
GITNUXSOFTWARE ADVICE
Data Science AnalyticsTop 10 Best Patient Database Software of 2026
Top 10 ranking of Patient Database Software with criteria and tradeoffs for clinics, covering Epic, Cerner, and MEDITECH.
How we ranked these tools
Core product claims cross-referenced against official documentation, changelogs, and independent technical reviews.
Analyzed video reviews and hundreds of written evaluations to capture real-world user experiences with each tool.
AI persona simulations modeled how different user types would experience each tool across common use cases and workflows.
Final rankings reviewed and approved by our editorial team with authority to override AI-generated scores based on domain expertise.
Score: Features 40% · Ease 30% · Value 30%
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Editor’s top 3 picks
Three quick recommendations before you dive into the full comparison below — each one leads on a different dimension.
Epic
Enterprise RBAC with audit log coverage for patient data access and configuration changes.
Built for fits when health systems need governed patient data and high-integrity integrations..
Cerner
Editor pickIntegration services with extensibility support schema-aware messaging and interface provisioning.
Built for fits when multi-facility programs need governed patient records with extensible integration control..
MEDITECH
Editor pickInterface-driven patient data exchange with configuration-based provisioning and schema mapping.
Built for fits when healthcare organizations need controlled patient data integration with strong governance..
Related reading
Comparison Table
This comparison table maps patient database software across integration depth, focusing on how each product connects to EHR, labs, and imaging through API and provisioning flows. It also compares each platform’s data model and schema design, plus automation and API surface for tasks like patient matching, record linking, and schema-driven workflows. Admin and governance controls are scored by RBAC granularity, audit log coverage, and configuration boundaries that affect data stewardship and throughput.
Epic
EHR suiteEpic provides electronic health record workflows with patient-centric data models, configurable integrations, and interface APIs for system-to-system exchange.
Enterprise RBAC with audit log coverage for patient data access and configuration changes.
Epic functions as the system of record for patient demographics, encounters, orders, results, and longitudinal care documentation within one governed data model. Integration depth is driven by standardized messaging, terminology alignment, and interface engines that support inbound and outbound data flows. The automation and API surface enable workflow triggers tied to clinical events, along with extensibility through configured rules and developer interfaces where permitted.
A key tradeoff is that deployments require strong governance to map local schemas, translate codes, and maintain interface contracts across connected systems. Epic fits situations where multiple departments need shared patient context and where integration throughput matters for bidirectional updates during busy clinical periods.
- +Integrated patient data model supports longitudinal records
- +Interoperability interfaces cover inbound and outbound clinical data flows
- +Automation can trigger workflows from clinical and operational events
- +RBAC and audit logging support controlled access and traceability
- –Schema mapping and code translation add upfront integration effort
- –Extensibility depends on governed configuration and approved interfaces
- –Admin governance overhead increases with added connected systems
EHR integration teams
Coordinate bidirectional patient data exchanges
Lower reconciliation work
Clinical operations leaders
Automate workflows from care events
Faster task routing
Show 2 more scenarios
Health information governance
Enforce RBAC and trace changes
Better compliance evidence
Use role-based access controls and audit trails to manage visibility into patient records.
Service line analytics teams
Build consistent reporting datasets
More reliable metrics
Use the governed data model and interface-ready schemas for stable downstream datasets.
Best for: Fits when health systems need governed patient data and high-integrity integrations.
More related reading
Cerner
EHR suiteOracle Cerner applications store patient records in integrated clinical databases and expose interoperability interfaces for data exchange and automation.
Integration services with extensibility support schema-aware messaging and interface provisioning.
Cerner fits organizations that need a patient database to act as a hub for multiple hospital systems and data domains. Integration depth is driven by its integration services, supported messaging patterns, and extensibility that maps to real clinical workflows. The data model supports structured patient entities and relationship patterns used in longitudinal records, while configuration supports schema-aware behavior across deployments. Automation and API surface support integration provisioning, event-driven updates, and controlled data access patterns using RBAC.
A tradeoff is implementation complexity, because deep schema governance and cross-system mapping require disciplined configuration and interface ownership. Cerner is a strong usage situation for multi-facility groups consolidating patient identity, clinical documentation, and downstream reporting into a single governed data layer. In that context, admin and governance controls help maintain audit log coverage and role-based permissions across integration endpoints.
