Top 10 Best Medical Billing Practice Management Software of 2026

Kareo is a cloud-based medical billing and practice management software tailored for independent practices, offering end-to-end revenue cycle management including claims submission, denial management, and payment processing. It integrates seamlessly with EHR, scheduling, and patient engagement tools to streamline workflows and improve financial outcomes. With a focus on automation and analytics, Kareo helps practices achieve high clean claims rates and faster reimbursements.

AdvancedMD is a comprehensive cloud-based practice management and EHR platform with robust medical billing capabilities, streamlining revenue cycle management for healthcare providers. It handles electronic claims submission, scrubbing, denial management, eligibility verification, payment posting, and AR tracking through an integrated system. Ideal for specialty practices, it supports multi-location operations with real-time analytics and payer integrations to maximize reimbursements.

athenahealth is a comprehensive cloud-based platform offering integrated electronic health records (EHR), practice management, and revenue cycle management tailored for medical practices. It automates medical billing processes including claims submission, eligibility verification, denial management, and payment posting to maximize reimbursements. The software leverages AI-driven analytics and a proprietary clearinghouse network for high first-pass claim acceptance rates and operational efficiency.

DrChrono is a comprehensive cloud-based EHR and practice management platform with robust medical billing capabilities, enabling seamless claims submission, eligibility verification, payment posting, and denial management. It integrates billing workflows with scheduling, patient records, and telehealth, supporting revenue cycle management from front to back office. The platform's iOS-native apps allow providers to handle billing tasks on the go, making it suitable for modern, mobile practices.

eClinicalWorks is a comprehensive electronic health record (EHR) and practice management platform with robust medical billing features tailored for healthcare providers. It handles end-to-end revenue cycle management, including claims submission, eligibility verification, denial management, and payment posting. The software supports electronic remittance advice (ERA), automated scrubbing, and reporting tools to optimize billing efficiency across various practice sizes.

NextGen Healthcare provides a comprehensive practice management and medical billing solution integrated with its EHR platform, streamlining revenue cycle management for healthcare providers. It excels in claims processing, denial management, patient eligibility verification, automated payment posting, and detailed financial reporting. Designed primarily for ambulatory practices, it supports multiple specialties with scalable features for mid-to-large organizations.

Greenway Health offers a comprehensive practice management software suite, including its flagship Intergy platform, designed for medical billing, scheduling, and revenue cycle management in healthcare practices. It streamlines claims submission, denial management, patient payments, and compliance reporting with robust EDI capabilities and integration with EHR systems. The solution supports both cloud-based and on-premise deployments, catering to various practice sizes with a focus on specialty workflows.

CureMD is a cloud-based all-in-one platform offering electronic health records (EHR), practice management, and specialized medical billing tools tailored for healthcare providers. It automates revenue cycle management through features like electronic claims submission, real-time eligibility verification, denial management, and AR tracking. Designed for various specialties, it integrates seamlessly to reduce billing errors and accelerate reimbursements.

CollaborateMD is a cloud-based medical billing and practice management software that automates the revenue cycle for healthcare providers. It handles electronic claims submission to over 2,500 payers, patient eligibility checks, payment posting, denial management, and AR tracking. The platform also includes scheduling, reporting, and EHR integrations to streamline practice workflows and improve cash flow.

Office Ally is a web-based platform providing medical billing clearinghouse services, practice management, and EHR capabilities tailored for healthcare providers. It enables free electronic claims submission to over 4,000 payers, eligibility verification, and ERA posting, alongside scheduling, patient portals, and basic reporting. While strong on affordability, it serves as a solid entry-level solution for streamlining revenue cycle management in smaller practices.