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Top 10 Best Laboratory Sample Tracking Software of 2026

Discover the best lab sample tracking software to streamline workflows. Compare top tools, features, and choose the perfect fit today.

Min-ji Park

Min-ji Park

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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In modern labs, precise sample tracking is essential for maintaining data integrity, meeting regulatory standards, and boosting operational efficiency—making the right software a key investment. With a spectrum of tools designed to suit industries from biotech to pharma and high-throughput research, selecting the ideal solution demands balancing functionality, usability, and fit for specific workflows. This curated list highlights the leading options shaping lab operations today.

Quick Overview

  1. 1#1: LabWare LIMS - Delivers enterprise-grade sample tracking, workflow automation, and compliance management for laboratories across industries.
  2. 2#2: STARLIMS - Offers configurable LIMS for precise sample tracking, inventory control, and regulatory compliance in diverse lab environments.
  3. 3#3: LabVantage - Provides next-generation LIMS with advanced sample management, real-time analytics, and seamless integration capabilities.
  4. 4#4: Thermo Scientific SampleManager - Enables robust sample lifecycle tracking, data integrity, and instrument integration for biopharma and analytical labs.
  5. 5#5: Benchling - Cloud-native platform for biotech R&D with intuitive sample tracking, inventory, and collaboration tools.
  6. 6#6: Titian Mosaic - Specialized sample management system for tracking compound libraries, aliquots, and storage in high-throughput labs.
  7. 7#7: CloudLIMS - Cloud-based LIMS for streamlined sample tracking, quality control, and reporting in regulated laboratories.
  8. 8#8: QBench - Next-gen LIMS offering real-time sample tracking, workflow automation, and customizable dashboards for modern labs.
  9. 9#9: Labguru - All-in-one ELN and LIMS platform for sample management, experiment tracking, and team collaboration.
  10. 10#10: eLabNext - Digital lab platform providing sample inventory tracking, request management, and integration with lab instruments.

Tools were chosen based on rigorous evaluation of core capabilities (sample lifecycle management, integration, compliance), reliability, user-friendliness, and demonstrated value across diverse lab environments, ensuring they address both critical needs and long-term scalability.

Comparison Table

Accurate and efficient sample tracking is vital for lab operations, with the right software streamlining workflows and ensuring compliance. This comparison table examines top tools like LabWare LIMS, STARLIMS, LabVantage, Thermo Scientific SampleManager, Benchling, and more, to help identify the best fit for diverse needs. Readers will gain insights into key features, scalability, and usability to make informed decisions.

Delivers enterprise-grade sample tracking, workflow automation, and compliance management for laboratories across industries.

Features
9.8/10
Ease
8.2/10
Value
9.1/10
2STARLIMS logo9.2/10

Offers configurable LIMS for precise sample tracking, inventory control, and regulatory compliance in diverse lab environments.

Features
9.6/10
Ease
7.8/10
Value
8.4/10
3LabVantage logo8.7/10

Provides next-generation LIMS with advanced sample management, real-time analytics, and seamless integration capabilities.

Features
9.4/10
Ease
7.8/10
Value
8.2/10

Enables robust sample lifecycle tracking, data integrity, and instrument integration for biopharma and analytical labs.

Features
9.2/10
Ease
7.5/10
Value
8.0/10
5Benchling logo8.7/10

Cloud-native platform for biotech R&D with intuitive sample tracking, inventory, and collaboration tools.

Features
9.2/10
Ease
8.5/10
Value
7.8/10

Specialized sample management system for tracking compound libraries, aliquots, and storage in high-throughput labs.

Features
9.1/10
Ease
7.4/10
Value
7.7/10
7CloudLIMS logo8.6/10

Cloud-based LIMS for streamlined sample tracking, quality control, and reporting in regulated laboratories.