- +Deep integration depth across clinical and admin data domains
- +Configurable data model and schema-aware behavior across records
- +Automation and API surface for provisioning and integration orchestration
- +RBAC and audit logging support governance across connected systems
- –Cross-system data mapping increases configuration and interface ownership effort
- –Governed schema changes require careful change management and testing
- –High integration scope can slow rollout without clear ownership boundaries
Health system integration teams
Unify patient identity across applications
Fewer mismatched records
Clinical operations leaders
Coordinate longitudinal documentation workflows
More consistent documentation timing
Show 2 more scenarios
Enterprise data governance teams
Enforce RBAC and audit coverage
Tighter compliance controls
Apply role-based access control across integration endpoints with audit log traceability.
EHR interface engineering teams
Provision interfaces with controlled throughput
Lower integration failures
Use the API and automation surface to manage interface lifecycle, validation, and event handling.
Best for: Fits when multi-facility programs need governed patient records with extensible integration control.
MEDITECH
EHR suiteMEDITECH systems manage patient records and clinical documentation with configurable interfaces for integrating patient data into other applications.
Interface-driven patient data exchange with configuration-based provisioning and schema mapping.
MEDITECH centers patient data in a structured data model that maps clinical concepts to database schema and interface payloads. Integration depth is strongest where upstream and downstream systems connect through supported interfaces for demographics, orders, results, and care documentation data. Automation and API surface are oriented toward provisioning workflows and configuration-driven integration tasks rather than ad hoc scripting. Governance controls typically rely on RBAC to restrict record-level access and on audit log style monitoring for record interactions.
A concrete tradeoff is that schema and workflow alignment can limit how quickly novel data structures fit without configuration work. MEDITECH fits organizations standardizing on a MEDITECH-oriented integration pattern for patient data exchange and internal operational workflows. It also fits environments that require controlled throughput for patient updates across multiple clinical and administrative systems while maintaining traceability.
- +Patient data model aligns with clinical workflows and interface payloads
- +Integration depth supports healthcare system provisioning and data exchange
- +RBAC limits access to patient records and functions
- +Audit-style tracking supports governance for record access and changes
- –Schema alignment can require configuration effort for nonstandard fields
- –Automation via API tends to favor defined workflows over custom orchestration
Hospital integration teams
Provision patient demographics across systems
Consistent patient records
Clinical operations leaders
Coordinate results and order workflows
Faster chart readiness
Show 2 more scenarios
Compliance and governance teams
Audit access to patient records
Better regulatory traceability
Supports controlled access with RBAC and audit-style monitoring for record interactions.
Regional health IT teams
Synchronize patient updates at scale
Lower integration drift
Handles bulk patient updates through integration interfaces with controlled throughput and configuration.
Best for: Fits when healthcare organizations need controlled patient data integration with strong governance.
Allscripts
EHR suiteAllscripts solutions manage patient data and care workflows and support integrations through interoperability interfaces and configuration options.
EHR-integrated patient record management with interoperability support for identity-linked longitudinal data.
Allscripts supports patient database use through EHR-integrated record management and identity-linked clinical data. Integration depth centers on connecting patient identity, demographics, and longitudinal clinical documents across participating systems.
Automation and API surface are oriented around interoperability, data exchange, and event-driven integration for downstream applications. Admin and governance controls focus on role-based access, auditing, and operational configuration for data handling.
- +EHR-linked patient identity reduces duplicate demography across connected systems
- +Interoperability pathways support data exchange for importing and exporting records
- +Role-based access supports governance over patient data views
- +Audit logging supports traceability for access and data events
- –Patient database behavior depends on external EHR and integration partner configuration
- –Automation depth can require custom integration work for workflow specifics
- –Extensibility varies by module and can limit consistent schema customization
- –Admin configuration often needs careful coordination across connected services
Best for: Fits when care organizations need EHR-tethered patient data with strong integration and governed access control.
athenahealth
EHR suiteathenahealth offers patient record workflows with integration connectivity and automation surfaces for extending data access and operational tasks.
athenahealth API and integration services for patient data transactions and automation workflows
athenahealth performs patient data consolidation and record operations across connected healthcare organizations and workflows. It emphasizes an enterprise patient data model with charting, demographics, encounter context, and longitudinal history that supports downstream operational processes.
