Top 10 Best Manufacturing Documentation Software of 2026

MasterControl is a leading enterprise quality management system (QMS) software tailored for regulated manufacturing industries like pharmaceuticals, medical devices, and biotech. It provides robust document control capabilities, including version management, electronic signatures, audit trails, and automated workflows to ensure compliance with FDA 21 CFR Part 11, ISO 13485, and other standards. Beyond documentation, it integrates CAPA, training management, non-conformance reporting, and supplier management to streamline the entire manufacturing quality lifecycle.

Siemens Teamcenter is a leading Product Lifecycle Management (PLM) platform designed to manage the entire product development process, with strong capabilities in manufacturing documentation including CAD data, bills of materials (BOMs), work instructions, and engineering change orders. It provides a centralized digital thread that connects design, manufacturing, and service teams, ensuring version control, compliance, and real-time collaboration. Teamcenter supports advanced visualization tools and integrations with ERP and MES systems, making it suitable for complex, regulated industries like aerospace and automotive.

PTC Windchill is a robust Product Lifecycle Management (PLM) platform designed to manage product data from design through manufacturing and service. It excels in manufacturing documentation by providing advanced BOM management, digital work instructions, change management, and quality control tools. The software ensures traceability and collaboration across extended enterprises, integrating seamlessly with CAD systems like Creo.

Dozuki is a cloud-based digital work instruction platform tailored for manufacturing, enabling the creation of interactive, visual guides with step-by-step instructions, images, videos, and AR overlays. It streamlines documentation management, supports version control, and facilitates real-time feedback from the shop floor to drive continuous improvement and compliance. Ideal for replacing paper-based processes, it integrates with MES, ERP, and quality systems to standardize operations across global teams.

Autodesk Vault is a robust product data management (PDM) solution that enables manufacturing teams to securely store, version, and collaborate on design files, drawings, BOMs, and documentation. It integrates seamlessly with Autodesk tools like Inventor and AutoCAD to automate workflows, track changes, and ensure compliance in manufacturing processes. Vault supports lifecycle management from design to production, making it suitable for handling complex manufacturing documentation needs.

ComplianceQuest is a cloud-based Quality Management System (QMS) built on the Salesforce platform, specializing in compliance, document control, and EHSQ processes for manufacturing environments. It enables centralized management of documentation, SOPs, work instructions, audits, CAPA, and training records to ensure regulatory compliance like ISO 9001 and FDA standards. The software leverages Salesforce's scalability for customizable workflows and real-time collaboration across manufacturing teams.

ETQ Reliance is a robust Quality Management System (QMS) platform tailored for manufacturing, specializing in document control, version management, approvals, and compliance workflows. It automates quality processes like CAPA, audits, non-conformances, and supplier management while ensuring regulatory adherence to standards such as ISO 9001, FDA 21 CFR Part 11, and IATF 16949. The software offers electronic signatures, full audit trails, and seamless integration with ERP systems like SAP and Oracle.

PTC Arena is a cloud-based SaaS platform designed for manufacturing documentation and quality management, enabling centralized control of documents, processes, and compliance requirements. It supports CAPA (Corrective and Preventive Actions), audits, training management, and supplier collaboration, with strong traceability features for regulated industries like aerospace, medical devices, and automotive. The solution integrates seamlessly with PTC's broader ecosystem, including Creo and Windchill, to maintain a digital thread throughout the product lifecycle.

OpenBOM is a cloud-based Bill of Materials (BOM) management platform designed for engineers, manufacturers, and hardware teams to create, collaborate on, and track manufacturing documentation. It supports multi-level BOMs, part libraries, revisions, and seamless integrations with CAD tools like SolidWorks, Altium, and Fusion 360, enabling real-time updates and streamlined data flow from design to production. The tool excels in turning spreadsheets and CAD data into structured, shareable manufacturing docs with version control.

Aligni is a cloud-based parts lifecycle management platform tailored for hardware teams in manufacturing, focusing on centralized BOM management, component libraries, and compliance tracking. It enables users to search a vast database of over 1 billion parts, manage supplier data, and automate documentation for regulatory standards like RoHS and REACH. The software integrates with CAD tools like Altium and KiCad, as well as ERP systems, streamlining the transition from design to production.