Quick Overview
- 1#1: Kareo - Cloud-based medical billing and practice management software that automates claims processing and revenue cycle management for small to mid-sized practices.
- 2#2: AdvancedMD - Integrated EHR and medical billing platform offering end-to-end revenue cycle management with real-time eligibility checks and analytics.
- 3#3: athenahealth - Cloud-based EHR and practice management system with advanced medical billing, claims scrubbing, and payer management tools.
- 4#4: DrChrono - Mobile-first EHR and medical billing software that streamlines patient billing, claims submission, and payment posting.
- 5#5: eClinicalWorks - Comprehensive EHR solution with robust medical billing features including automated coding, claims management, and denial resolution.
- 6#6: NextGen Healthcare - Ambulatory EHR and practice management platform with powerful revenue cycle and medical billing capabilities for specialty practices.
- 7#7: Epic Systems - Enterprise EHR system featuring integrated revenue cycle management and advanced medical billing for large hospitals and health systems.
- 8#8: Oracle Health - Enterprise healthcare platform with EHR, revenue cycle management, and medical billing tools optimized for complex organizations.
- 9#9: Veradigm - Healthcare IT solutions providing EHR, practice management, and medical billing with strong interoperability and analytics.
- 10#10: Practice Fusion - Free cloud-based EHR with integrated medical billing, claims processing, and era processing for independent practices.
Tools were selected based on their ability to deliver robust features—including claims processing, coding, and denial management—alongside user experience, reliability, and value, ensuring they meet diverse practice needs.
Comparison Table
This comparison table examines popular medical billing systems software, including Kareo, AdvancedMD, athenahealth, DrChrono, eClinicalWorks, and more, to guide healthcare providers in evaluating options. Readers will gain insight into key features, integration capabilities, and usability, helping them identify the best fit for their practice’s specific needs.
| # | Tool | Category | Overall | Features | Ease of Use | Value |
|---|---|---|---|---|---|---|
| 1 | Kareo Cloud-based medical billing and practice management software that automates claims processing and revenue cycle management for small to mid-sized practices. | specialized | 9.5/10 | 9.7/10 | 9.3/10 | 9.1/10 |
| 2 | AdvancedMD Integrated EHR and medical billing platform offering end-to-end revenue cycle management with real-time eligibility checks and analytics. | specialized | 9.1/10 | 9.5/10 | 8.2/10 | 8.7/10 |
| 3 | athenahealth Cloud-based EHR and practice management system with advanced medical billing, claims scrubbing, and payer management tools. | enterprise | 8.6/10 | 9.2/10 | 7.8/10 | 8.1/10 |
| 4 | DrChrono Mobile-first EHR and medical billing software that streamlines patient billing, claims submission, and payment posting. | specialized | 8.5/10 | 9.0/10 | 7.8/10 | 7.9/10 |
| 5 | eClinicalWorks Comprehensive EHR solution with robust medical billing features including automated coding, claims management, and denial resolution. | enterprise | 7.6/10 | 8.4/10 | 6.2/10 | 7.1/10 |
| 6 | NextGen Healthcare Ambulatory EHR and practice management platform with powerful revenue cycle and medical billing capabilities for specialty practices. | enterprise | 8.4/10 | 9.1/10 | 7.6/10 | 8.0/10 |
| 7 | Epic Systems Enterprise EHR system featuring integrated revenue cycle management and advanced medical billing for large hospitals and health systems. | enterprise | 8.4/10 | 9.2/10 | 6.8/10 | 7.5/10 |
| 8 | Oracle Health Enterprise healthcare platform with EHR, revenue cycle management, and medical billing tools optimized for complex organizations. | enterprise | 8.2/10 | 9.0/10 | 7.2/10 | 7.8/10 |
| 9 | Veradigm Healthcare IT solutions providing EHR, practice management, and medical billing with strong interoperability and analytics. | enterprise | 8.1/10 | 8.7/10 | 7.2/10 | 7.8/10 |
| 10 | Practice Fusion Free cloud-based EHR with integrated medical billing, claims processing, and era processing for independent practices. | specialized | 7.1/10 | 6.5/10 | 8.2/10 | 9.3/10 |
Cloud-based medical billing and practice management software that automates claims processing and revenue cycle management for small to mid-sized practices.
Integrated EHR and medical billing platform offering end-to-end revenue cycle management with real-time eligibility checks and analytics.