Features
9.1/10
Ease
7.7/10
Value
8.2/10
8QBench logo8.1/10

Next-gen LIMS offering real-time sample tracking, workflow automation, and customizable dashboards for modern labs.

Features
8.5/10
Ease
7.7/10
Value
7.6/10
9Labguru logo8.3/10

All-in-one ELN and LIMS platform for sample management, experiment tracking, and team collaboration.

Features
8.7/10
Ease
8.2/10
Value
7.9/10
10eLabNext logo8.1/10

Digital lab platform providing sample inventory tracking, request management, and integration with lab instruments.

Features
8.4/10
Ease
8.9/10
Value
7.6/10
1
LabWare LIMS logo

LabWare LIMS

enterprise

Delivers enterprise-grade sample tracking, workflow automation, and compliance management for laboratories across industries.

Overall Rating9.5/10
Features
9.8/10
Ease of Use
8.2/10
Value
9.1/10
Standout Feature

Point-and-click configurability enabling labs to customize workflows, forms, and reports without programming expertise

LabWare LIMS is a comprehensive Laboratory Information Management System designed to streamline sample tracking, workflow automation, and data management across diverse laboratory environments. It excels in tracking samples from receipt through testing and reporting, ensuring chain-of-custody compliance and regulatory adherence like 21 CFR Part 11 and ISO 17025. With robust instrument integration and customizable modules, it supports industries such as pharmaceuticals, biotech, environmental testing, and food safety.

Pros

  • Exceptional configurability without custom coding, allowing rapid adaptation to lab-specific workflows
  • Superior sample tracking with full chain-of-custody, barcode/RFID support, and real-time status updates
  • Seamless integration with hundreds of lab instruments and third-party systems for automated data capture

Cons

  • Steep learning curve and complex initial setup requiring expert implementation
  • High upfront costs and ongoing maintenance fees
  • Limited out-of-the-box simplicity for small labs without dedicated IT support

Best For

Enterprise-level laboratories in highly regulated industries like pharmaceuticals, biotechnology, and clinical research needing scalable, compliant sample management.

Pricing

Quote-based enterprise licensing starting at $50,000+ annually, depending on modules, users, and deployment scale; perpetual licenses with annual support also available.

2
STARLIMS logo

STARLIMS

enterprise

Offers configurable LIMS for precise sample tracking, inventory control, and regulatory compliance in diverse lab environments.

Overall Rating9.2/10
Features
9.6/10
Ease of Use
7.8/10
Value
8.4/10
Standout Feature

Advanced workflow engine with AI-driven automation for dynamic, rule-based sample routing and exception handling

STARLIMS is a robust Laboratory Information Management System (LIMS) from Abbott Informatics, specializing in end-to-end laboratory sample tracking and management across diverse industries like pharmaceuticals, biotech, clinical, and environmental testing. It automates sample accessioning, processing, storage, and disposal with full chain-of-custody traceability, barcode/RFID support, and real-time status updates. The platform ensures regulatory compliance (e.g., FDA 21 CFR Part 11, ISO 17025) through audit trails, electronic signatures, and configurable workflows.

Pros

  • Exceptional sample lifecycle tracking with real-time visibility and automation
  • Deep regulatory compliance tools and audit-proof documentation
  • Highly customizable workflows and seamless instrument/ERP integrations
  • Scalable for high-volume labs with advanced analytics and reporting

Cons

  • Steep learning curve and complex initial setup requiring IT expertise
  • Enterprise-level pricing not suitable for small labs
  • Customization can extend implementation timelines

Best For

Large, regulated laboratories in pharma, clinical, or biotech needing enterprise-grade sample tracking and compliance.

Pricing

Custom enterprise pricing via quote; typically $50,000+ annually for mid-sized deployments, based on users, modules, and hosting (on-premise or cloud).

Visit STARLIMSstarlims.com
3
LabVantage logo

LabVantage

enterprise

Provides next-generation LIMS with advanced sample management, real-time analytics, and seamless integration capabilities.

