Quick Overview
- 1#1: Kareo - Cloud-based medical billing and practice management software that streamlines claims processing and revenue cycle management for independent practices.
- 2#2: AdvancedMD - Comprehensive EHR and billing platform offering automated claims submission, denial management, and patient payments for specialty practices.
- 3#3: athenaOne - Cloud-based EHR and revenue cycle management solution with AI-driven billing optimization and interoperability for mid-sized practices.
- 4#4: DrChrono - Mobile-first EHR and medical billing software with real-time claims tracking and integrated telehealth for efficient practice workflows.
- 5#5: NextGen Healthcare - Enterprise-grade EHR and practice management system featuring advanced billing rules engine and analytics for large healthcare organizations.
- 6#6: eClinicalWorks - Integrated EHR, practice management, and billing software with patient engagement tools and robust claims scrubbing capabilities.
- 7#7: Practice Fusion - Free cloud-based EHR with integrated medical billing, e-prescribing, and scheduling for small to medium-sized practices.
- 8#8: CureMD - All-in-one EHR and billing platform with customizable workflows, denial management, and reporting for specialty clinics.
- 9#9: CollaborateMD - Web-based practice management and medical billing software focused on claims processing and eligibility verification.
- 10#10: OfficeAlly - Online portal for medical billing, claims submission, and ERA posting with affordable pricing for small practices.
We evaluated these tools based on key metrics including claims processing efficiency, user-friendliness, integration capabilities, and value for money, ensuring they deliver robust performance tailored to diverse practice requirements.
Comparison Table
Medical billing software is essential for optimizing practice workflows, and exploring options such as Kareo, AdvancedMD, athenaOne, DrChrono, NextGen Healthcare, and more can help practices find their ideal solution. This comparison table simplifies decision-making by detailing key features, pricing structures, and usability to guide readers toward the right tool.
| # | Tool | Category | Overall | Features | Ease of Use | Value |
|---|---|---|---|---|---|---|
| 1 | Kareo Cloud-based medical billing and practice management software that streamlines claims processing and revenue cycle management for independent practices. | specialized | 9.7/10 | 9.8/10 | 9.4/10 | 9.5/10 |
| 2 | AdvancedMD Comprehensive EHR and billing platform offering automated claims submission, denial management, and patient payments for specialty practices. | enterprise | 9.1/10 | 9.4/10 | 8.6/10 | 8.7/10 |
| 3 | athenaOne Cloud-based EHR and revenue cycle management solution with AI-driven billing optimization and interoperability for mid-sized practices. | enterprise | 8.4/10 | 9.1/10 | 7.8/10 | 7.9/10 |
| 4 | DrChrono Mobile-first EHR and medical billing software with real-time claims tracking and integrated telehealth for efficient practice workflows. | specialized | 8.7/10 | 9.2/10 | 8.1/10 | 8.3/10 |
| 5 | NextGen Healthcare Enterprise-grade EHR and practice management system featuring advanced billing rules engine and analytics for large healthcare organizations. | enterprise | 8.7/10 | 9.2/10 | 7.8/10 | 8.0/10 |
| 6 | eClinicalWorks Integrated EHR, practice management, and billing software with patient engagement tools and robust claims scrubbing capabilities. | enterprise | 8.2/10 | 8.9/10 | 7.1/10 | 7.8/10 |
| 7 | Practice Fusion Free cloud-based EHR with integrated medical billing, e-prescribing, and scheduling for small to medium-sized practices. | specialized | 7.6/10 | 7.4/10 | 8.2/10 | 8.9/10 |
| 8 | CureMD All-in-one EHR and billing platform with customizable workflows, denial management, and reporting for specialty clinics. | specialized | 8.1/10 | 8.5/10 | 7.6/10 | 7.9/10 |
| 9 | CollaborateMD Web-based practice management and medical billing software focused on claims processing and eligibility verification. | specialized | 8.1/10 | 8.5/10 | 7.9/10 | 7.8/10 |
| 10 | OfficeAlly Online portal for medical billing, claims submission, and ERA posting with affordable pricing for small practices. | other | 7.6/10 | 7.8/10 | 7.4/10 | 8.2/10 |
Cloud-based medical billing and practice management software that streamlines claims processing and revenue cycle management for independent practices.
