Quick Overview
- 1#1: Epic Systems - Comprehensive EHR platform with advanced modules for infusion therapy scheduling, documentation, drug dispensing, and billing in infusion centers.
- 2#2: Cerner - Integrated health IT solution featuring PowerChart Oncology for managing patient flow, IV infusions, inventory, and regulatory compliance in infusion centers.
- 3#3: OncoEMR - Oncology-specific EHR tailored for infusion centers, offering chemotherapy order entry, treatment tracking, and seamless integration with lab and pharmacy systems.
- 4#4: MOSAIQ - Oncology information system that streamlines infusion therapy workflows, including protocol management, electronic prescribing, and real-time patient monitoring.
- 5#5: ARIA Oncology Information System - Advanced oncology platform supporting infusion center operations with treatment planning, automated dispensing, and interoperability for multi-site centers.
- 6#6: Nextech - Specialty EHR with customizable infusion workflows, inventory control for biologics, and revenue cycle management optimized for ambulatory infusion centers.
- 7#7: Allscripts - Flexible EHR and practice management system with infusion-specific tools for scheduling, clinical documentation, and HIPAA-compliant data handling.
- 8#8: athenahealth - Cloud-based EHR network providing infusion center features like patient engagement, automated billing, and analytics for therapy volume optimization.
- 9#9: NextGen Healthcare - Enterprise EHR with oncology and infusion modules for electronic health records, order management, and population health tracking in infusion settings.
- 10#10: eClinicalWorks - All-in-one EHR and PM solution with infusion therapy templates, telehealth integration, and reporting tools for efficient center management.
We selected and ranked these tools based on robust functionality addressing core infusion center needs (scheduling, documentation, inventory, billing), proven reliability, user-friendly design, and overall value, balancing performance with cost-effectiveness for diverse practice sizes and requirements.
Comparison Table
Infusion center software enhances patient care coordination and operational workflow, with top tools such as Epic Systems, Cerner, OncoEMR, MOSAIQ, and ARIA Oncology Information System. This comparison table outlines critical features, usability, and strengths to guide users in selecting the right solution for their facility’s specific requirements.
| # | Tool | Category | Overall | Features | Ease of Use | Value |
|---|---|---|---|---|---|---|
| 1 | Epic Systems Comprehensive EHR platform with advanced modules for infusion therapy scheduling, documentation, drug dispensing, and billing in infusion centers. | enterprise | 9.5/10 | 9.8/10 | 7.2/10 | 8.7/10 |
| 2 | Cerner Integrated health IT solution featuring PowerChart Oncology for managing patient flow, IV infusions, inventory, and regulatory compliance in infusion centers. | enterprise | 8.9/10 | 9.5/10 | 7.2/10 | 8.1/10 |
| 3 | OncoEMR Oncology-specific EHR tailored for infusion centers, offering chemotherapy order entry, treatment tracking, and seamless integration with lab and pharmacy systems. | specialized | 8.5/10 | 9.2/10 | 7.8/10 | 8.0/10 |
| 4 | MOSAIQ Oncology information system that streamlines infusion therapy workflows, including protocol management, electronic prescribing, and real-time patient monitoring. | specialized | 8.1/10 | 8.7/10 | 7.2/10 | 7.8/10 |
| 5 | ARIA Oncology Information System Advanced oncology platform supporting infusion center operations with treatment planning, automated dispensing, and interoperability for multi-site centers. | specialized | 8.4/10 | 9.2/10 | 7.1/10 | 7.8/10 |
| 6 | Nextech Specialty EHR with customizable infusion workflows, inventory control for biologics, and revenue cycle management optimized for ambulatory infusion centers. | specialized | 7.6/10 | 8.1/10 | 7.2/10 | 6.9/10 |
| 7 | Allscripts Flexible EHR and practice management system with infusion-specific tools for scheduling, clinical documentation, and HIPAA-compliant data handling. | enterprise | 7.3/10 | 8.1/10 | 6.4/10 | 6.9/10 |
| 8 | athenahealth Cloud-based EHR network providing infusion center features like patient engagement, automated billing, and analytics for therapy volume optimization. | enterprise | 7.6/10 | 8.0/10 | 7.0/10 | 6.8/10 |
| 9 | NextGen Healthcare Enterprise EHR with oncology and infusion modules for electronic health records, order management, and population health tracking in infusion settings. | enterprise | 8.1/10 | 8.4/10 | 7.6/10 | 7.8/10 |
| 10 | eClinicalWorks All-in-one EHR and PM solution with infusion therapy templates, telehealth integration, and reporting tools for efficient center management. | enterprise | 7.1/10 | 7.4/10 | 6.7/10 | 7.0/10 |
Comprehensive EHR platform with advanced modules for infusion therapy scheduling, documentation, drug dispensing, and billing in infusion centers.