Overall Rating8.7/10
Features
9.4/10
Ease of Use
7.8/10
Value
8.2/10
Standout Feature

Visual Workflow Designer enabling no-code customization of intricate sample management processes

LabVantage is a robust Laboratory Information Management System (LIMS) that provides comprehensive sample tracking, management, and workflow automation for laboratories in pharmaceuticals, biotech, clinical, and research sectors. It offers end-to-end visibility into sample lifecycle, including accessioning, processing, storage, and disposal, with support for barcodes, RFID, and mobile tracking. The platform ensures data integrity and regulatory compliance through features like full audit trails and electronic signatures.

Pros

  • Advanced sample lineage tracking with real-time status updates and full audit trails
  • Highly configurable no-code workflows for complex lab processes
  • Seamless integration with lab instruments and ELN/SDMS systems

Cons

  • Steep learning curve and extensive training required
  • High implementation costs and long deployment times
  • Overkill for small labs due to enterprise focus

Best For

Enterprise-level laboratories in regulated industries like pharma and biotech needing scalable, compliant sample tracking.

Pricing

Custom enterprise pricing; typically $100,000+ annually based on modules, users, and deployment scale.

Visit LabVantagelabvantage.com
4
Thermo Scientific SampleManager logo

Thermo Scientific SampleManager

enterprise

Enables robust sample lifecycle tracking, data integrity, and instrument integration for biopharma and analytical labs.

Overall Rating8.4/10
Features
9.2/10
Ease of Use
7.5/10
Value
8.0/10
Standout Feature

Unified platform combining LIMS, ELN, and SDMS for seamless end-to-end lab data management

Thermo Scientific SampleManager is a comprehensive Laboratory Information Management System (LIMS) designed for tracking and managing samples throughout their lifecycle in regulated environments. It offers real-time sample tracking via barcodes and RFID, workflow automation, instrument integration, and ensures compliance with standards like 21 CFR Part 11 and ISO 17025. The platform also includes built-in ELN and SDMS capabilities for a unified lab data management experience.

Pros

  • Robust sample tracking with real-time visibility and audit trails
  • Extensive instrument integrations, especially Thermo Fisher ecosystem
  • Strong regulatory compliance and configurable workflows

Cons

  • Steep learning curve for non-expert users
  • Complex and lengthy implementation process
  • High cost for smaller labs

Best For

Enterprise-level labs in pharmaceuticals, biotech, and food safety requiring scalable, compliant sample tracking.

Pricing

Custom enterprise pricing; typically annual subscriptions starting at $100,000+ depending on modules and scale.

5
Benchling logo

Benchling

specialized

Cloud-native platform for biotech R&D with intuitive sample tracking, inventory, and collaboration tools.

Overall Rating8.7/10
Features
9.2/10
Ease of Use
8.5/10
Value
7.8/10
Standout Feature

Intelligent sample lineage visualization that automatically traces samples across experiments, reagents, and storage for complete audit trails.

Benchling is a cloud-based platform tailored for life sciences R&D, providing advanced laboratory sample tracking through its inventory management system that supports barcoding, custom schemas, and full lineage tracing. It enables teams to manage samples from registration to disposal, with real-time visibility into storage locations, usage, and associated experiments. Integrated with ELN, molecular design tools, and collaboration features, it streamlines workflows for biotech and pharma labs.

Pros

  • Comprehensive sample lineage tracking with automated linkages to experiments and reagents
  • Scalable cloud infrastructure supporting barcode scanning and real-time inventory updates
  • Seamless integration with ELN, protocols, and external LIMS systems

Cons

  • High enterprise-level pricing limits accessibility for small labs
  • Steep learning curve for custom schema setup and advanced features
  • Primarily optimized for biotech workflows, less ideal for general chemistry or clinical labs

Best For

Mid-to-large biotech and pharmaceutical R&D teams needing integrated, scalable sample tracking with collaboration tools.