Comprehensive EHR and billing platform offering automated claims submission, denial management, and patient payments for specialty practices.
Cloud-based EHR and revenue cycle management solution with AI-driven billing optimization and interoperability for mid-sized practices.
Mobile-first EHR and medical billing software with real-time claims tracking and integrated telehealth for efficient practice workflows.
Enterprise-grade EHR and practice management system featuring advanced billing rules engine and analytics for large healthcare organizations.
Integrated EHR, practice management, and billing software with patient engagement tools and robust claims scrubbing capabilities.
Free cloud-based EHR with integrated medical billing, e-prescribing, and scheduling for small to medium-sized practices.
All-in-one EHR and billing platform with customizable workflows, denial management, and reporting for specialty clinics.
Web-based practice management and medical billing software focused on claims processing and eligibility verification.
Online portal for medical billing, claims submission, and ERA posting with affordable pricing for small practices.
Kareo
specializedCloud-based medical billing and practice management software that streamlines claims processing and revenue cycle management for independent practices.
Kareo Intelligence AI analytics for predictive denial prevention and revenue optimization
Kareo is a cloud-based medical billing and revenue cycle management platform designed specifically for independent medical practices, offering end-to-end automation for claims processing, patient payments, and denial management. It integrates seamlessly with EHR and practice management tools to streamline workflows and maximize reimbursements. With advanced analytics and AI-powered insights, Kareo helps providers achieve higher clean claim rates, often exceeding 98%, while supporting specialties like behavioral health and therapy.
Pros
- Comprehensive revenue cycle management with automated claims scrubbing and 99% first-pass acceptance rates
- Integrated EHR, scheduling, and patient portal for all-in-one practice efficiency
- Robust analytics dashboard and dedicated support for quick onboarding and issue resolution
Cons
- Pricing can be steep for very small solo practices without scaling discounts
- Advanced custom integrations may require additional setup time
- Occasional reports of minor UI glitches during peak usage periods
Best For
Small to mid-sized independent medical practices and specialties like behavioral health needing a scalable, all-in-one billing and practice management solution.
Pricing
Starts at $110/provider/month for core billing, with full practice management bundles from $300-$500+/month based on practice size; custom enterprise quotes available.
AdvancedMD
enterpriseComprehensive EHR and billing platform offering automated claims submission, denial management, and patient payments for specialty practices.
AI-powered denial management that predicts and prevents claim rejections proactively
AdvancedMD is a comprehensive cloud-based platform specializing in medical billing and revenue cycle management for healthcare practices of all sizes. It streamlines claims processing, electronic remittance advice (ERA), denial management, and patient payments with robust automation and analytics. Integrated with EHR and practice management tools, it helps providers maximize reimbursements and reduce administrative burdens.
Pros
- Advanced automation for claims scrubbing and denial prevention
- Seamless integration with EHR and scheduling systems
- Real-time analytics and reporting for revenue insights
Cons
- Higher pricing tiers for full functionality
- Steep learning curve for advanced features
- Occasional customer support delays during peak times
Best For
Mid-sized to large medical practices seeking an all-in-one solution for efficient billing and revenue cycle management.
Pricing
Custom subscription starting at $400-$700 per provider/month, with additional fees for modules and setup.
athenaOne
enterpriseCloud-based EHR and revenue cycle management solution with AI-driven billing optimization and interoperability for mid-sized practices.
AI-powered Revenue Intelligence with predictive analytics for claims optimization and guaranteed performance metrics
athenaOne by athenahealth is a comprehensive cloud-based platform that combines EHR, practice management, and advanced medical billing features into one integrated solution. It excels in revenue cycle management (RCM) with automated claims processing, denial management, eligibility verification, and patient payment collection tools. The software leverages a vast payer network and AI-driven analytics to optimize billing efficiency and financial performance for healthcare providers.
Pros
- Robust RCM with high clean claims rates (often >98%) and built-in denial prevention
- Seamless integration with EHR for end-to-end workflow automation
- Cloud-based accessibility with strong security and scalability for growing practices
Cons
- High cost structure that may strain small practices' budgets
- Steep learning curve for advanced features and customization limitations
- Occasional customer support delays reported by users
Best For
Mid-sized to large medical practices seeking an all-in-one EHR and billing solution with enterprise-level RCM capabilities.
