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Manufacturing Engineering

Top 10 Best Manufacturing Process Automation Software of 2026

Discover the top 10 best manufacturing process automation software to streamline operations. Explore features, compare tools, and find the perfect fit—start now!

Min-ji Park

Min-ji Park

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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Manufacturing process automation software is critical for driving efficiency, consistency, and scalability in modern production, and with a broad range of tools available—from cloud-native ERP/MES platforms to no-code workflow builders—choosing the right solution can significantly impact operational success. This curated list highlights the top tools to help manufacturers navigate their options effectively.

Quick Overview

  1. 1#1: Plex - Cloud-native ERP and MES platform that automates end-to-end manufacturing operations from shop floor to supply chain.
  2. 2#2: Epicor Kinetic - Comprehensive ERP with integrated MES for real-time manufacturing execution, quality control, and process optimization.
  3. 3#3: Siemens Opcenter - Advanced MES software for production planning, execution, quality management, and performance analytics in complex manufacturing.
  4. 4#4: SAP Digital Manufacturing - Cloud-based solution for intelligent manufacturing execution, monitoring, and orchestration across global operations.
  5. 5#5: DELMIAworks - Integrated ERP/MES system providing real-time shop floor control, inventory management, and automation for SMB manufacturers.
  6. 6#6: Rockwell Automation FactoryTalk - Industrial automation platform with MES capabilities for production management, HMI, and SCADA integration.
  7. 7#7: Infor CloudSuite Industrial - ERP solution tailored for discrete manufacturing with automation tools for quoting, scheduling, and quality assurance.
  8. 8#8: Tulip - No-code platform for building custom manufacturing apps to automate workflows, track production, and improve operator efficiency.
  9. 9#9: Ignition by Inductive Automation - Unlimited SCADA/MES platform for creating HMI, IIoT, and automation applications across manufacturing sites.
  10. 10#10: AVEVA MES - Manufacturing operations management software for real-time visibility, execution, and optimization of production processes.

Tools were selected based on a focus on robust functionality (including real-time execution, integration, and optimization), proven reliability, user-friendly design, and value across enterprise and small-to-medium manufacturing environments.

Comparison Table

In modern manufacturing, process automation software drives efficiency and innovation, making it essential for optimized operations. This comparison table explores key platforms like Plex, Epicor Kinetic, Siemens Opcenter, SAP Digital Manufacturing, DELMIAworks, and more, outlining their core features, industry focus, and unique capabilities to guide informed software selection.

1Plex logo9.8/10

Cloud-native ERP and MES platform that automates end-to-end manufacturing operations from shop floor to supply chain.

Features
9.9/10
Ease
9.4/10
Value
9.6/10

Comprehensive ERP with integrated MES for real-time manufacturing execution, quality control, and process optimization.

Features
9.2/10
Ease
7.8/10
Value
8.4/10

Advanced MES software for production planning, execution, quality management, and performance analytics in complex manufacturing.

Features
9.4/10
Ease
7.2/10
Value
8.1/10

Cloud-based solution for intelligent manufacturing execution, monitoring, and orchestration across global operations.

Features
9.2/10
Ease
7.1/10
Value
7.8/10

Integrated ERP/MES system providing real-time shop floor control, inventory management, and automation for SMB manufacturers.

Features
9.2/10
Ease
7.1/10
Value
8.0/10

Industrial automation platform with MES capabilities for production management, HMI, and SCADA integration.

Features
9.1/10
Ease
6.9/10
Value
7.6/10

ERP solution tailored for discrete manufacturing with automation tools for quoting, scheduling, and quality assurance.

Features
9.1/10
Ease
7.7/10
Value
8.2/10
8Tulip logo8.4/10

No-code platform for building custom manufacturing apps to automate workflows, track production, and improve operator efficiency.

Features
8.7/10
Ease
9.2/10
Value
7.8/10

Unlimited SCADA/MES platform for creating HMI, IIoT, and automation applications across manufacturing sites.

Features
9.5/10
Ease
7.5/10
Value
9.5/10
10AVEVA MES logo8.3/10

Manufacturing operations management software for real-time visibility, execution, and optimization of production processes.

Features
9.1/10
Ease
7.4/10
Value
8.0/10
1
Plex logo

Plex

enterprise

Cloud-native ERP and MES platform that automates end-to-end manufacturing operations from shop floor to supply chain.

Overall Rating9.8/10
Features
9.9/10
Ease of Use
9.4/10
Value
9.6/10
Standout Feature

Plex Smart Manufacturing Platform's infinite cloud scalability and zero-data-silo architecture for seamless, real-time automation across global operations

Plex is a cloud-native, smart manufacturing platform that serves as a comprehensive ERP/MES solution, automating end-to-end manufacturing processes from supply chain management to production execution and quality control. It integrates IoT devices, real-time data analytics, and AI to provide unprecedented visibility and optimization across the factory floor. Designed for modern manufacturers, Plex eliminates silos by unifying planning, execution, and compliance in a single system, enabling agile responses to market demands.