Cloud-based EHR and practice management system with advanced medical billing, claims scrubbing, and payer management tools.
Mobile-first EHR and medical billing software that streamlines patient billing, claims submission, and payment posting.
Comprehensive EHR solution with robust medical billing features including automated coding, claims management, and denial resolution.
Ambulatory EHR and practice management platform with powerful revenue cycle and medical billing capabilities for specialty practices.
Enterprise EHR system featuring integrated revenue cycle management and advanced medical billing for large hospitals and health systems.
Enterprise healthcare platform with EHR, revenue cycle management, and medical billing tools optimized for complex organizations.
Healthcare IT solutions providing EHR, practice management, and medical billing with strong interoperability and analytics.
Free cloud-based EHR with integrated medical billing, claims processing, and era processing for independent practices.
Kareo
specializedCloud-based medical billing and practice management software that automates claims processing and revenue cycle management for small to mid-sized practices.
Kareo Intelligence: AI-driven analytics platform that identifies revenue leaks, predicts denials, and provides personalized optimization recommendations.
Kareo is a cloud-based medical billing and revenue cycle management platform tailored for independent healthcare practices, offering end-to-end solutions for claims processing, patient payments, and denial management. It integrates seamlessly with EHR systems to automate workflows, track reimbursements, and provide actionable analytics through Kareo Intelligence. Designed to maximize revenue and reduce administrative burdens, Kareo supports specialties like mental health, therapy, and primary care with scalable tools for practices of all sizes.
Pros
- Comprehensive revenue cycle management with automated claims scrubbing and submission for clean claims rates over 99%
- Integrated patient portal and payment processing that boosts collections by up to 30%
- Robust analytics and reporting via Kareo Intelligence for performance optimization
Cons
- Higher pricing tiers can be costly for very small solo practices
- Occasional integration challenges with niche EHR systems
- Advanced customization requires additional setup time
Best For
Small to mid-sized independent medical practices looking for an integrated, user-friendly billing solution to streamline revenue cycles and reduce denials.
Pricing
Subscription-based starting at $135 per provider/month for core billing, with tiered plans (Plus, Enterprise) up to $300+/provider/month including RCM services; custom quotes for larger practices.
AdvancedMD
specializedIntegrated EHR and medical billing platform offering end-to-end revenue cycle management with real-time eligibility checks and analytics.
AI-powered claims scrubbing and predictive denial management for superior clean claim rates
AdvancedMD is a comprehensive cloud-based medical billing software integrated within its broader EHR and practice management platform, designed to streamline revenue cycle management for healthcare providers. It automates claims submission, scrubbing, denial management, payment posting, and eligibility verification to maximize reimbursements and minimize errors. With robust analytics and reporting, it helps practices track financial performance and optimize billing workflows across specialties.
Pros
- End-to-end revenue cycle management with high first-pass claim acceptance rates
- Seamless integration with EHR and practice management
- Advanced analytics and customizable reporting for billing insights
Cons
- High cost, especially for smaller practices
- Steep learning curve and complex interface
- Customer support can be slow or inconsistent
Best For
Mid-sized to large medical practices needing a scalable, integrated billing solution with strong automation.
Pricing
Custom enterprise pricing; starts around $729/provider/month for full suite, with standalone billing options requiring quotes.
athenahealth
enterpriseCloud-based EHR and practice management system with advanced medical billing, claims scrubbing, and payer management tools.
AI-powered Revenue Intelligence for predictive denial management and reimbursement optimization
athenahealth is a cloud-based electronic health record (EHR) and practice management platform with robust medical billing capabilities, including automated claims submission, denial management, and revenue cycle optimization. It streamlines billing workflows through its athenaOne suite, integrating patient eligibility checks, payment posting, and AR management into a unified system. The software leverages AI-driven insights and real-time analytics to help practices maximize reimbursements and reduce administrative burdens.
Pros
- Comprehensive revenue cycle management with automated claims scrubbing and denial prevention
- Seamless integration with EHR and practice management for end-to-end workflows
- Advanced analytics and reporting for financial performance optimization
Cons
- High pricing with custom quotes that can be prohibitive for small practices
- Steep learning curve due to feature-rich interface
- Limited flexibility for deep customizations without vendor support
Best For
Mid-sized to large ambulatory practices and specialty groups needing integrated EHR and advanced billing automation.
