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Top 10 Best Pipette Software of 2026

Discover top 10 pipette software for precise lab tasks. Explore tools to streamline workflows—start finding the best fit now.

Gitnux Team

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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Pipette software is instrumental in enhancing lab efficiency, precision, and workflow scalability, making the choice of tool critical for modern scientific operations. This curated list spans advanced scripting platforms to user-friendly no-code solutions, ensuring there’s an option for every lab need.

Quick Overview

  1. 1#1: Tecan Maestro - Advanced software suite for designing, executing, and analyzing complex liquid handling protocols on Tecan workstations.
  2. 2#2: Hamilton Venus - Powerful scripting-based software for precise control of automated pipetting and liquid handling systems.
  3. 3#3: Beckman Biomek Method Builder - Intuitive software for building and running automated pipetting workflows on Biomek liquid handlers.
  4. 4#4: Agilent VWorks - Versatile automation software for programming pipette-based liquid handling on Bravo platforms.
  5. 5#5: Eppendorf epMotion Control - User-friendly software for controlling electronic pipetting and automated liquid handling processes.
  6. 6#6: Gilson PIPETMAX - Software for scripting and executing high-throughput pipetting applications on Gilson systems.
  7. 7#7: Dynamic Devices D360 - No-code visual programming software for liquid handling across multiple pipette robots.
  8. 8#8: Opentrons Protocol Designer - Free web-based app for creating custom pipetting protocols on affordable open-source robots.
  9. 9#9: ARTEL Pipette Tracker Pro - Advanced software for tracking, calibrating, and managing pipette performance in labs.
  10. 10#10: PerkinElmer JANUS - Integrated software for flexible pipetting and liquid handling automation workflows.

Tools were ranked based on features, compatibility with leading systems, ease of use, and overall value, prioritizing those that deliver reliable performance across diverse liquid handling applications.

Comparison Table

Discover a curated comparison of prominent pipette software tools, featuring Tecan Maestro, Hamilton Venus, Beckman Biomek Method Builder, Agilent VWorks, Eppendorf epMotion Control, and more, that streamline lab automation processes. This table provides readers with key insights into functionality, workflow design, and compatibility, enabling confident decisions for diverse科研 and clinical applications.

Advanced software suite for designing, executing, and analyzing complex liquid handling protocols on Tecan workstations.

Features
9.9/10
Ease
9.5/10
Value
9.2/10

Powerful scripting-based software for precise control of automated pipetting and liquid handling systems.

Features
9.5/10
Ease
8.4/10
Value
8.7/10

Intuitive software for building and running automated pipetting workflows on Biomek liquid handlers.

Features
9.2/10
Ease
7.8/10
Value
8.1/10

Versatile automation software for programming pipette-based liquid handling on Bravo platforms.

Features
9.2/10
Ease
7.5/10
Value
7.8/10

User-friendly software for controlling electronic pipetting and automated liquid handling processes.

Features
8.7/10
Ease
7.4/10
Value
7.6/10

Software for scripting and executing high-throughput pipetting applications on Gilson systems.

Features
7.5/10
Ease
8.0/10
Value
6.8/10

No-code visual programming software for liquid handling across multiple pipette robots.

Features
8.5/10
Ease
9.0/10
Value
7.0/10

Free web-based app for creating custom pipetting protocols on affordable open-source robots.

Features
8.6/10
Ease
9.1/10
Value
9.3/10

Advanced software for tracking, calibrating, and managing pipette performance in labs.

Features
8.7/10
Ease
7.9/10
Value
7.5/10

Integrated software for flexible pipetting and liquid handling automation workflows.

Features
8.1/10
Ease
6.4/10
Value
6.2/10
1
Tecan Maestro logo

Tecan Maestro

enterprise

Advanced software suite for designing, executing, and analyzing complex liquid handling protocols on Tecan workstations.

Overall Rating9.8/10
Features
9.9/10
Ease of Use
9.5/10
Value
9.2/10
Standout Feature

Real-time adaptive error handling and method translation from other platforms

Tecan Maestro is a state-of-the-art software platform for controlling Tecan's automated liquid handling workstations, such as Fluent and Freedom EVO. It provides an intuitive drag-and-drop interface for designing complex pipetting protocols, supports advanced scripting in C# for customization, and enables real-time monitoring, error recovery, and data analysis. With seamless integration to robotics, third-party devices, and LIMS systems, it streamlines high-throughput workflows in research and clinical labs.