Pros

  • Fully integrated MES, ERP, QMS, and SCM in one platform
  • Real-time IoT data capture and AI-powered insights for process optimization
  • Infinite scalability with no on-premises hardware required

Cons

  • Steep initial implementation for complex operations
  • Pricing can be premium for smaller manufacturers
  • Customization options limited compared to legacy systems

Best For

Mid-to-large manufacturers seeking a unified, cloud-based platform to automate and digitize their entire production ecosystem.

Pricing

Custom quote-based subscription model, typically starting at $10,000/month for mid-sized operations, scaled by users, sites, and production volume.

Visit Plexplex.com
2
Epicor Kinetic logo

Epicor Kinetic

enterprise

Comprehensive ERP with integrated MES for real-time manufacturing execution, quality control, and process optimization.

Overall Rating8.7/10
Features
9.2/10
Ease of Use
7.8/10
Value
8.4/10
Standout Feature

Integrated MES with real-time IoT data capture and AI-powered production intelligence

Epicor Kinetic is a cloud-native ERP platform tailored for manufacturers, providing end-to-end automation of production processes, including scheduling, execution, quality control, and inventory management. It features an integrated Manufacturing Execution System (MES) that delivers real-time shop floor visibility, automated data collection, and AI-driven analytics to optimize operations. With customizable workflows and extensive IoT integrations, it enables seamless automation across the manufacturing lifecycle, reducing downtime and improving throughput.

Pros

  • Robust MES integration for real-time production monitoring and automation
  • Scalable cloud architecture with strong analytics and AI insights
  • Deep customization and industry-specific manufacturing modules

Cons

  • Complex initial setup and customization requiring expert implementation
  • Steep learning curve for non-technical users
  • Premium pricing may not suit very small manufacturers

Best For

Mid-market to enterprise manufacturers needing comprehensive ERP-driven process automation with MES capabilities.

Pricing

Subscription-based; starts at ~$175/user/month for cloud, with full implementations ranging from $100K-$500K+ annually depending on modules and scale.

3
Siemens Opcenter logo

Siemens Opcenter

enterprise

Advanced MES software for production planning, execution, quality management, and performance analytics in complex manufacturing.

Overall Rating8.7/10
Features
9.4/10
Ease of Use
7.2/10
Value
8.1/10
Standout Feature

Integrated digital twin and process simulation powered by Tecnomatix for predictive manufacturing optimization

Siemens Opcenter is a comprehensive Manufacturing Execution System (MES) and operations management suite designed to automate and optimize manufacturing processes across discrete, process, and hybrid environments. It integrates production planning, execution, quality management, performance monitoring, and advanced analytics to provide real-time visibility and control. Leveraging Siemens' Digital Enterprise platform, it connects seamlessly with PLM, ERP, and automation systems for end-to-end digitalization.

Pros

  • Robust integration with Siemens ecosystem including PLM and automation hardware
  • Advanced simulation and digital twin capabilities for process optimization
  • Scalable for global enterprises with strong analytics and AI-driven insights

Cons

  • Complex implementation requiring significant customization and expertise
  • High upfront costs and ongoing maintenance expenses
  • Steep learning curve for non-technical users

Best For

Large-scale manufacturers in complex industries like automotive, aerospace, and pharmaceuticals seeking integrated digital transformation.

Pricing

Enterprise-level pricing; quote-based, typically starting at $100,000+ annually for subscriptions or perpetual licenses with implementation fees.

4
SAP Digital Manufacturing logo

SAP Digital Manufacturing

enterprise

Cloud-based solution for intelligent manufacturing execution, monitoring, and orchestration across global operations.

Overall Rating8.5/10
Features
9.2/10
Ease of Use
7.1/10
Value
7.8/10
Standout Feature

Embedded intelligence with AI-powered component insights for real-time process optimization and predictive maintenance

SAP Digital Manufacturing is a cloud-based Manufacturing Execution System (MES) that provides end-to-end visibility and control over shop floor operations, from production planning and scheduling to execution, quality management, and maintenance. It integrates IoT devices, AI-driven analytics, and real-time data to automate and optimize manufacturing processes. Designed for enterprise-scale deployments, it seamlessly connects with SAP S/4HANA and other ERP systems for holistic supply chain management.

Pros

  • Deep integration with SAP ecosystem for seamless data flow
  • Advanced AI/ML capabilities for predictive analytics and optimization
  • Scalable for complex, global manufacturing operations

Cons

  • Complex implementation requiring significant customization
  • Steep learning curve for non-SAP users
  • High costs that may not suit smaller manufacturers

Best For

Large enterprises with existing SAP infrastructure needing robust, integrated manufacturing automation.

