Top 10 Best Manufacturing Quality Control Software of 2026

InfinityQS ProFicient is a comprehensive statistical process control (SPC) software solution tailored for manufacturing quality control, enabling real-time data collection, analysis, and visualization from production lines worldwide. It integrates seamlessly with gauges, CMMs, PLCs, MES, ERP systems, and more, providing proactive alerts, AI-driven insights, and dashboards to prevent defects and ensure compliance with standards like ISO 9001 and FDA regulations. The platform supports both on-premise and cloud deployments, scaling effortlessly for enterprises with global operations.

Minitab is a comprehensive statistical software package tailored for quality improvement and data analysis in manufacturing environments. It offers powerful tools for statistical process control (SPC), design of experiments (DOE), capability analysis, Gage R&R studies, and control charts to monitor and reduce process variation. Widely adopted in Six Sigma and Lean initiatives, Minitab enables quality professionals to make data-driven decisions for enhancing product quality and efficiency.

MasterControl is a robust enterprise quality management system (QMS) software tailored for manufacturing, life sciences, and regulated industries. It centralizes processes like document control, CAPA, non-conformance management, audits, training, and supplier management to ensure compliance with FDA, ISO, and other standards. The platform automates workflows, provides real-time analytics, and supports electronic signatures for streamlined quality control in manufacturing operations.

ETQ Reliance is a cloud-based Quality Management System (QMS) software tailored for manufacturing, automating key quality control processes such as nonconformance management, CAPA, audits, supplier quality, and inspections. It provides a no-code, configurable platform that adapts to specific manufacturing workflows without requiring custom development. The solution ensures regulatory compliance (e.g., ISO 9001, IATF 16949) and integrates with ERP systems for seamless data flow in production environments.

Plex is a cloud-based Manufacturing Execution System (MES) with integrated Quality Management capabilities, designed to streamline manufacturing processes including real-time inspections, statistical process control (SPC), and non-conformance tracking. It provides end-to-end traceability, automated audits, and compliance reporting to ensure product quality across the production lifecycle. As part of a comprehensive smart manufacturing platform, Plex connects quality data directly with ERP and production workflows for proactive issue resolution.

DELMIAworks, formerly IQMS, is a comprehensive ERP platform tailored for manufacturing with robust built-in quality control modules. It enables real-time Statistical Process Control (SPC), inspection management, non-conformance tracking, corrective and preventive actions (CAPA), and supplier quality assurance. The software integrates quality data seamlessly with production, inventory, and financials for end-to-end visibility and compliance.

Epicor Kinetic is a comprehensive cloud-based ERP platform tailored for manufacturers, featuring a robust Quality Management module that handles inspections, non-conformances, and compliance tracking. It supports statistical process control (SPC), corrective and preventive actions (CAPA), and supplier quality management within a unified system for end-to-end visibility. The software enables real-time quality monitoring and analytics to minimize defects and ensure regulatory compliance like ISO standards.

SAP Quality Management (QM) is a robust module within the SAP S/4HANA suite tailored for manufacturing quality control, enabling end-to-end processes from quality planning and inspection to control, notifications, and audits. It integrates seamlessly with SAP's ERP, production planning, and supply chain modules to provide real-time quality data, defect tracking, and compliance management. The solution supports digital inspections, stability studies, and certificate management, making it ideal for complex manufacturing environments adhering to standards like ISO and FDA.

Siemens Opcenter Quality is an enterprise-grade quality management software tailored for manufacturing, offering tools for inspection planning, real-time data collection, statistical process control (SPC), and non-conformance management. It supports digitized inspections, gauge calibration, and compliance with standards like ISO 9001 and IATF 16949. Integrated within Siemens' Digital Industries Software suite, it enables closed-loop quality processes connected to PLM, MES, and ERP systems for full traceability.

Cognex In-Sight is a machine vision software platform that powers smart cameras for automated visual inspection in manufacturing quality control. It enables defect detection, assembly verification, measurement, and part identification at high speeds on production lines. With EasyBuilder for drag-and-drop setup and advanced spreadsheet-based programming, it supports both simple and complex vision applications.