Integrated health IT solution featuring PowerChart Oncology for managing patient flow, IV infusions, inventory, and regulatory compliance in infusion centers.
Oncology-specific EHR tailored for infusion centers, offering chemotherapy order entry, treatment tracking, and seamless integration with lab and pharmacy systems.
Oncology information system that streamlines infusion therapy workflows, including protocol management, electronic prescribing, and real-time patient monitoring.
Advanced oncology platform supporting infusion center operations with treatment planning, automated dispensing, and interoperability for multi-site centers.
Specialty EHR with customizable infusion workflows, inventory control for biologics, and revenue cycle management optimized for ambulatory infusion centers.
Flexible EHR and practice management system with infusion-specific tools for scheduling, clinical documentation, and HIPAA-compliant data handling.
Cloud-based EHR network providing infusion center features like patient engagement, automated billing, and analytics for therapy volume optimization.
Enterprise EHR with oncology and infusion modules for electronic health records, order management, and population health tracking in infusion settings.
All-in-one EHR and PM solution with infusion therapy templates, telehealth integration, and reporting tools for efficient center management.
Epic Systems
enterpriseComprehensive EHR platform with advanced modules for infusion therapy scheduling, documentation, drug dispensing, and billing in infusion centers.
Seamless integration with smart infusion pumps and auto-programming to reduce errors and enhance safety during administration.
Epic Systems offers a comprehensive EHR platform with specialized modules like Beacon Oncology and Willow Pharmacy tailored for infusion centers, enabling end-to-end management of patient scheduling, order entry, medication administration, and billing for IV therapies. It supports integration with smart infusion pumps, real-time documentation, clinical decision support, and regulatory compliance reporting. As the market leader, Epic's solution scales seamlessly for high-volume environments while ensuring interoperability with other healthcare systems.
Pros
- Unmatched integration with EHR, pumps, and lab systems
- Robust customization and analytics for infusion workflows
- Proven reliability and 24/7 support in enterprise settings
Cons
- Steep learning curve and lengthy implementation (often 1-2 years)
- High upfront and ongoing costs
- Less ideal for small standalone infusion centers
Best For
Large hospitals, academic medical centers, and multi-site infusion networks requiring enterprise-grade scalability and integration.
Pricing
Custom enterprise licensing starting at $1M+ for implementation, plus per-user fees and ongoing maintenance; pricing not publicly listed.
Cerner
enterpriseIntegrated health IT solution featuring PowerChart Oncology for managing patient flow, IV infusions, inventory, and regulatory compliance in infusion centers.
Closed-loop integration with infusion pumps for automated programming and safety checks, reducing medication errors.
Cerner, now part of Oracle Health, offers a robust EHR platform with specialized modules for infusion centers, including scheduling, medication order management, electronic infusion documentation, and integration with smart pumps. It streamlines workflows for chemotherapy, IV therapies, and biologics administration while ensuring compliance with oncology and regulatory standards. The system provides advanced analytics, billing automation, and interoperability with hospital-wide systems for comprehensive patient care.
Pros
- Seamless integration with enterprise EHR and smart infusion pumps for closed-loop medication management
- Comprehensive clinical decision support and protocol libraries tailored for oncology infusions
- Robust reporting, analytics, and compliance tools for regulatory adherence
Cons
- Steep learning curve and complex user interface requiring extensive training
- High implementation costs and long deployment timelines
- Custom pricing often prohibitive for smaller infusion centers
Best For
Large hospitals and health systems with high-volume infusion centers needing deep integration with existing EHR infrastructure.
Pricing
Enterprise-level custom pricing, typically starting at $1M+ annually based on modules, users, and implementation scope; no public tiered plans.
OncoEMR
specializedOncology-specific EHR tailored for infusion centers, offering chemotherapy order entry, treatment tracking, and seamless integration with lab and pharmacy systems.
Automated NCCN-compliant treatment planning with built-in regimen editor and dosing calculators
OncoEMR is a cloud-based, oncology-specific electronic health record (EHR) system tailored for cancer care practices, including infusion centers. It provides comprehensive tools for managing infusion therapies, such as automated chemotherapy regimen building, real-time drug inventory tracking, and precise dosing calculations compliant with NCCN guidelines. The platform integrates clinical documentation, scheduling, billing, and reporting to streamline workflows from treatment planning to reimbursement.
Pros
- Extensive oncology protocol library with auto-dosing and treatment pathways
- Seamless integration of EHR, billing, and infusion management
- Real-time inventory and chair-side documentation for efficient infusions
Cons
- Steep learning curve due to oncology specialization
- Custom pricing can be high for smaller practices
- Limited flexibility for non-oncology infusion therapies
Best For
Mid-sized oncology practices with dedicated infusion centers needing specialized EMR capabilities.