Integration depth is driven by an API surface for EHR-related data exchange and automation hooks that align with administrative controls and configurable workflows. Governance relies on role-based access control patterns and audit logging to support operational accountability and controlled provisioning.
- +API-driven patient and clinical data exchange for multi-system integration
- +Extensible configuration supports workflow automation without custom app code
- +RBAC-style permissions and audit logs support controlled access and traceability
- +Centralized patient data model keeps demographics and longitudinal context aligned
- –Integration and automation require careful schema mapping to local data structures
- –Admin governance can feel complex when aligning roles across connected entities
- –Automation scope depends on available API endpoints for specific data objects
Best for: Fits when healthcare orgs need patient database integration with strong governance controls and automation.
eClinicalWorks
EHR suiteeClinicalWorks supports patient database workflows in an integrated EHR with configuration options and interoperability endpoints for connecting external systems.
Role-based access with audit logging across patient records and workflow actions.
eClinicalWorks fits healthcare organizations that need a governed patient data model tied to clinical workflows and operational operations. The system centralizes patient registration, demographics, encounters, documents, and problem lists while supporting role-based access and audit trails.
Integration depth is anchored by an API and healthcare interoperability interfaces that support data exchange with EHR, billing, lab, and referral systems. Automation is primarily driven through configurable workflows and data-driven routing rather than code-heavy customization.
- +Patient data model links demographics, encounters, documents, and clinical history
- +RBAC controls restrict access by role and workflow context
- +Audit logs track access and key record changes for governance
- +API and interoperability interfaces support EHR-adjacent system integration
- –Schema and workflow customization can require vendor or implementation support
- –Automation flexibility depends more on configuration than developer-style extensibility
- –Data exchange troubleshooting can take time when downstream schemas vary
- –Admin governance features can be complex to operate at scale
Best for: Fits when organizations need governed patient records and integration-driven automation across multiple clinical systems.
NextGen Healthcare
EHR suiteNextGen Healthcare manages patient records and clinical workflow data with integration interfaces and configuration controls for external systems.
RBAC plus audit logs for patient record governance across integrated clinical workflows.
NextGen Healthcare targets healthcare organizations that need a patient database with EHR-linked workflows and governance controls. The data model ties patient, encounter, and clinical documentation entities into a consistent schema that supports controlled views and data access boundaries.
Automation and integration rely on an API surface and configuration options that fit provisioning, RBAC, and cross-system data exchange. Admin controls include audit logging and role-based permissions that help enforce stewardship across patient records.
- +Tight EHR-linked data model for patient, encounter, and documentation records
- +RBAC supports controlled access boundaries across patient data and workflows
- +API-centric integration supports external system provisioning and data exchange
- +Audit log coverage supports traceability for record and configuration changes
- –Schema complexity can raise implementation workload for non-EHR adjacent use cases
- –Automation depends on platform configuration, which can limit low-code agility
- –API surface breadth varies by integration pattern and custom workflow needs
Best for: Fits when healthcare teams need controlled patient data with integration and automation governed by RBAC.
Practice Fusion
EHR web appPractice Fusion provided a browser-based EHR with patient database workflows and integrations, and it is used through its current operational product entry point.
Structured clinical documentation templates that standardize encounter, medication, and problem data capture.
Practice Fusion provides patient record management with structured data entry, lab and medication documentation, and care workflow support. Integration depth depends on how practice systems connect with Practice Fusion via established interfaces, export workflows, and data-sharing features.
The data model centers on charted encounters, problem lists, medications, allergies, and clinical notes with configurable templates that affect throughput. Automation and governance rely on role-based access controls, audit visibility for key actions, and admin configuration of permissions and documentation rules.
- +Chart data model covers encounters, problems, meds, allergies, and clinical notes
- +Configurable templates and structured fields support consistent documentation
- +RBAC-style permissioning helps restrict record access by role
- +Audit visibility supports tracking of key chart and account changes
- –Integration depth varies by external system and available interfaces
- –API automation surface is limited for complex provisioning workflows
- –Schema flexibility is constrained by the built-in clinical data model
- –Admin governance controls may require manual setup across multiple roles
Best for: Fits when clinics need structured charting with moderate automation and controlled access.