Pricing
Subscription-based pricing starts at around $400-$700 per provider per month, plus one-time implementation fees and add-ons for advanced features; custom quotes required.
DrChrono
specializedMobile-first EHR and medical billing software that streamlines patient billing, claims submission, and payment posting.
Native iPad and iOS app for fully mobile charting, scheduling, and billing directly at the point of care
DrChrono is a comprehensive cloud-based EHR and practice management platform with integrated medical billing tools tailored for healthcare providers. It automates revenue cycle management, including claims scrubbing, electronic submission to payers, eligibility checks, and payment posting. The system supports specialty-specific coding (ICD-10, CPT, HCPCS) and offers real-time reporting for financial insights, making it suitable for streamlining billing workflows in medical practices.
Pros
- Seamless EHR-billing integration reduces errors and speeds up reimbursements
- Real-time eligibility verification and claims scrubbing improve clean claim rates
- Mobile app supports on-the-go billing and patient management
Cons
- Steep learning curve for non-tech-savvy users and complex setups
- Custom pricing can be expensive for solo or very small practices
- Occasional customer support delays and integration glitches reported
Best For
Small to mid-sized medical practices seeking an all-in-one EHR platform with strong billing automation.
Pricing
Custom quote-based pricing; typically starts at $200-$400 per provider per month including EHR and billing features, with add-ons for advanced RCM.
eClinicalWorks
enterpriseComprehensive EHR solution with robust medical billing features including automated coding, claims management, and denial resolution.
Intelligent revenue cycle management with AI-driven claims optimization and real-time eligibility checks
eClinicalWorks is a comprehensive electronic health records (EHR) and practice management platform with integrated medical billing features designed for healthcare providers. It streamlines revenue cycle management through automated claims submission, scrubbing, denial management, and patient payment processing. The system ensures compliance with HIPAA and supports eligibility verification, coding assistance, and detailed financial reporting directly from patient charts.
Pros
- Seamless integration between EHR, practice management, and billing for efficient workflows
- Advanced claims scrubbing and denial management tools to maximize reimbursements
- Robust reporting and analytics for financial insights and compliance
Cons
- Steep learning curve and outdated user interface that can frustrate users
- Inconsistent customer support and frequent software glitches reported
- High implementation costs and ongoing fees that strain smaller practices
Best For
Mid-to-large medical practices seeking an all-in-one EHR and billing solution with strong revenue cycle capabilities.
Pricing
Custom pricing starting at around $449 per provider per month, plus implementation fees and add-ons for advanced modules; quotes required.
NextGen Healthcare
enterpriseAmbulatory EHR and practice management platform with powerful revenue cycle and medical billing capabilities for specialty practices.
Intelligent Revenue Intelligence platform for predictive denial management and payer contract optimization
NextGen Healthcare offers a comprehensive electronic health records (EHR) and practice management platform with robust medical billing capabilities, including claims processing, denial management, and revenue cycle management (RCM). Designed for ambulatory practices, it integrates billing seamlessly with clinical workflows to improve reimbursement rates and financial performance. The software supports eligibility verification, automated scrubbing, and analytics for optimizing payer contracts.
Pros
- Seamless integration of EHR and billing for efficient workflows
- Advanced RCM tools with denial prevention and analytics
- Strong support for multi-specialty practices and interoperability
Cons
- Steep learning curve for new users
- Higher pricing compared to standalone billing solutions
- Occasional customer support delays reported
Best For
Mid-sized to large ambulatory and multi-specialty practices needing integrated EHR and advanced billing automation.
Pricing
Custom subscription pricing; typically $399-$699 per provider/month, plus implementation fees and add-ons for RCM modules.
Epic Systems
enterpriseEnterprise EHR system featuring integrated revenue cycle management and advanced medical billing for large hospitals and health systems.
Hyperspace workflow engine that unifies clinical documentation with real-time billing charge capture
Epic Systems offers a comprehensive electronic health record (EHR) platform with integrated medical billing through its Resolute Professional Billing module, automating claims submission, denial management, and revenue cycle processes. It excels in handling complex, high-volume billing for large healthcare organizations while ensuring compliance with regulations like HIPAA and ICD-10. The system's deep integration with clinical workflows minimizes errors and accelerates reimbursements.