Pricing
Custom subscription pricing per provider, typically $169-$450/month plus implementation fees; quotes based on practice size and modules.
DrChrono
specializedMobile-first EHR and medical billing software with real-time claims tracking and integrated telehealth for efficient practice workflows.
Native iPad and iPhone apps that allow full charting, scheduling, and billing directly from mobile devices without desktop dependency
DrChrono is a cloud-based electronic health record (EHR) and practice management platform with integrated medical billing software designed to streamline revenue cycle management for healthcare providers. It offers automated claims submission, eligibility verification, denial management, and payment posting, all within a customizable interface that supports multiple specialties. The platform emphasizes mobility with native iOS and Android apps, enabling billing tasks on the go while integrating with major clearinghouses for efficient payer reimbursements.
Pros
- Comprehensive integration of EHR, scheduling, and billing in one platform
- High first-pass claim acceptance rates with built-in scrubbing and automation
- Native mobile apps for iOS and Android supporting full billing workflows
Cons
- Pricing can be steep for small practices with per-provider costs
- Steep learning curve for advanced customization and reporting
- Customer support response times can vary, especially during peak periods
Best For
Mid-sized medical practices and specialties needing an all-in-one EHR with robust, mobile-friendly billing capabilities.
Pricing
Custom quotes starting at around $200 per provider per month for base plans, with tiers up to $500+ including advanced features; additional fees for implementation and add-ons.
NextGen Healthcare
enterpriseEnterprise-grade EHR and practice management system featuring advanced billing rules engine and analytics for large healthcare organizations.
Predictive denial management powered by AI to proactively identify and prevent claim rejections
NextGen Healthcare offers a comprehensive EHR and practice management platform with robust medical billing capabilities, including automated claims processing, denial management, and revenue cycle management (RCM). It integrates seamlessly with clinical workflows to streamline billing for ambulatory practices, specialty groups, and health systems. The software supports electronic remittance advice (ERA), patient payments, and analytics for optimizing reimbursements.
Pros
- Advanced RCM tools with denial prediction and automated workflows
- Seamless integration with EHR for end-to-end practice management
- Scalable for mid-sized to enterprise-level practices with strong compliance features
Cons
- Steep learning curve and complex interface for new users
- High implementation costs and lengthy onboarding process
- Pricing is opaque and premium, less ideal for small practices
Best For
Mid-sized to large medical practices and health systems needing integrated EHR billing with enterprise scalability.
Pricing
Custom enterprise pricing via quote; typically $400–$800 per provider/month plus implementation fees.
eClinicalWorks
enterpriseIntegrated EHR, practice management, and billing software with patient engagement tools and robust claims scrubbing capabilities.
Prism analytics for revenue cycle insights, identifying billing bottlenecks and optimization opportunities in real-time
eClinicalWorks is a cloud-based EHR and practice management platform with robust medical billing capabilities, designed for healthcare providers. It automates revenue cycle management, including claims submission, eligibility verification, denial management, and payment posting. The software integrates billing seamlessly with patient records and supports multiple specialties, scaling from small practices to large enterprises.
Pros
- Comprehensive revenue cycle management with high claims acceptance rates
- Deep integration with EHR for accurate coding and billing
- Scalable for multi-location and multi-provider practices
Cons
- Steep learning curve and complex interface
- Customer support often criticized for slow response times
- High cost for smaller practices with additional implementation fees
Best For
Medium to large medical practices needing an integrated EHR and billing solution.
Pricing
Quote-based subscription starting at around $449 per provider per month, plus one-time setup and training fees.
Practice Fusion
specializedFree cloud-based EHR with integrated medical billing, e-prescribing, and scheduling for small to medium-sized practices.
Completely free cloud-based EHR with built-in claims submission, making it accessible for budget-conscious practices
Practice Fusion is a cloud-based electronic health record (EHR) platform that integrates medical billing capabilities, enabling practices to manage patient charts, generate superbills, submit claims electronically, and process payments. It supports eligibility verification, ERA posting, and integration with major clearinghouses for streamlined revenue cycle management. Primarily designed for small to mid-sized practices, it combines EHR functionality with billing tools in a user-friendly web interface.