Nextech
EHR suiteNextech supports clinic patient workflows and patient record data models with integration capabilities for connecting systems and automating data flows.
RBAC with audit log trails for patient record access and administrative changes.
Nextech manages patient records and clinic workflows inside a configurable patient database. Integration work centers on connecting practice systems through APIs and data import capabilities, with extensibility for custom fields and schema changes.
Automation supports rule-driven tasks tied to patient and encounter data, including provisioning for users and roles. Administrative controls include audit logging and RBAC so access changes and data operations can be governed.
- +API and integration options for patient, appointment, and billing-adjacent data
- +Configurable data model with custom fields and schema adjustments for clinics
- +Rule-driven automation tied to patient and encounter record events
- +RBAC plus audit logs for access tracking and administrative governance
- –Automation logic can become complex without a clear event-to-action map
- –Deep schema customization may require disciplined change management
- –Throughput planning for bulk imports depends on pipeline configuration
- –API surface breadth for niche entities may not match all interoperability needs
Best for: Fits when mid-size clinics need governed patient data integration and workflow automation.
Greenway Health
EHR suiteGreenway Health systems store patient data and clinical documentation with interoperability interfaces that support integration and automation into external systems.
RBAC-based access controls mapped to clinical roles and patient record actions.
Greenway Health fits organizations that need a patient database backbone tightly aligned to clinical workflows and interoperability requirements. Core capabilities include patient and encounter data management, clinical documentation support, and provider-facing workflows that depend on consistent master data.
Integration depth matters through health system connectivity patterns that typically require interface mapping, data synchronization, and configuration-driven behavior. Automation and data governance rely on role-based access controls and change traceability options tied to system events.
- +Clinical record workflows tied to the patient data model
- +Interoperability supports interface mapping for external systems
- +Configuration-driven behavior for documentation and forms
- –Patient database capabilities are tightly coupled to the broader EMR workflow
- –API surface details and automation granularity are not consistently documented publicly
- –Schema customization options may be constrained by the platform data model
Best for: Fits when enterprise teams need patient data governed inside a clinical workflow stack.
How to Choose the Right Patient Database Software
This buyer's guide covers patient database software used for governed patient records, clinical documentation, and interoperability-driven integration. It references Epic, Cerner, MEDITECH, Allscripts, athenahealth, eClinicalWorks, NextGen Healthcare, Practice Fusion, Nextech, and Greenway Health.
Evaluation focuses on integration depth, data model design, automation and API surface, and admin and governance controls. The guide also translates common implementation friction like schema mapping effort and automation limits into concrete selection steps.
Patient database integration layer for governed longitudinal records
Patient database software stores patient-centric data across demographics, encounters, documents, and longitudinal history in a consistent schema. It supports interoperability interfaces for inbound and outbound exchange so connected systems can provision, synchronize, and update record data.
This tooling also enforces identity, RBAC, and audit logging so access and configuration changes tied to patient records stay traceable. Epic and Cerner illustrate this pattern with governed patient data models plus integration services and API surfaces for provisioning and schema-aware exchange.
Integration depth and governance controls for patient record data models
Patient record projects fail when the integration contract is unclear or when schema changes bypass governance. Epic and Cerner reduce that risk with interoperability interfaces plus RBAC and audit log coverage for access and configuration changes.
Automation and API surface matter because workflows need repeatable provisioning, interface-driven exchange, and event-triggered updates. MEDITECH and athenahealth focus on interface-driven exchange and API-driven transactions, while Allscripts and eClinicalWorks connect patient identity and workflow objects through EHR-integrated models.
Interoperability interface coverage with schema-aware exchange
Epic supports inbound and outbound clinical data flows through well-defined interoperability interfaces. Cerner emphasizes integration services that support schema-aware messaging and interface provisioning so connected systems can exchange data with consistent schema handling.
Patient data model that ties demographics to clinical objects
Epic centralizes clinical, administrative, and operational data into a unified model built for longitudinal records. Allscripts and eClinicalWorks link patient identity, encounters, documents, and clinical history so record identity and workflow context remain aligned across connected systems.
Automation triggers plus a documented API surface for provisioning
Epic can trigger workflows from clinical and operational events so automation can react to record activity. athenahealth provides an API surface for patient and clinical data transactions and automation hooks that align with administrative controls and configurable workflows.