Pros
- Seamless integration with EHR for accurate charge capture
- Advanced revenue cycle analytics and denial prevention tools
- Scalable for enterprise-level high-volume billing
Cons
- Extremely high implementation costs and timelines (often 2-3 years)
- Steep learning curve requiring extensive training
- Not cost-effective for small practices or standalone billing needs
Best For
Large hospitals and multi-facility health systems needing fully integrated EHR and billing capabilities.
Pricing
Custom enterprise pricing, typically $500K+ annually plus multi-million-dollar implementation fees.
Oracle Health
enterpriseEnterprise healthcare platform with EHR, revenue cycle management, and medical billing tools optimized for complex organizations.
AI-powered intelligent claims scrubbing and denial prediction integrated with unified patient records
Oracle Health, formerly Cerner, offers an enterprise-grade revenue cycle management (RCM) platform integrated with its electronic health records (EHR) system, automating medical billing processes from claims submission to payment collection. It handles complex billing workflows, denial management, and financial analytics using AI-driven insights and Oracle Cloud infrastructure. Ideal for large health systems, it ensures compliance with healthcare regulations like HIPAA while optimizing revenue capture across multiple facilities.
Pros
- Seamless EHR integration reduces errors and accelerates billing cycles
- Advanced AI for predictive denial management and revenue optimization
- Scalable cloud-based architecture for enterprise-level operations
Cons
- High implementation costs and long setup timelines
- Steep learning curve requiring extensive training
- Less flexible for small practices or standalone billing needs
Best For
Large hospitals and multi-facility health systems needing integrated EHR and comprehensive revenue cycle management.
Pricing
Custom enterprise pricing, typically subscription-based starting at $500K+ annually depending on scale and modules.
Veradigm
enterpriseHealthcare IT solutions providing EHR, practice management, and medical billing with strong interoperability and analytics.
AI-powered predictive denial management that proactively identifies and resolves claim issues before submission
Veradigm offers a robust revenue cycle management (RCM) platform tailored for medical billing, including automated claims submission, scrubbing, denial management, and patient payment processing. Integrated seamlessly with its electronic health record (EHR) system, it supports end-to-end financial workflows for healthcare providers of varying sizes. The software leverages advanced analytics and AI to optimize reimbursements and reduce administrative burdens.
Pros
- Comprehensive integration with EHR for streamlined workflows
- Advanced AI-driven denial prediction and prevention tools
- Scalable analytics for revenue optimization across large enterprises
Cons
- Steep learning curve for new users
- High implementation costs and customization fees
- Occasional reports of slow customer support response times
Best For
Large multi-specialty practices or health systems needing integrated EHR and billing with enterprise-scale analytics.
Pricing
Enterprise pricing via custom quote; typically starts at $500+ per provider/month, with setup fees exceeding $50,000 depending on practice size.
Practice Fusion
specializedFree cloud-based EHR with integrated medical billing, claims processing, and era processing for independent practices.
100% free EHR platform with built-in superbill generation and claims submission
Practice Fusion is a cloud-based EHR platform with integrated medical billing tools, enabling practices to generate superbills, perform eligibility checks, and submit claims through partner clearinghouses. It streamlines revenue cycle management by combining clinical documentation with billing workflows in a single interface. While not a standalone billing system, it supports HIPAA compliance, ICD-10 coding, and basic ERA posting for efficient reimbursement processes.
Pros
- Completely free core platform with no per-user fees
- Seamless integration of billing with EHR charting and scheduling
- Cloud-based access with mobile support for on-the-go billing tasks
Cons
- Limited advanced billing features like full AR management or denial analytics
- Relies heavily on third-party integrations for claims scrubbing and payments
- Occasional usability glitches and slower support response times
Best For
Small to mid-sized practices seeking a cost-free, EHR-integrated solution for basic medical billing.
Pricing
Free for core EHR and billing features; optional paid add-ons or partner integrations for advanced RCM.
Conclusion
After evaluating the top medical billing systems, Kareo leads as the top choice, with strong automation for claims processing and revenue cycle management in small to mid-sized practices. AdvancedMD and athenahealth follow closely, offering integrated EHRs and specialized features like real-time eligibility checks and advanced analytics, making them excellent alternatives depending on practice size and specific needs. All reviewed tools deliver robust solutions, but Kareo stands out for its seamless workflow and focus on operational efficiency.
Take the next step in optimizing your practice—explore Kareo’s platform to experience its streamlined billing processes and how it can elevate your revenue cycle management.
Tools Reviewed
All tools were independently evaluated for this comparison