Top 10 Best Manufacturing Quality Software of 2026

ETQ Reliance is a leading cloud-based Quality Management System (QMS) software tailored for manufacturing, enabling end-to-end management of quality processes including CAPA, audits, supplier quality, complaints, and non-conformances. Its no-code configurability allows users to adapt workflows to specific regulatory and operational needs without IT involvement. Powered by Reliance IQ AI, it provides predictive analytics and automation to proactively address quality issues, reducing risks and ensuring compliance in highly regulated environments.

MasterControl is a robust Quality Management System (QMS) software tailored for manufacturing, life sciences, and regulated industries. It offers end-to-end solutions for document control, CAPA, audit management, training, complaints, supplier management, and non-conformance tracking to ensure compliance with FDA 21 CFR Part 11, ISO 13485, and other standards. The platform automates quality processes, enhances visibility, and supports digital transformation to minimize risks and improve efficiency.

InfinityQS ProFicient is a robust statistical process control (SPC) software tailored for manufacturing quality management, enabling real-time data collection, analysis, and visualization from production processes. It supports automated monitoring of key quality metrics, predictive analytics, and compliance reporting to minimize defects and optimize operations. With seamless integration into existing manufacturing systems, it empowers teams to detect variations early and drive continuous improvement across global facilities.

Minitab is a powerful statistical software package widely used in manufacturing for quality improvement, data analysis, and process optimization. It offers specialized tools for statistical process control (SPC), measurement system analysis (MSA), design of experiments (DOE), capability studies, and regression modeling. Ideal for Six Sigma and Lean initiatives, it provides intuitive graphical outputs and wizards to simplify complex analyses without requiring programming expertise.

SAP Quality Management (QM) is a robust module within the SAP S/4HANA suite tailored for manufacturing quality control, enabling end-to-end processes from quality planning and inspections to notifications and corrective actions. It integrates seamlessly with SAP's procurement, production, and sales modules to ensure real-time quality data across the supply chain. The solution supports compliance with standards like ISO 9001 and provides advanced analytics for continuous improvement in large-scale manufacturing operations.

Oracle Quality Management Cloud is a robust enterprise solution within Oracle's Supply Chain Management suite, enabling manufacturers to plan, execute, and monitor quality processes across the production lifecycle. It handles inspections, non-conformance management, corrective actions, supplier quality assessments, and compliance with standards like ISO and FDA. Leveraging AI and analytics, it provides real-time insights and integrates seamlessly with Oracle ERP and manufacturing systems for end-to-end visibility.

Plex is a cloud-native Smart Manufacturing Platform that provides comprehensive ERP, MES, and QMS functionalities tailored for discrete and process manufacturers. Its quality management module offers real-time defect tracking, automated inspections, non-conformance reporting, SPC charts, CAPA workflows, and compliance tools for standards like IATF 16949 and ISO 9001. By integrating quality data with production, supply chain, and analytics, Plex enables proactive quality improvements and full traceability across the manufacturing lifecycle.

DELMIAworks is a comprehensive ERP platform designed for manufacturers, offering robust quality management modules integrated with production, inventory, and supply chain functions. It supports quality control through Statistical Process Control (SPC), non-conformance tracking, CAPA workflows, audits, and compliance reporting to ensure ISO standards and regulatory adherence. The software provides real-time visibility into quality metrics, enabling proactive issue resolution and continuous improvement in manufacturing operations.

Epicor Kinetic is a comprehensive ERP platform with integrated Manufacturing Quality Management modules designed for discrete, make-to-order, and process manufacturers. It supports quality planning (APQP, PPAP), inspections, non-conformance management, corrective actions (CAPA), supplier quality, and statistical process control (SPC). The system ensures compliance with standards like ISO 9001 and IATF 16949 through real-time monitoring and analytics tied to production workflows.

ComplianceQuest is a cloud-based Enterprise Quality Management System (EQMS) built natively on the Salesforce platform, tailored for manufacturing and regulated industries to streamline quality processes. It provides comprehensive modules for CAPA, audit management, nonconformance, complaints, supplier quality, document control, and training, ensuring compliance with standards like ISO 9001, IATF 16949, and FDA regulations. The software integrates quality data with CRM functionalities, enabling real-time visibility and proactive issue resolution across the organization.