Extensibility that is governed by approved configuration paths
Cerner supports extensibility through schema-aware messaging and interface provisioning within a governed environment. Epic’s extensibility depends on governed configuration and approved interfaces, which shifts customization effort into controlled patterns rather than ad hoc schema changes.
RBAC plus audit log coverage for patient access and configuration changes
Epic provides enterprise RBAC with audit log coverage for patient data access and configuration changes. Nextech and NextGen Healthcare also pair RBAC with audit log trails so access changes and administrative operations remain traceable.
Provisioning and integration orchestration support for connected workflows
Cerner and MEDITECH support interface-driven provisioning with configuration and schema mapping. MEDITECH’s interface-driven patient data exchange uses configuration-based provisioning patterns that keep record exchange tied to defined payloads and interface mappings.
Decision framework for selecting a patient database tool with controlled integration
Selection starts by matching governance requirements to RBAC and audit log coverage tied to patient data and patient-related configuration. Epic and Cerner are strong references when auditability must cover both access and configuration changes.
Next, integration depth and automation needs should map to the tool’s API surface and interface-driven provisioning behavior. athenahealth and MEDITECH fit teams that need API-driven transactions or interface-driven exchange patterns with controlled workflow automation.
Map governance scope to RBAC and audit log coverage
If patient data access and configuration changes must be traceable, Epic’s enterprise RBAC plus audit log coverage for patient data access and configuration changes is a direct match. If stewardship must cover access changes and administrative operations, Nextech and NextGen Healthcare provide RBAC paired with audit log trails for record governance.
Validate integration depth against inbound and outbound interoperability needs
For multi-system exchange across clinical data flows, Epic’s interoperability interfaces cover inbound and outbound clinical data flows. For schema-aware integration services and interface provisioning, Cerner supports schema-aware messaging patterns and governed extensibility for interface provisioning.
Confirm the data model can represent your longitudinal patient record
When demographics, encounters, and documents must stay consistent over time, Epic’s unified model supports longitudinal records. For EHR-tethered workflows where patient identity, demographics, and longitudinal documents must align, Allscripts and eClinicalWorks tie record management to identity-linked clinical data.
Check automation strategy against the API and event model
If workflows must run from clinical and operational events, Epic can trigger workflows from record activity and operational events. If automation depends on API access to patient and clinical data transactions, athenahealth emphasizes API-driven data exchange and automation hooks for provisioning workflows.
Plan for schema mapping effort and change management
If the program expects significant schema mapping and code translation, Epic and Cerner both require upfront integration effort and governed interface ownership. If nonstandard fields and schema alignment are expected, MEDITECH and eClinicalWorks can require configuration effort for schema alignment and troubleshooting when downstream schemas vary.
Choose extensibility paths that match implementation governance capacity
When customization must be controlled, Cerner’s governed environment and Epic’s extensibility through governed configuration and approved interfaces reduce uncontrolled schema drift. When clinics need custom fields and rule-driven automation, Nextech supports configurable patient data models with custom fields plus rule-driven tasks tied to patient and encounter events.
Who fits each patient database integration and governance profile
Patient database software best fits teams that must manage longitudinal patient records while connecting multiple systems through interoperability interfaces. The right choice depends on whether governance must cover access and configuration changes and whether automation must run through an API surface or through configuration-driven workflows.
Epic and Cerner match programs that prioritize high-integrity integrations with governed schema handling, while Practice Fusion targets structured charting and moderate automation for clinic workflows.
Health systems needing governed patient data and high-integrity integrations
Epic fits because it centralizes longitudinal patient data into a unified model and provides enterprise RBAC with audit log coverage for patient data access and configuration changes. Cerner also fits because it combines deep integration depth with schema-aware messaging for interface provisioning and governance.
Multi-facility programs that must control schema changes and interface ownership
Cerner fits programs that require governed schema changes with careful change management and interface ownership boundaries. MEDITECH fits when interface-driven patient data exchange and configuration-based provisioning with schema mapping are the primary integration approach.
Organizations that need API-driven patient data transactions and automation hooks
athenahealth fits because it emphasizes an API surface for patient and clinical data exchange and automation hooks aligned to configurable workflows. Nextech fits when clinics need API and data import capabilities plus rule-driven automation tied to patient and encounter events.