Pros
- Free core EHR and basic billing features reduce upfront costs
- Intuitive web-based interface with mobile access
- Seamless integration with e-prescribing, labs, and clearinghouses
Cons
- Limited advanced billing analytics and customization compared to dedicated solutions
- Transaction fees for claims processing can add up
- Occasional performance issues due to cloud dependency
Best For
Small independent practices seeking an affordable, all-in-one EHR with integrated billing without complex setup.
Pricing
Free EHR software; billing includes per-claim fees (around $0.09-$0.19 per claim) and optional premium support subscriptions starting at $149/month.
CureMD
specializedAll-in-one EHR and billing platform with customizable workflows, denial management, and reporting for specialty clinics.
AI-powered revenue cycle management with automated coding suggestions and predictive denial prevention
CureMD is a cloud-based electronic health records (EHR) and practice management platform with integrated medical billing software designed for healthcare providers. It handles claims submission, insurance eligibility verification, electronic remittance advice (ERA) posting, denial management, and revenue cycle management (RCM) to streamline billing processes. The system supports multiple specialties with customizable templates, HIPAA compliance, and interoperability via HL7 and FHIR standards.
Pros
- Integrated EHR, practice management, and billing in one platform
- Advanced denial management and claims scrubbing tools
- Robust reporting and analytics for revenue optimization
Cons
- Steep learning curve due to complex interface
- Custom pricing can become expensive for larger practices
- Limited mobile app functionality for billing tasks
Best For
Mid-sized medical practices needing an all-in-one EHR and billing solution with strong RCM capabilities.
Pricing
Custom quotes starting at $295-$495 per provider per month, plus setup fees and add-ons for advanced modules.
CollaborateMD
specializedWeb-based practice management and medical billing software focused on claims processing and eligibility verification.
Advanced claims scrubbing engine with 99% clean claims rate on first submission
CollaborateMD is a cloud-based medical billing and practice management software tailored for healthcare providers, focusing on revenue cycle management. It automates claims submission, scrubbing, eligibility verification, denial management, and patient payments while integrating with EHR systems and clearinghouses. The platform provides robust reporting tools and supports specialties like behavioral health and therapy.
Pros
- High first-pass claims acceptance rate (up to 99%)
- Strong clearinghouse integrations and denial management
- Responsive customer support with dedicated billing experts
Cons
- Pricing scales quickly with multiple providers
- Limited advanced customization options
- Steeper learning curve for non-tech-savvy users
Best For
Small to mid-sized medical practices seeking reliable, automated billing without in-house expertise.
Pricing
Starts at $399/month for basic plans; per-provider pricing from $300-$500/month plus setup fees and transaction costs.
OfficeAlly
otherOnline portal for medical billing, claims submission, and ERA posting with affordable pricing for small practices.
Free claims scrubbing and eligibility verification for members, reducing denials before submission
OfficeAlly is a web-based medical billing and clearinghouse platform that facilitates electronic claims submission, eligibility verification, and remittance processing for healthcare providers. It offers integrated practice management tools, patient payment portals, and revenue cycle management services to streamline billing workflows. Primarily designed for small to mid-sized practices, it connects to thousands of payers and supports both professional and institutional claims.
Pros
- Cost-effective pay-per-claim model with low transaction fees
- High claims acceptance rates and reliable payer connectivity
- Integrated patient portal for statements and payments
Cons
- Dated user interface in some modules
- Limited advanced EHR customization options
- Customer support can be slow during peak times
Best For
Small to medium-sized medical practices needing affordable, reliable claims processing without full-featured EHR requirements.
Pricing
Pay-per-use clearinghouse fees ($0.09-$0.25 per claim); practice management subscriptions from $149/month; free basic tools for high-volume users.
Conclusion
The top tools reviewed vary in focus, but Kareo emerges as the clear leader, streamlining claims processing and revenue cycle management for independent practices. AdvancedMD follows, a strong pick for specialty practices with automated claims and denial management, while athenaOne excels in mid-sized settings with AI-driven optimization and interoperability. Each offers unique strengths, ensuring providers can find the right fit, though Kareo sets the standard for overall efficiency.
To boost your practice's revenue workflow, start with Kareo—its streamlined tools are designed to simplify billing. For other needs, explore AdvancedMD or athenaOne, as they cater to specialized practices and larger teams, ensuring you find the ideal solution.
Tools Reviewed
All tools were independently evaluated for this comparison
