Top 10 Best Instrument Calibration Software of 2026

Fluke MET/CAL is the industry-leading instrument calibration software that automates calibration procedures for electrical, RF, temperature, pressure, dimensional, and flow instruments. It features the world's largest library of over 8,000 pre-built, validated procedures and seamlessly integrates with Fluke calibration hardware for precise control and data capture. The software manages asset inventories, schedules calibrations, generates ISO 17025-compliant certificates, and supports full workflow automation in metrology labs.

GAGEtrak is a comprehensive calibration management software tailored for tracking and maintaining calibration records of gages and test equipment in industries like manufacturing and aerospace. It automates scheduling, generates certificates of calibration, and provides detailed history and reporting to ensure compliance with standards such as ISO 17025 and ISO 9001. The software supports asset lifecycle management, from acquisition to disposal, with tools for pass/fail decisions, cost tracking, and audit preparation.

ProCalV5 from Prime Technologies is a robust calibration management software tailored for instrument calibration in regulated industries like pharmaceuticals, manufacturing, and biotech. It automates workflows for scheduling, executing, and documenting calibrations, while providing tools for asset tracking, procedure libraries, and compliance reporting. The platform ensures adherence to standards such as 21 CFR Part 11, ISO 17025, and FDA requirements through electronic signatures and audit trails.

Beamex Business Suite (BBS) is an enterprise-grade calibration management software from Beamex, designed for planning, executing, documenting, and analyzing instrument calibrations in regulated industries. It provides full asset lifecycle management, automated workflows, uncertainty calculations, and seamless integration with CMMS systems like SAP and Maximo. BBS ensures compliance with standards such as ISO 17025, FDA 21 CFR Part 11, and supports mobile calibration via tablets and Beamex hardware.

Qualer is a cloud-based calibration management software tailored for regulated industries like pharmaceuticals, biotech, manufacturing, and labs. It centralizes instrument calibration tracking, scheduling, workflows, and compliance reporting to meet standards such as ISO 17025, FDA 21 CFR Part 11, and GxP. The platform also integrates asset management, preventive maintenance, vendor management, and mobile accessibility for on-the-go calibrations and audits.

CompuCal by Hexagon is a web-based calibration management software tailored for instrument calibration in manufacturing and quality assurance environments. It automates the full calibration lifecycle, including scheduling, execution, traceability, and reporting, while ensuring compliance with standards like ISO 17025 and FDA regulations. The platform supports diverse instruments, asset management, and integration with ERP/CMMS systems for streamlined operations.

EtQ Reliance is a comprehensive Enterprise Quality Management System (eQMS) platform that includes a dedicated instrument calibration module for managing calibration schedules, workflows, and compliance. It automates tracking of calibration due dates, historical records, and vendor management while integrating with broader asset management and corrective action processes. Ideal for regulated industries like manufacturing, pharma, and aerospace, it ensures traceability and adherence to standards such as ISO 17025 and FDA 21 CFR Part 11.

MasterControl is an enterprise-grade quality management system (QMS) that includes specialized instrument calibration management as part of its asset and maintenance modules. It automates calibration scheduling, procedure execution, data collection, and reporting while ensuring compliance with standards like ISO 17025, 21 CFR Part 11, and FDA regulations. The software provides full traceability through audit trails, electronic signatures, and integration with other QMS processes such as CAPA and document control.

ComplianceQuest is a cloud-based Enterprise Quality Management System (eQMS) built on Salesforce, offering specialized instrument calibration management as part of its broader compliance and asset management suite. It enables tracking of calibration schedules, histories, certificates, and vendor management while ensuring traceability and regulatory compliance (e.g., ISO 17025, FDA). The platform automates workflows, generates reports, and integrates with maintenance systems for seamless operations in regulated environments.

ValGenesis is a cloud-based digital validation platform designed for life sciences industries, featuring an integrated instrument calibration management module that automates scheduling, execution, and documentation. It ensures full compliance with FDA 21 CFR Part 11 and other GMP regulations through electronic signatures, audit trails, and real-time data capture. The software links calibration activities to broader validation lifecycle management, reducing paper-based processes and minimizing errors in regulated environments.