Pros

  • Highly intuitive visual workflow builder for rapid protocol development
  • Robust scripting and automation capabilities with C# integration
  • Excellent scalability and integration with lab instruments and LIMS

Cons

  • High cost, typically bundled with expensive Tecan hardware
  • Advanced features have a learning curve for non-programmers
  • Primarily optimized for Tecan systems, limiting cross-platform use

Best For

High-throughput labs in pharma, biotech, and diagnostics needing precise, scalable automated pipetting.

Pricing

Custom quote required; software licenses bundled with Tecan workstations, starting at $20,000+ for enterprise setups.

2
Hamilton Venus logo

Hamilton Venus

enterprise

Powerful scripting-based software for precise control of automated pipetting and liquid handling systems.

Overall Rating9.1/10
Features
9.5/10
Ease of Use
8.4/10
Value
8.7/10
Standout Feature

Real-time method simulation and deck layout visualization for error-free protocol execution

Hamilton Venus is a robust software platform designed specifically for programming and controlling Hamilton's automated liquid handling systems, such as the STAR and ML STAR workstations. It allows users to build complex pipetting protocols using a drag-and-drop interface, VBScript-based scripting, or predefined templates for tasks like dilutions, reagent additions, and plate processing. Venus supports method simulation, error recovery, and integration with lab peripherals, making it ideal for high-precision applications in life sciences research including NGS library prep and assay automation.

Pros

  • Highly customizable scripting with VBScript and ActiveX controls for advanced users
  • Seamless integration with Hamilton hardware like CO-RE pipetting heads and grippers
  • Built-in method simulation and optimization to minimize errors and waste

Cons

  • Steep learning curve for non-programmers due to scripting reliance
  • Limited compatibility outside Hamilton ecosystems
  • Opaque pricing with dependency on hardware purchase

Best For

Research labs with Hamilton liquid handlers seeking powerful, hardware-optimized automation for reproducible high-throughput pipetting.

Pricing

Quote-based; typically bundled with Hamilton workstations (starting ~$100K+ for systems), standalone licenses available but not publicly listed.

Visit Hamilton Venushamiltoncompany.com
3
Beckman Biomek Method Builder logo

Beckman Biomek Method Builder

enterprise

Intuitive software for building and running automated pipetting workflows on Biomek liquid handlers.

Overall Rating8.7/10
Features
9.2/10
Ease of Use
7.8/10
Value
8.1/10
Standout Feature

Visual Method Builder with real-time 3D simulation and dynamic optimization for error-free protocol execution

Beckman Biomek Method Builder is a comprehensive software platform for designing, simulating, and executing automated liquid handling protocols on Beckman Coulter's Biomek FX, NX, and i-Series workstations. It features a drag-and-drop visual interface for building complex pipetting methods, supporting custom labware definitions, peripheral integrations, and real-time method optimization. The software emphasizes reproducibility with validation tools, error handling, and detailed reporting for regulated lab environments.

Pros

  • Powerful drag-and-drop method editor with simulation
  • Deep integration with Biomek hardware and accessories like Span-8 pipetting
  • Robust compliance tools for GLP/GMP labs including audit trails

Cons

  • Steep learning curve for non-expert users
  • Limited compatibility outside Beckman Coulter ecosystems
  • High cost tied to hardware ownership

Best For

High-throughput labs with Beckman Biomek workstations needing advanced, validated pipetting automation.

Pricing

Bundled with Biomek hardware (starting ~$100K+ for systems); software updates via service contracts (~$5K-$15K/year); custom licensing on request.

4
Agilent VWorks logo

Agilent VWorks

enterprise

Versatile automation software for programming pipette-based liquid handling on Bravo platforms.

Overall Rating8.4/10
Features
9.2/10
Ease of Use
7.5/10
Value
7.8/10
Standout Feature

Visual Method Editor with drag-and-drop device toolbox for intuitive, hardware-agnostic protocol building within Agilent ecosystem

Agilent VWorks is a robust software platform for controlling Agilent's automated liquid handling systems like the Bravo workstation, enabling precise pipetting, plate manipulation, and workflow automation in life sciences labs. It features a visual Method Editor for drag-and-drop protocol design, supporting complex tasks such as sample prep, NGS library construction, and high-throughput assays. The software includes simulation tools for virtual method testing and integrates seamlessly with Agilent hardware peripherals.