Pricing

Subscription-based; custom enterprise pricing typically starts at $50,000+ annually, scaling with users, modules, and deployment size.

5
DELMIAworks logo

DELMIAworks

enterprise

Integrated ERP/MES system providing real-time shop floor control, inventory management, and automation for SMB manufacturers.

Overall Rating8.4/10
Features
9.2/10
Ease of Use
7.1/10
Value
8.0/10
Standout Feature

Real-time shop floor execution system with machine integration for automated process monitoring and control

DELMIAworks is a robust ERP/MES platform tailored for manufacturing, automating key processes like production scheduling, shop floor control, inventory management, and quality assurance. It delivers real-time data insights and integrates with Dassault Systèmes' DELMIA suite for advanced digital manufacturing simulations. Ideal for discrete, repetitive, and process-based manufacturers, it streamlines operations from order to delivery with customizable workflows.

Pros

  • Deep manufacturing-specific automation including real-time MES and production intelligence
  • Scalable architecture supporting complex supply chains and multi-site operations
  • Strong integration with CAD/PLM tools for end-to-end digital thread

Cons

  • Steep learning curve due to extensive customization options
  • High implementation time and costs for full deployment
  • Pricing lacks transparency and can be expensive for smaller firms

Best For

Mid-to-large manufacturers in discrete or process industries needing integrated ERP/MES for comprehensive process automation.

Pricing

Quote-based enterprise pricing, typically $75-$150/user/month plus implementation fees starting at $50K+.

Visit DELMIAworksdelmiaworks.com
6
Rockwell Automation FactoryTalk logo

Rockwell Automation FactoryTalk

enterprise

Industrial automation platform with MES capabilities for production management, HMI, and SCADA integration.

Overall Rating8.4/10
Features
9.1/10
Ease of Use
6.9/10
Value
7.6/10
Standout Feature

FactoryTalk InnovationSuite, unifying HMI, MES, analytics, and AI-driven insights in a single cohesive platform

FactoryTalk by Rockwell Automation is a comprehensive suite of industrial automation software designed for manufacturing process control, monitoring, and optimization. It offers HMI/SCADA visualization, MES functionality, batch management, analytics, and IIoT connectivity to streamline operations from the plant floor to enterprise levels. The platform excels in real-time data collection, alarm management, and integration with Rockwell's Allen-Bradley hardware for discrete and process automation.

Pros

  • Seamless integration with Rockwell PLCs and hardware ecosystem
  • Scalable from single-machine to enterprise-wide deployments
  • Advanced analytics and predictive maintenance tools

Cons

  • Steep learning curve and complex configuration
  • High licensing and maintenance costs
  • Vendor lock-in limiting third-party hardware flexibility

Best For

Enterprise manufacturers heavily invested in Rockwell hardware seeking robust, integrated process automation and SCADA solutions.

Pricing

Quote-based pricing with perpetual licenses starting at $10,000+ per server/module, plus 20-25% annual maintenance and per-tag/client fees.

7
Infor CloudSuite Industrial logo

Infor CloudSuite Industrial

enterprise

ERP solution tailored for discrete manufacturing with automation tools for quoting, scheduling, and quality assurance.

Overall Rating8.6/10
Features
9.1/10
Ease of Use
7.7/10
Value
8.2/10
Standout Feature

Integrated Advanced Planning and Scheduling (APS) with real-time MES for dynamic shop floor automation

Infor CloudSuite Industrial is a comprehensive cloud-based ERP platform tailored for industrial machinery and equipment manufacturers, providing advanced manufacturing process automation through its integrated MES capabilities. It enables real-time shop floor control, production scheduling, quality management, and inventory optimization to streamline discrete manufacturing operations. The solution supports Industry 4.0 technologies like IoT integration and predictive analytics for enhanced automation and efficiency.

Pros

  • Industry-specific automation for engineer-to-order and make-to-order processes
  • Robust MES with real-time visibility and IoT connectivity
  • Scalable cloud deployment with strong integration via Infor OS

Cons

  • Complex implementation requiring significant customization
  • Steep learning curve for non-expert users
  • Higher cost structure suited for enterprises only

Best For

Mid-to-large industrial manufacturers needing end-to-end ERP with deep process automation for complex production environments.

Pricing

Quote-based subscription pricing, typically $150-$300 per user/month depending on modules and scale, with implementation fees.

8
Tulip logo

Tulip

specialized

No-code platform for building custom manufacturing apps to automate workflows, track production, and improve operator efficiency.