Clinics prioritizing EHR-tethered identity-linked record management and governed access
Allscripts fits because it connects EHR-integrated record management with identity-linked longitudinal data and audit logging. eClinicalWorks fits because it centralizes registration, encounters, documents, and problem lists with RBAC and audit trails tied to patient records and workflow actions.
Teams focused on structured charting with template-driven documentation
Practice Fusion fits clinics that need structured encounter, medication, allergy, and problem data capture via configurable templates. Governance and audit visibility still matter in this profile because it relies on RBAC-style permissions and audit visibility for key actions.
Patient data integration pitfalls tied to schema, automation, and governance
Common failures come from treating patient record integration like a generic data export project. Schema mapping effort, automation limits, and governance misalignment show up across tools when connected systems and workflow requirements are not owned clearly.
The fixes are measurable by checking interface provisioning behavior, validating audit log scope, and confirming how automation runs from events or API calls.
Underestimating schema mapping and change management work
Epic and Cerner both involve schema mapping and code translation effort, especially when connected systems require consistent schema handling. MEDITECH and eClinicalWorks can require configuration effort for schema alignment when nonstandard fields appear.
Assuming extensibility will work without governed configuration paths
Epic’s extensibility depends on governed configuration and approved interfaces, so customization outside those paths increases integration overhead. Cerner also requires governed schema changes and careful testing, so uncontrolled changes can slow rollout.
Planning automation around custom orchestration instead of available event or API endpoints
Epic supports workflow triggers from clinical and operational events, so event-based design is a better match than custom orchestration. MEDITECH and athenahealth both emphasize defined workflows and available API endpoints, so automation that depends on unsupported object coverage can stall.
Skipping RBAC and audit log scope verification for patient access and configuration
Epic provides enterprise RBAC plus audit log coverage for patient data access and configuration changes, which is the governance scope to confirm early. Greenway Health, Nextech, and NextGen Healthcare also rely on RBAC and change traceability mapped to clinical roles, so the audit scope must be validated against patient actions and record operations.
Choosing a workflow-first platform when the integration contract needs broader API automation
Greenway Health and eClinicalWorks couple patient database behavior tightly to EMR workflow and can constrain schema customization, so integration granularity may be harder to extend. Practice Fusion can also limit API automation surface for complex provisioning workflows because structured clinical documentation templates drive much of the data behavior.
How We Selected and Ranked These Tools
We evaluated Epic, Cerner, MEDITECH, Allscripts, athenahealth, eClinicalWorks, NextGen Healthcare, Practice Fusion, Nextech, and Greenway Health by scoring features, ease of use, and value, with feature depth carrying the largest impact on the overall score. Feature depth was treated as the key differentiator because patient database success depends on integration services, automation triggers, and governed extensibility rather than isolated record viewing. Ease of use and value were then applied to reflect how quickly admin teams can operate RBAC, audit logging, and interface provisioning.
Epic stands apart because enterprise RBAC with audit log coverage for patient data access and configuration changes directly supports governed traceability, and its interoperability interfaces cover inbound and outbound clinical data flows. That combination lifted Epic on both governance depth and integration throughput for connected workflows.
Frequently Asked Questions About Patient Database Software
How do Epic, Cerner, and MEDITECH differ in patient data model configuration and schema handling?
Which patient database tools provide API surfaces for provisioning and automation workflows?
What SSO and identity controls typically show up in patient database deployments?
How is RBAC enforced across patient records and workflow actions in these platforms?
What data migration patterns work best when moving patient identity and longitudinal records into a new patient database?
How do Epic, Allscripts, and eClinicalWorks handle patient identity and longitudinal documents?
Which tools support audit log coverage for both patient record access and configuration changes?
How do integrations differ when the goal is event-driven exchange versus interface-driven provisioning?
What extensibility mechanisms matter when clinics need custom fields or schema changes?
What are common implementation pitfalls when connecting patient databases to other clinical systems, and how do these tools mitigate them?
Conclusion
After evaluating 10 data science analytics, Epic stands out as our overall top pick — it scored highest across our combined criteria of features, ease of use, and value, which is why it sits at #1 in the rankings above.
Use the comparison table and detailed reviews above to validate the fit against your own requirements before committing to a tool.
Tools reviewed
Primary sources checked during evaluation.
Referenced in the comparison table and product reviews above.
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