
8.0/10
Ease of Use
8.5/10
Value
8.3/10
Standout Feature

Unlimited customizable forms and templates for tailored workflows

CharmHealth is a cloud-based all-in-one EHR and practice management software tailored for independent medical practices of all sizes. It handles key practice management functions including appointment scheduling, medical billing, claims processing, reporting, and patient engagement through a secure portal. The platform emphasizes ease of use with customizable workflows and integrates telehealth for modern care delivery.

Pros

  • Intuitive interface with minimal training required
  • Affordable all-in-one solution combining EHR and PM
  • Strong patient portal and telehealth integration

Cons

  • Limited advanced analytics and customization for large enterprises
  • Occasional performance issues with high-volume usage
  • Customer support response times can vary

Best For

Small to medium-sized independent practices seeking a cost-effective, user-friendly practice management system.

Pricing

Starts at $299/provider/month for core features; scales with add-ons like advanced billing ($399+).

Visit CharmHealthcharmhealth.com

Conclusion

The 10 tools highlighted showcase diverse strengths in streamlining practice operations, with athenaOne emerging as the top choice, excelling in cloud-based automation for revenue cycle management, scheduling, and patient engagement. AdvancedMD and Kareo rank highly, offering tailored solutions for ambulatory practices and independent workflows respectively, balancing comprehensive features and ease of use. Ultimately, the best fit depends on specific practice needs, but all provide valuable tools to enhance efficiency.

athenaOne logo
Our Top Pick
athenaOne

Take the first step toward optimizing your practice—explore athenaOne’s robust capabilities to experience seamless management of patient care and administrative tasks.