Pricing
Custom subscription pricing based on practice size and users; typically $400-$800 per user/month with implementation fees.
MOSAIQ
specializedOncology information system that streamlines infusion therapy workflows, including protocol management, electronic prescribing, and real-time patient monitoring.
Integrated radiation-medical oncology workflow that unifies patient data and treatment delivery across modalities
MOSAIQ by Elekta is a comprehensive oncology information system (OIS) that extends to infusion center management, handling chemotherapy ordering, verification, administration documentation, and billing workflows. It integrates patient data across radiation and medical oncology, ensuring seamless coordination for multi-disciplinary cancer care. While primarily designed for radiation therapy, its medical oncology module supports infusion centers with safety protocols and regulatory compliance tools.
Pros
- Robust integration with EHRs and treatment planning systems
- Advanced safety checks like closed-loop verification for infusions
- Scalable for enterprise-level oncology networks
Cons
- Steep learning curve and complex interface
- High implementation and customization costs
- Less specialized for standalone infusion centers without radiation oncology
Best For
Large multi-disciplinary oncology centers managing both radiation therapy and infusion services.
Pricing
Enterprise licensing with custom pricing; typically $100K+ annually per site, including implementation fees.
ARIA Oncology Information System
specializedAdvanced oncology platform supporting infusion center operations with treatment planning, automated dispensing, and interoperability for multi-site centers.
Protocol-driven closed-loop ordering that links chemo regimens directly to pharmacy compounding and infusion pump programming for error reduction.
The ARIA Oncology Information System from Siemens Healthineers is a comprehensive enterprise platform tailored for oncology care, including robust support for infusion centers through chemotherapy regimen management, drug ordering, and administration workflows. It integrates electronic health records, treatment planning, and billing to streamline operations in medical oncology settings. Key capabilities include protocol-driven orders, automated safety checks for high-risk infusions, and real-time inventory tracking for hazardous drugs.
Pros
- Seamless integration with EMR and oncology treatment planning systems
- Advanced safety features like automated dose calculations and allergy checks for chemo infusions
- Comprehensive reporting and analytics for compliance and outcomes tracking
Cons
- Steep learning curve due to its enterprise-level complexity
- High implementation and customization costs
- Less intuitive for non-oncology staff in standalone infusion centers
Best For
Large hospitals or comprehensive cancer centers managing both radiation and medical oncology infusions with high patient volumes.
Pricing
Enterprise licensing with custom pricing; typically $500K+ annually for mid-sized implementations, plus setup fees.
Nextech
specializedSpecialty EHR with customizable infusion workflows, inventory control for biologics, and revenue cycle management optimized for ambulatory infusion centers.
Infusion-specific inventory and waste tracking integrated with EHR for precise compliance and reimbursement
Nextech is a specialty-focused EHR and practice management software that supports infusion centers, particularly in dermatology, rheumatology, and ophthalmology practices administering IV therapies. It offers tools for scheduling, infusion documentation, drug inventory management, and complex billing with J-codes and waste tracking. The platform integrates with practice workflows to ensure compliance and efficiency in ambulatory infusion settings.
Pros
- Specialty-specific templates for infusion charting and protocols
- Strong inventory management for high-cost biologics and drugs
- Advanced revenue cycle management with infusion-specific billing
Cons
- Steep learning curve due to specialty customization
- Pricing is enterprise-level and not transparent
- Limited standalone use outside integrated specialty practices
Best For
Infusion centers embedded within dermatology, rheumatology, or ophthalmology practices needing comprehensive EHR integration.
Pricing
Custom quote-based pricing, typically $450-$700 per provider per month plus implementation fees.
Allscripts
enterpriseFlexible EHR and practice management system with infusion-specific tools for scheduling, clinical documentation, and HIPAA-compliant data handling.
Advanced chemotherapy order entry and infusion pump integration for precise dosing and safety checks
Allscripts provides a robust electronic health record (EHR) platform with modules tailored for ambulatory care and oncology, enabling infusion centers to manage patient scheduling, treatment protocols, drug ordering, administration documentation, and billing. It integrates infusion-specific workflows like chemotherapy order entry and inventory tracking within a broader healthcare IT ecosystem. While not exclusively an infusion center solution, its scalability supports high-volume specialty infusion operations.
Pros
- Seamless integration with hospital EHR systems and pharmacies
- Strong compliance tools for oncology and infusion protocols (e.g., ASCO guidelines)
- Comprehensive billing and revenue cycle management
Cons
- Complex interface with steep learning curve for staff
- High implementation and customization costs
- Less specialized for standalone infusion centers compared to niche tools
Best For
Large multi-site infusion centers or oncology practices integrated with broader hospital systems seeking enterprise-level EHR functionality.