Pricing

Custom enterprise pricing starting at around $100/user/month; free tier available for academic and non-commercial use.

Visit Benchlingbenchling.com
6
Titian Mosaic logo

Titian Mosaic

specialized

Specialized sample management system for tracking compound libraries, aliquots, and storage in high-throughput labs.

Overall Rating8.2/10
Features
9.1/10
Ease of Use
7.4/10
Value
7.7/10
Standout Feature

Sample Passport technology, which creates a portable digital record of each sample's complete history, location, and metadata across systems.

Titian Mosaic is an enterprise-grade sample management software tailored for life sciences laboratories, biobanks, and pharma R&D, providing end-to-end tracking of samples from intake through storage, processing, and disposal. It features automated workflows, real-time inventory visibility, barcode/RFID support, and seamless integration with lab instruments like liquid handlers. The platform emphasizes compliance with audit trails, electronic signatures, and regulatory standards such as 21 CFR Part 11.

Pros

  • Comprehensive sample lifecycle tracking with full audit compliance
  • Strong integrations with lab automation and LIMS systems
  • Scalable for high-volume operations in biobanks and pharma

Cons

  • Steep learning curve and complex initial setup
  • High cost unsuitable for small labs
  • Primarily geared toward on-premise or hybrid deployments with limited mobile access

Best For

Large pharmaceutical companies, biobanks, and research institutions handling high volumes of diverse samples requiring strict regulatory compliance.

Pricing

Custom enterprise pricing via quote; typically starts at $50,000+ annually for mid-scale deployments, scaling with users and modules.

7
CloudLIMS logo

CloudLIMS

specialized

Cloud-based LIMS for streamlined sample tracking, quality control, and reporting in regulated laboratories.

Overall Rating8.6/10
Features
9.1/10
Ease of Use
7.7/10
Value
8.2/10
Standout Feature

COFR+ (CloudLIMS Online Forensic Request) for secure chain-of-custody tracking with unbreakable audit trails

CloudLIMS is a cloud-based Laboratory Information Management System (LIMS) designed specifically for tracking and managing laboratory samples throughout their lifecycle. It offers features like sample accessioning, barcode/RFID tracking, inventory management, workflow automation, and integration with lab instruments. The platform ensures compliance with standards such as FDA 21 CFR Part 11, ISO 17025, and GLP, making it suitable for regulated environments like clinical, biotech, and food testing labs.

Pros

  • Comprehensive sample tracking with barcode, RFID, and real-time location monitoring
  • Strong compliance tools including audit trails, electronic signatures, and validation protocols
  • Customizable workflows and seamless integration with instruments and ERP systems

Cons

  • Steep learning curve for complex configurations and customizations
  • Pricing is quote-based and can be expensive for small labs
  • Customer support response times can vary, especially for non-enterprise users

Best For

Mid-to-large laboratories in regulated industries like biotech, clinical testing, and pharma that require robust sample tracking and compliance management.

Pricing

Custom quote-based pricing starting around $500/month for basic plans, scaling with users, modules, and lab size; free demo available.

Visit CloudLIMScloudlims.com
8
QBench logo

QBench

specialized

Next-gen LIMS offering real-time sample tracking, workflow automation, and customizable dashboards for modern labs.

Overall Rating8.1/10
Features
8.5/10
Ease of Use
7.7/10
Value
7.6/10
Standout Feature

No-code Workflow Builder for creating dynamic, automated lab processes without programming

QBench is a cloud-based Laboratory Information Management System (LIMS) that provides comprehensive sample tracking from intake to disposal, enabling labs to manage workflows, inventory, and data in real-time. It supports automation through customizable no-code workflows, instrument integrations, and compliance tools for GLP and ISO standards. Designed for biotech, clinical, and research labs, it offers dashboards for visibility and reporting to enhance efficiency and reduce errors.

