Top 10 Best Insurance Billing Software of 2026

Kareo is a cloud-based revenue cycle management platform tailored for independent medical practices and billing companies, excelling in insurance billing with automated claims submission, scrubbing, and tracking. It integrates EHR, practice management, and patient payment tools to streamline the entire billing process from charge entry to reimbursement. Kareo's analytics and denial management features help maximize collections and reduce revenue leakage, making it a top choice for efficient insurance billing.

AdvancedMD is a cloud-based practice management and EHR platform with robust insurance billing features tailored for medical practices. It automates the revenue cycle management (RCM) process, including electronic claims submission to over 2,500 payers, real-time eligibility verification, automated scrubbing, and denial management. The software integrates billing seamlessly with scheduling, patient records, and reporting for efficient practice operations.

Waystar is a comprehensive revenue cycle management (RCM) platform tailored for healthcare providers, focusing on insurance billing, claims processing, and payment optimization. It automates claims scrubbing, submission, denial management, and payment posting to reduce errors and accelerate reimbursements. The software integrates with EHR systems and offers analytics for financial insights, serving hospitals, physician groups, and health systems.

athenahealth is a cloud-based platform offering integrated EHR, practice management, and revenue cycle management (RCM) tools, with strong capabilities in insurance billing. It automates claims submission, scrubbing, eligibility verification, and denial management to optimize reimbursements and reduce errors. Designed for healthcare providers, it ensures HIPAA compliance and provides real-time analytics for financial performance.

DrChrono is a cloud-based EHR and practice management platform with robust insurance billing tools designed for medical practices. It supports electronic claims submission to over 3,000 payers, real-time eligibility verification, automated ERA payment posting, and denial management workflows. The software integrates billing seamlessly with patient charting, scheduling, and telehealth for efficient revenue cycle management.

NextGen Healthcare provides a robust revenue cycle management (RCM) solution integrated within its Enterprise EHR platform, specializing in insurance billing for ambulatory care providers. It automates claims submission, scrubbing, eligibility checks, denial management, and payment reconciliation to optimize reimbursements. The software supports multi-specialty practices with advanced analytics for revenue leakage prevention and compliance with HIPAA and payer requirements.

eClinicalWorks is a comprehensive EHR and practice management platform with integrated insurance billing capabilities, supporting electronic claims submission to over 2,500 payers, eligibility verification, and denial management. It automates revenue cycle processes like charge capture, payment posting, and AR tracking, seamlessly linking billing to patient records and scheduling. The system includes reporting tools for financial analytics and compliance with standards like HIPAA and MIPS.

CollaborateMD is a cloud-based medical billing software tailored for healthcare practices, focusing on streamlining insurance claims processing, patient payments, and revenue cycle management. It supports electronic submission to over 3,000 payers, eligibility verification, denial management, and automated remittance posting. The platform integrates seamlessly with popular EHRs and practice management systems, providing robust reporting for financial insights.

CureMD is a cloud-based Electronic Health Records (EHR) and practice management platform with robust insurance billing features tailored for medical practices. It supports electronic claims submission to over 4,000 payers, automated eligibility verification, denial management, and revenue cycle analytics to streamline billing workflows. The software integrates seamlessly with EHR functionalities, enabling efficient patient data flow from documentation to payment posting.

Practice Fusion is a cloud-based electronic health record (EHR) platform that includes integrated insurance billing tools, enabling users to generate superbills, electronic claims (HCFA 1500 and UB04), and manage reimbursements directly from patient charts. It supports ICD-10, CPT, and HCPCS coding with eligibility verification and integrates with major clearinghouses for claims submission. While primarily an EHR solution, its billing module caters to small practices handling basic to moderate insurance workflows.