Top 10 Best Managed Antivirus Software of 2026

CrowdStrike Falcon is a cloud-native endpoint detection and response (EDR) platform that delivers next-generation antivirus protection through AI-driven behavioral analysis and machine learning, preventing both known and zero-day threats. As a managed antivirus solution, it includes Falcon Complete, providing 24/7 expert-managed detection, response, and remediation services. This makes it a comprehensive security solution for organizations seeking enterprise-grade protection without building an in-house SOC.

SentinelOne Singularity is an AI-driven endpoint protection platform offering next-generation antivirus, EDR, and managed detection and response (MDR) through Vigilance services. It excels in behavioral threat detection, autonomous remediation, and ransomware rollback without relying on traditional signatures. Designed for enterprises, it provides unified visibility across endpoints, cloud, and identities, with expert-managed services for hands-off protection.

Microsoft Defender for Endpoint is an enterprise-grade endpoint detection and response (EDR) platform that combines antivirus, threat hunting, and automated response capabilities to protect devices across Windows, macOS, Linux, iOS, and Android. It leverages cloud-based AI and Microsoft’s vast threat intelligence for real-time malware detection, behavioral analysis, and attack surface reduction. As a managed antivirus solution, it integrates deeply with Microsoft 365 and Intune for centralized management and deployment.

Sophos Intercept X with MDR is an advanced endpoint protection platform that leverages deep learning AI for next-generation antivirus, exploit prevention, and ransomware defense. The integrated Managed Detection and Response (MDR) service delivers 24/7 monitoring, threat hunting, and expert-led incident response by Sophos analysts. It provides comprehensive protection for endpoints, servers, and cloud workloads through a unified cloud console.

Bitdefender GravityZone is a cloud-based endpoint security platform tailored for businesses, offering managed antivirus, EDR, patch management, and risk analytics in a single console. It leverages advanced machine learning and behavioral analysis for proactive threat detection and response across Windows, macOS, Linux, and virtual environments. Designed for MSPs and IT teams, it enables centralized control and scalability without on-premises hardware.

Huntress Managed EDR is a cloud-based endpoint detection and response (EDR) solution with managed detection and response (MDR) services, focusing on threat hunting and rapid incident response rather than traditional antivirus prevention. It deploys a lightweight agent to monitor endpoints for advanced persistent threats, ransomware, and malware evasion techniques, complemented by 24/7 human analysts who investigate alerts and perform remediation. Designed primarily for MSPs and SMBs, it augments existing AV tools like Windows Defender with proactive hunting and host isolation capabilities.

ESET PROTECT is a centralized management platform for ESET's endpoint security solutions, enabling IT admins and MSPs to deploy, monitor, and manage antivirus protection across desktops, servers, mobiles, and virtual environments from a single cloud or on-premises console. It offers real-time threat detection, automated policy enforcement, patch management, and detailed reporting to streamline security operations. With low system impact and high detection efficacy, it's designed for scalable protection in business environments.

Trend Micro Apex One is a robust endpoint security platform designed for businesses, providing comprehensive antivirus, anti-malware, ransomware protection, and endpoint detection and response (EDR) capabilities. It features a centralized management console for deploying policies across endpoints, monitoring threats in real-time, and automating responses. As a managed solution, it supports both on-premises and cloud deployments, integrating with Trend Micro's broader XDR ecosystem for enhanced visibility.

Malwarebytes Nebula is a cloud-based endpoint security platform tailored for managed service providers (MSPs), offering antivirus, endpoint detection and response (EDR), patch management, and vulnerability assessments. It provides centralized management through a multi-tenant console, enabling MSPs to monitor, remediate threats, and deploy updates across client endpoints efficiently. Nebula emphasizes behavior-based detection and automated remediation to minimize manual intervention.

Palo Alto Networks Cortex XDR is an extended detection and response (XDR) platform that goes beyond traditional antivirus by integrating endpoint protection, network analysis, and cloud security into a unified managed solution. It leverages AI-driven behavioral analytics and machine learning to detect and prevent both known and zero-day threats in real-time, with automated response capabilities. As a managed antivirus service, it provides centralized visibility, threat hunting, and expert-managed operations for enterprise environments.