Pricing
Enterprise pricing starts at $500+ per provider/month; custom quotes based on modules, users, and implementation (often $100K+ upfront).
athenahealth
enterpriseCloud-based EHR network providing infusion center features like patient engagement, automated billing, and analytics for therapy volume optimization.
AI-driven revenue integrity suite that proactively identifies and resolves billing errors for complex infusion reimbursements
athenahealth's athenaOne is a comprehensive cloud-based EHR and practice management platform that supports clinical workflows, scheduling, billing, and patient engagement for various medical specialties. For infusion centers, it offers customizable templates for infusion documentation, drug order entry, inventory management, and revenue cycle tools to handle complex reimbursement for therapies like chemotherapy or biologics. While not exclusively designed for infusions, its interoperability and scalability make it suitable for practices integrating infusion services with broader care delivery.
Pros
- Strong revenue cycle management with automated claim scrubbing for infusion billing
- Cloud-based accessibility with mobile apps for on-the-go charting
- Excellent interoperability via the athenahealth Network for data exchange
Cons
- High implementation and ongoing costs
- Steep learning curve for non-standard infusion workflows
- Requires customization or add-ons for advanced infusion-specific features like pump integration
Best For
Medium to large infusion centers or multi-specialty practices needing robust EHR integration and billing automation.
Pricing
Quote-based pricing; typically $200-$450 per provider/month plus implementation fees and add-ons.
NextGen Healthcare
enterpriseEnterprise EHR with oncology and infusion modules for electronic health records, order management, and population health tracking in infusion settings.
Advanced infusion billing module with automated time-tracking and multi-drug protocol support for precise reimbursement.
NextGen Healthcare is a comprehensive enterprise EHR and practice management platform designed for ambulatory and specialty practices, including infusion centers, offering tools for patient scheduling, clinical documentation, and billing. It supports infusion-specific workflows like time-based HCPCS coding, drug order entry, inventory tracking via integrations, and regulatory compliance for IV therapies such as chemotherapy and biologics. The system emphasizes interoperability and scalability for larger organizations handling high-volume infusions.
Pros
- Robust billing engine handles complex infusion codes (J-codes, time tracking)
- Scalable for enterprise-level infusion centers with strong interoperability
- Integrated clinical decision support and e-prescribing for drug management
Cons
- Steep learning curve and dated interface requiring extensive training
- High implementation costs and customization needs for infusion workflows
- Less intuitive for small standalone infusion centers compared to niche tools
Best For
Mid-to-large infusion centers or multi-specialty practices within healthcare networks needing a full-featured EHR with advanced billing.
Pricing
Custom enterprise pricing; typically $400–$700 per provider/month plus significant implementation fees ($50K+).
eClinicalWorks
enterpriseAll-in-one EHR and PM solution with infusion therapy templates, telehealth integration, and reporting tools for efficient center management.
Sunoh.ai integration for AI-driven ambient clinical documentation to accelerate infusion charting and note completion
eClinicalWorks is a comprehensive cloud-based EHR and practice management platform that supports infusion centers with scheduling, clinical documentation, medication order management, and billing workflows tailored for ambulatory infusion therapies like chemotherapy and IV biologics. It includes specialty templates for oncology and infusion protocols, along with patient portals and revenue cycle tools to ensure compliance and efficient reimbursement. While versatile for integrated practices, it requires customization for optimal infusion-specific use.
Pros
- Integrated EHR and practice management for streamlined workflows
- Strong revenue cycle and billing capabilities optimized for infusion codes
- Customizable order sets and templates for infusion protocols
Cons
- Steep learning curve and complex interface requiring extensive training
- Limited native integrations with infusion pumps and chairs
- Occasional reports of slow customer support and system downtime
Best For
Mid-sized infusion centers affiliated with multi-specialty practices seeking a full-suite EHR with billing integration.
Pricing
Quote-based pricing, typically $445-$700 per provider per month plus setup fees and add-ons for advanced modules.
Conclusion
The top three infusion center software solutions showcased a blend of specialized features, with Epic Systems leading as the most comprehensive choice, Cerner excelling in integrated, regulatory-focused workflows, and OncoEMR offering tailored oncology support. Each tool addresses unique needs, ensuring infusion centers can find optimal fits whether prioritizing advanced modules, interoperability, or specialized treatment tracking.
Begin with Epic Systems to unlock streamlined scheduling, documentation, and billing—its robust capabilities make it the ideal starting point for enhancing infusion center efficiency and care delivery.
Tools Reviewed
All tools were independently evaluated for this comparison