Pros

  • Powerful visual editor for complex multi-step protocols
  • Comprehensive simulation and debugging tools
  • Deep integration with Agilent hardware ecosystem

Cons

  • Steep learning curve for non-experts
  • Limited compatibility outside Agilent systems
  • High cost tied to proprietary hardware

Best For

Experienced lab automation teams in pharma or biotech using Agilent workstations for high-throughput pipetting.

Pricing

Bundled with hardware; software licenses start at ~$5,000/year per seat, full systems $50,000+ (quote required).

5
Eppendorf epMotion Control logo

Eppendorf epMotion Control

enterprise

User-friendly software for controlling electronic pipetting and automated liquid handling processes.

Overall Rating8.1/10
Features
8.7/10
Ease of Use
7.4/10
Value
7.6/10
Standout Feature

Advanced real-time process monitoring and error recovery during protocol execution

Eppendorf epMotion Control is the dedicated software for operating the epMotion automated liquid handling workstations, enabling precise programming of pipetting protocols for applications like PCR setup, sample prep, and genomics workflows. It features a graphical user interface for protocol design, method optimization, and execution with real-time monitoring. The software supports scripting for complex customizations and integrates seamlessly with Eppendorf's hardware ecosystem.

Pros

  • High precision automation with reliable pipetting volumes from 0.2 µL to 1 mL
  • Extensive protocol library and scripting for customization
  • Seamless integration with epMotion hardware and lab devices

Cons

  • Steep learning curve for advanced scripting
  • Proprietary and limited to Eppendorf epMotion systems
  • High upfront cost tied to expensive hardware

Best For

Mid-to-large labs needing reliable, high-throughput automated pipetting within the Eppendorf ecosystem.

Pricing

Included with epMotion workstations (starting ~$50,000–$150,000 depending on model); no standalone licensing.

6
Gilson PIPETMAX logo

Gilson PIPETMAX

enterprise

Software for scripting and executing high-throughput pipetting applications on Gilson systems.

Overall Rating7.3/10
Features
7.5/10
Ease of Use
8.0/10
Value
6.8/10
Standout Feature

Wizard-driven protocol creation with real-time 3D deck simulation for error-free setup.

Gilson PIPETMAX software is the intuitive control platform for the PIPETMAX automated pipetting workstation, enabling users to create, edit, and execute liquid handling protocols for tasks like serial dilutions, plate filling, and sample normalization. It features a graphical user interface with drag-and-drop functionality and protocol simulation to preview runs before execution. Designed for reliability in life science labs, it integrates seamlessly with Gilson pipettes and consumables for precise automation.

Pros

  • User-friendly drag-and-drop protocol builder
  • Built-in simulation mode reduces errors
  • Strong integration with Gilson hardware for accuracy

Cons

  • Limited advanced scripting compared to competitors
  • Software tied exclusively to PIPETMAX hardware
  • Higher cost for full system setup

Best For

Small to mid-sized labs needing reliable, straightforward automated pipetting without high-end customization.

Pricing

Quote-based; PIPETMAX system with software typically starts at $45,000-$65,000 depending on configuration.

7
Dynamic Devices D360 logo

Dynamic Devices D360

specialized

No-code visual programming software for liquid handling across multiple pipette robots.

Overall Rating8.0/10
Features
8.5/10
Ease of Use
9.0/10
Value
7.0/10
Standout Feature

Universal driverless compatibility with 20+ pipetting robots via visual protocol design

Dynamic Devices D360 is a no-code software platform designed for programming and controlling liquid handling robots in laboratory automation. It features a visual drag-and-drop interface for building complex pipetting protocols, simulation capabilities for testing workflows, and seamless integration with over 20 robotic platforms including Opentrons, Hamilton, and Tecan. The software optimizes lab efficiency by enabling rapid protocol development without scripting expertise.

Pros

  • Intuitive visual flowchart builder accelerates protocol creation
  • Broad hardware compatibility reduces vendor lock-in
  • Robust simulation and error-checking tools minimize runtime issues

Cons

  • Subscription pricing can be steep for small labs
  • Limited native support for highly custom scripting needs
  • Initial hardware integration may require technical setup

Best For

Mid-sized labs with diverse liquid handlers needing a user-friendly, unified automation software.

Pricing

Subscription-based; contact sales for custom quotes, typically starting at $500/month depending on features and scale.

Visit Dynamic Devices D360dynamicdevices.com
8
Opentrons Protocol Designer logo

Opentrons Protocol Designer

specialized

Free web-based app for creating custom pipetting protocols on affordable open-source robots.

