Top 10 Best Healthcare Help Desk Software of 2026

Zendesk is a robust customer service platform that streamlines help desk operations through ticketing, live chat, email, and self-service portals. In healthcare, it supports patient support for inquiries, appointment management, billing assistance, and compliance needs with HIPAA-eligible Enterprise plans and Business Associate Agreements (BAA). Its AI-powered tools and extensive integrations with EHR systems like Epic and Cerner enable efficient, scalable help desk solutions for providers.

Freshservice is a cloud-based IT service management (ITSM) platform that provides comprehensive help desk functionality, including ticketing, asset management, and automation workflows, built on ITIL best practices. For healthcare help desks, it excels in managing IT support for clinical staff, handling incidents related to EHR systems, medical devices, and network issues while ensuring compliance through HIPAA-eligible plans. Its self-service portal and AI-driven insights reduce resolution times, making it suitable for hospitals and clinics needing reliable service desk operations.

ServiceNow is a comprehensive cloud-based platform primarily known for IT service management (ITSM), which can be customized for healthcare help desk operations to handle incident tickets, service requests, and employee support in clinical environments. It leverages the Now Platform to automate workflows, integrate with EHR systems like Epic, and ensure HIPAA compliance for secure data handling. Key healthcare adaptations include patient service portals, virtual agents for self-service, and analytics for optimizing help desk performance.

Jira Service Management is a robust IT service management (ITSM) platform from Atlassian designed for handling service requests, incidents, and changes through customizable ticketing workflows. In a healthcare help desk context, it excels at managing IT support for staff, tracking SLAs for critical response times, and integrating with monitoring tools to minimize downtime in clinical environments. It supports asset management and reporting to ensure compliance with operational standards, though it requires configuration for healthcare-specific needs like HIPAA workflows.

ServiceDesk Plus by ManageEngine is a versatile IT service management (ITSM) platform designed for help desk operations, including ticketing, asset management, and workflow automation, with features adaptable for healthcare environments. It supports HIPAA compliance through on-premises or secure cloud deployments, enabling tracking of medical equipment, incident resolution for clinical IT issues, and self-service portals for healthcare staff. The software excels in providing customizable business rules and reporting to streamline healthcare help desk processes like patient system support and compliance audits.

SysAI d is a robust IT service management (ITSM) platform designed for help desk operations, offering ticketing, asset management, automation, and self-service portals. In healthcare settings, it supports HIPAA compliance through secure data handling, audit trails, and customizable workflows for IT support of clinical systems and staff devices. It enables efficient resolution of help desk tickets while integrating with healthcare-specific tools for streamlined operations.

InvGate Service Desk is a robust IT service management (ITSM) platform that centralizes ticketing, asset management, and automation for help desk operations. It supports ITIL best practices with features like SLA management, self-service portals, and AI-driven insights, making it suitable for healthcare environments needing efficient IT support for clinical and administrative teams. While not natively HIPAA-certified, it offers strong security features, audit trails, and customizable workflows to handle sensitive healthcare data and compliance requirements.

HaloITSM is a cloud-based IT Service Management (ITSM) platform that delivers comprehensive help desk capabilities, including ticketing, asset management, automation, and self-service portals, making it suitable for healthcare IT support. It supports customizable workflows, SLAs, and reporting to handle incidents efficiently in fast-paced healthcare environments like hospitals and clinics. While not healthcare-specific, its ITIL-aligned features and compliance tools (SOC 2) allow adaptation for HIPAA workflows and medical device tracking.

Zoho Desk is a versatile cloud-based help desk platform that streamlines patient support tickets, inquiries, and service requests for healthcare organizations through multi-channel communication including email, chat, phone, and social media. It offers automation, AI-driven insights via Zia, SLAs, and customizable workflows to manage healthcare-specific support efficiently. With HIPAA compliance available on higher plans via a Business Associate Agreement, it supports secure handling of sensitive patient data while integrating with general CRM and telephony tools.

Ivanti Service Manager is a robust IT service management (ITSM) platform designed for handling help desk operations, including incident management, service requests, and asset tracking, which can be adapted for healthcare environments. It offers customizable workflows, self-service portals, and automation to streamline IT support in hospitals and clinics. While ITIL-aligned and scalable, it requires configuration for healthcare-specific needs like HIPAA compliance.