Overall Rating8.4/10
Features
8.7/10
Ease of Use
9.2/10
Value
7.8/10
Standout Feature

Stations-based no-code app builder that runs interactive workflows directly on shop floor edge devices

Tulip (tulip.co) is a no-code platform designed for manufacturing process automation, enabling users to build custom frontline apps for shop floor operations like production tracking, quality inspections, and maintenance workflows. It connects to PLCs, sensors, and enterprise systems to capture real-time data, driving digital transformation without requiring developers. The platform emphasizes edge computing and stations-based apps that empower operators to automate processes intuitively.

Pros

  • Intuitive no-code app builder accelerates deployment of custom manufacturing apps
  • Robust integrations with hardware (PLCs, IoT) and software (MES, ERP) for real-time data flow
  • Advanced analytics and tables provide actionable insights for process optimization

Cons

  • Pricing can be steep for small-scale manufacturers or pilots
  • Advanced customizations may still require manufacturing domain expertise
  • Less comprehensive out-of-the-box MES features compared to traditional systems

Best For

Mid-sized manufacturers aiming to rapidly digitize shop floor operations and empower frontline workers with tailored automation apps.

Pricing

Custom enterprise pricing; typically starts at $1,250/month per app or site, with volume discounts for larger deployments—contact sales required.

Visit Tuliptulip.co
9
Ignition by Inductive Automation logo

Ignition by Inductive Automation

specialized

Unlimited SCADA/MES platform for creating HMI, IIoT, and automation applications across manufacturing sites.

Overall Rating9.0/10
Features
9.5/10
Ease of Use
7.5/10
Value
9.5/10
Standout Feature

Unlimited tags, clients, and servers in a single license, eliminating per-point scaling costs common in traditional SCADA systems

Ignition by Inductive Automation is a modular SCADA platform tailored for manufacturing process automation, providing HMI, alarming, historian, reporting, and MES capabilities in a single architecture. It supports unlimited tags, clients, and servers under one license, enabling seamless scalability from small machines to enterprise-wide systems. With web-based deployment, it allows instant access via any browser or device without client installations, supporting a wide array of industrial protocols for real-time monitoring and control.

Pros

  • Unlimited licensing for tags, clients, and servers provides exceptional scalability without per-point costs
  • Broad protocol support including OPC UA, Modbus, and Ethernet/IP for diverse manufacturing environments
  • Web-based Perspective module delivers modern, responsive HMIs accessible on any device

Cons

  • Steep learning curve due to its powerful and flexible architecture
  • Requires Java runtime, which may introduce compatibility or security considerations
  • Higher upfront licensing cost compared to some subscription-based alternatives

Best For

Manufacturing automation engineers and system integrators needing scalable, unlimited SCADA solutions for mid-to-large industrial facilities.

Pricing

One-time perpetual licenses starting at $9,595 for Silver (up to 3 gateways), up to $22,395 for Platinum (unlimited gateways), with free Maker Edition for development.

10
AVEVA MES logo

AVEVA MES

enterprise

Manufacturing operations management software for real-time visibility, execution, and optimization of production processes.

Overall Rating8.3/10
Features
9.1/10
Ease of Use
7.4/10
Value
8.0/10
Standout Feature

Model-Driven Execution that allows flexible, configurable production models without extensive recoding

AVEVA MES is a robust Manufacturing Execution System (MES) that delivers real-time visibility, control, and optimization of manufacturing operations across discrete, batch, and continuous processes. It integrates shop floor data with enterprise systems like ERP and PLCs to track KPIs such as OEE, genealogy, and quality metrics. Designed for industrial-scale deployments, it supports digital transformation by enabling predictive analytics and model-based execution for improved efficiency and compliance.

Pros

  • Comprehensive integration with industrial protocols and AVEVA ecosystem
  • Advanced real-time analytics and OEE optimization tools
  • Scalable for global enterprises with strong compliance features

Cons

  • Complex initial setup and customization requires expert consultants
  • Steep learning curve for non-technical users
  • High licensing and implementation costs

Best For

Large-scale manufacturing enterprises in regulated industries like pharmaceuticals, food & beverage, or oil & gas seeking enterprise-grade process automation and real-time operational intelligence.

Pricing

Custom enterprise pricing; typically starts at $100,000+ annually for on-premise or cloud deployments, plus implementation fees.

Conclusion

The review of top manufacturing process automation software highlights the transformative impact of these tools on modern operations. Leading the way is Plex, a cloud-native ERP and MES platform that excels in automating end-to-end processes from shop floor to supply chain, setting a benchmark for integration and efficiency. Close behind, Epicor Kinetic and Siemens Opcenter stand out—Epicor for its robust integrated ERP and MES, and Siemens for advanced analytics and planning, offering tailored alternatives for diverse operational needs. Together, these tools showcase the power of automation in driving productivity and quality.

Plex logo
Our Top Pick
Plex

Begin your journey to streamlined manufacturing with Plex, the top-ranked solution, and unlock seamless end-to-end automation that enhances efficiency and performance.