Overall Rating8.4/10
Features
8.6/10
Ease of Use
9.1/10
Value
9.3/10
Standout Feature

Visual drag-and-drop builder that auto-generates executable Python code

Opentrons Protocol Designer is a free, web-based tool for designing automated pipetting protocols specifically for Opentrons liquid handling robots like the OT-2 and Flex. It offers a drag-and-drop visual interface that allows users, especially biologists without coding expertise, to build complex lab workflows involving pipetting, mixing, dispensing, and delays. Protocols can be saved, shared via a community library, or exported as Python code for further customization.

Pros

  • Intuitive no-code drag-and-drop interface for rapid protocol creation
  • Extensive community protocol library for quick starts
  • Seamless integration with Opentrons hardware and free to use

Cons

  • Limited to Opentrons robots, reducing hardware flexibility
  • Advanced customizations require switching to Python API
  • Occasional bugs in complex multi-plate protocols

Best For

Biology labs using Opentrons robots that need quick, visual protocol design without programming skills.

Pricing

Free software; requires Opentrons hardware (OT-2 starts at ~$5,000, Flex higher).

9
ARTEL Pipette Tracker Pro logo

ARTEL Pipette Tracker Pro

specialized

Advanced software for tracking, calibrating, and managing pipette performance in labs.

Overall Rating8.1/10
Features
8.7/10
Ease of Use
7.9/10
Value
7.5/10
Standout Feature

Multi-instrument data aggregation and performance trending from unlimited PCS units

ARTEL Pipette Tracker Pro is a specialized software platform for managing pipette calibration and performance data, integrating directly with ARTEL's PCS Pipette Calibration System. It enables electronic record-keeping, calibration scheduling, performance trending, and customizable reporting to ensure compliance with ISO 8655 and 21 CFR Part 11 standards. The tool supports multi-site data consolidation, audit trails, and predictive analytics for proactive pipette maintenance.

Pros

  • Seamless integration with ARTEL PCS hardware for gravimetric and photometric calibration data
  • Robust compliance features including electronic signatures and audit trails
  • Advanced trending and scheduling tools for predictive maintenance

Cons

  • Limited compatibility outside ARTEL ecosystem
  • Windows-only with moderate learning curve for advanced reporting
  • Pricing opaque without direct vendor quote

Best For

Laboratories with ARTEL PCS systems needing comprehensive, compliant pipette tracking across multiple sites.

Pricing

Custom quote required; perpetual license typically $2,500+ plus annual support, often bundled with hardware.

10
PerkinElmer JANUS logo

PerkinElmer JANUS

enterprise

Integrated software for flexible pipetting and liquid handling automation workflows.

Overall Rating7.2/10
Features
8.1/10
Ease of Use
6.4/10
Value
6.2/10
Standout Feature

Variable-span 1-8 channel pipetting head for flexible parallel processing

PerkinElmer JANUS is an automated liquid handling workstation that uses proprietary software to design, execute, and manage complex pipetting protocols in laboratory environments. The software enables precise control over multi-channel pipetting, liquid transfers, dilutions, and integrations with robotic arms and peripherals for high-throughput workflows. It supports a wide range of labware and volumes, making it suitable for genomics, proteomics, and drug discovery applications.

Pros

  • Highly precise air-displacement pipetting with low dead volumes
  • Modular hardware-software integration for scalable workflows
  • Robust protocol simulation and error-checking tools

Cons

  • Steep learning curve for non-experts
  • High upfront cost and maintenance fees
  • Limited openness for third-party integrations

Best For

Established research labs with dedicated automation specialists needing reliable high-throughput pipetting.

Pricing

Custom quote required; typically $100K+ for base system including software, with annual service contracts.

Conclusion

Evaluating a range of pipette software tools, Tecan Maestro emerges as the top choice, boasting an advanced suite for designing and analyzing complex liquid handling protocols. Hamilton Venus and Beckman Biomek Method Builder follow, with Venus offering precise scripting control and Biomek impressing with its intuitive workflow design—each a strong alternative for specific lab needs. The top tools collectively showcase innovation, flexibility, and performance, empowering labs to streamline operations effectively.

Tecan Maestro logo
Our Top Pick
Tecan Maestro

Start with Tecan Maestro to unlock its comprehensive features and elevate your liquid handling efficiency. For differing priorities, Hamilton Venus and Beckman Biomek Method Builder remain excellent options, ensuring there’s a perfect fit for every workflow.