Pros

  • Robust end-to-end sample tracking with real-time status updates
  • Flexible no-code workflow automation and instrument integrations
  • Scalable cloud platform with mobile access and strong reporting tools

Cons

  • Steep learning curve for complex customizations
  • Pricing can be expensive for small labs or startups
  • Some users report slower performance with very large datasets

Best For

Mid-sized biotech, clinical, or research labs needing scalable sample tracking and workflow automation.

Pricing

Custom quote-based pricing, typically starting at $500-$1,000/month for small teams, scaling with users, samples, and features.

Visit QBenchqbench.net
9
Labguru logo

Labguru

specialized

All-in-one ELN and LIMS platform for sample management, experiment tracking, and team collaboration.

Overall Rating8.3/10
Features
8.7/10
Ease of Use
8.2/10
Value
7.9/10
Standout Feature

Unified ELN-LIMS platform with visual workflow builder for end-to-end sample tracking and experiment reproducibility

Labguru is a cloud-based ELN and LIMS platform designed for life sciences labs, offering comprehensive sample tracking from registration and storage to analysis and disposal. It features barcode/RFID scanning, sample genealogy, inventory management, and automated workflows to ensure traceability and compliance with standards like GLP and 21 CFR Part 11. The software integrates experiment documentation with sample management, enabling real-time collaboration and data visualization across teams.

Pros

  • Robust sample lifecycle tracking with genealogy and chain-of-custody features
  • Seamless integration of ELN, LIMS, and inventory in one platform
  • Strong compliance tools and instrument integrations for efficient workflows

Cons

  • Pricing is quote-based and can be expensive for small labs
  • Initial setup and customization require significant configuration
  • Mobile app lacks some advanced desktop features

Best For

Mid-sized biotech, pharma, and academic research labs needing an integrated ELN-LIMS solution for sample tracking and experiment management.

Pricing

Custom quote-based pricing, typically starting at $100-200 per user per month depending on features and scale; free trial available.

Visit Labgurulabguru.com
10
eLabNext logo

eLabNext

specialized

Digital lab platform providing sample inventory tracking, request management, and integration with lab instruments.

Overall Rating8.1/10
Features
8.4/10
Ease of Use
8.9/10
Value
7.6/10
Standout Feature

Visual sample lineage mapping that provides a complete, interactive history of sample processing and transformations

eLabNext is a cloud-based Laboratory Information Management System (LIMS) designed for sample tracking, inventory management, and experiment documentation in research labs. It enables users to track samples through their entire lifecycle with barcode/RFID support, customizable workflows, and full lineage visibility. The platform integrates an electronic lab notebook (ELN) for seamless data capture and collaboration across teams.

Pros

  • Intuitive, no-code interface for quick setup and customization
  • Robust sample tracking with visual lineage and automated workflows
  • Strong collaboration tools including shared ELN and real-time notifications

Cons

  • Limited built-in advanced analytics compared to enterprise LIMS
  • Pricing scales quickly for larger teams or advanced features
  • Some integrations require custom development

Best For

Small to mid-sized biotech and academic labs needing an user-friendly solution for sample tracking and experiment management.

Pricing

Free tier for academics; commercial plans start at ~$99/user/month for Pro, with Enterprise custom pricing.

Visit eLabNextelabnext.com

Conclusion

The reviewed tools, varying from enterprise solutions to specialized platforms, showcase diverse strengths in sample tracking, automation, and compliance. At the top, LabWare LIMS leads with its comprehensive enterprise-grade management, while STARLIMS and LabVantage stand as strong alternatives, excelling in tailored compliance and real-time analytics respectively. Whether for broad industry use or niche workflows, these tools reflect modern lab innovation.

LabWare LIMS logo
Our Top Pick
LabWare LIMS

Explore LabWare LIMS first to leverage its full suite of features, but don't overlook STARLIMS or LabVantage if specific operational or industry needs demand a focused solution.