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Healthcare Medicine

Top 10 Best Health Care Billing Software of 2026

Discover top 10 best health care billing software. Compare features, find the right fit for your practice. Start optimizing your billing process today.

Alexander Schmidt

Alexander Schmidt

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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Health care billing software is indispensable for optimizing revenue cycles and streamlining administrative workflows, making it critical for providers to select a tool that aligns with their unique needs. From automated claims processing to integration with electronic health records (EHR), the options highlighted below cater to diverse practice sizes and operational priorities, ensuring efficient financial management.

Quick Overview

  1. 1#1: Kareo - Cloud-based medical billing and practice management software that streamlines claims processing and revenue cycle management for healthcare providers.
  2. 2#2: AdvancedMD - Comprehensive billing solution integrated with EHR and practice management to optimize reimbursements and reduce denials.
  3. 3#3: athenahealth - Integrated EHR and revenue cycle management platform with advanced billing features for efficient claims submission and payment posting.
  4. 4#4: DrChrono - Mobile-first EHR and billing software that automates claims, eligibility checks, and patient payments.
  5. 5#5: NextGen Healthcare - Enterprise-grade practice management and billing system with robust analytics for large healthcare organizations.
  6. 6#6: eClinicalWorks - All-in-one EHR platform with integrated billing tools for seamless claims management and reporting.
  7. 7#7: Greenway Health - Revenue cycle management software focused on accurate medical billing and denial prevention.
  8. 8#8: CureMD - Cloud-based EHR and billing solution offering automated claims processing and financial reporting.
  9. 9#9: Practice Fusion - Free EHR with integrated billing features for electronic claims submission and practice efficiency.
  10. 10#10: CollaborateMD - Web-based medical billing software designed for clearinghouse integration and revenue optimization.

Tools were evaluated based on key metrics such as feature robustness (including denial management and patient payment integration), user experience, and value, with a focus on platforms that deliver consistent performance and adaptability for modern health care environments.

Comparison Table

This comparison table explores top healthcare billing software tools, including Kareo, AdvancedMD, athenahealth, DrChrono, NextGen Healthcare, and more, helping readers evaluate key features, pricing, and usability to find the best fit for their practice.

1Kareo logo9.4/10

Cloud-based medical billing and practice management software that streamlines claims processing and revenue cycle management for healthcare providers.

Features
9.6/10
Ease
8.9/10
Value
9.2/10
2AdvancedMD logo9.1/10

Comprehensive billing solution integrated with EHR and practice management to optimize reimbursements and reduce denials.

Features
9.4/10
Ease
8.6/10
Value
8.2/10

Integrated EHR and revenue cycle management platform with advanced billing features for efficient claims submission and payment posting.

Features
9.3/10
Ease
8.1/10
Value
8.2/10
4DrChrono logo8.4/10

Mobile-first EHR and billing software that automates claims, eligibility checks, and patient payments.

Features
9.1/10
Ease
7.6/10
Value
7.9/10

Enterprise-grade practice management and billing system with robust analytics for large healthcare organizations.

Features
8.7/10
Ease
7.4/10
Value
7.9/10

All-in-one EHR platform with integrated billing tools for seamless claims management and reporting.

Features
8.2/10
Ease
6.4/10
Value
7.0/10

Revenue cycle management software focused on accurate medical billing and denial prevention.

Features
8.4/10
Ease
7.3/10
Value
7.7/10
8CureMD logo8.1/10

Cloud-based EHR and billing solution offering automated claims processing and financial reporting.

Features
8.6/10
Ease
7.4/10
Value
7.9/10

Free EHR with integrated billing features for electronic claims submission and practice efficiency.

Features
6.5/10
Ease
8.0/10
Value
9.3/10

Web-based medical billing software designed for clearinghouse integration and revenue optimization.

Features
8.1/10
Ease
7.7/10
Value
8.4/10
1
Kareo logo

Kareo

specialized

Cloud-based medical billing and practice management software that streamlines claims processing and revenue cycle management for healthcare providers.

Overall Rating9.4/10
Features
9.6/10
Ease of Use
8.9/10
Value
9.2/10
Standout Feature

Kareo Intelligence AI-driven analytics for real-time revenue cycle insights and automated optimization recommendations

Kareo is a cloud-based healthcare platform specializing in revenue cycle management, medical billing, EHR, and practice management for independent practices. It automates claims processing, denial management, and patient payments while integrating seamlessly with major clearinghouses and EHR systems. Kareo also provides analytics tools like Kareo Intelligence to optimize reimbursements and operational efficiency.

Pros

  • Comprehensive revenue cycle management with claims scrubbing and denial prevention
  • Integrated EHR and patient portal for streamlined workflows
  • Robust analytics and reporting for revenue optimization

Cons

  • Higher pricing tiers can be expensive for very small practices
  • Initial setup and data migration may require time and support
  • Some advanced customizations need professional services

Best For

Independent medical practices and small to mid-sized groups needing an all-in-one billing and practice management solution.

Pricing

Starts at $110/provider/month for billing-only; full suite plans range from $160-$300+/provider/month; volume discounts and custom quotes available.

Visit Kareokareo.com
2
AdvancedMD logo

AdvancedMD

enterprise

Comprehensive billing solution integrated with EHR and practice management to optimize reimbursements and reduce denials.

Overall Rating9.1/10
Features
9.4/10
Ease of Use
8.6/10
Value
8.2/10
Standout Feature

AI-powered claims scrubber that prevents denials upfront with 99% accuracy

AdvancedMD is a comprehensive cloud-based platform offering integrated electronic health records (EHR), practice management, and revenue cycle management (RCM) solutions specifically designed for healthcare providers. Its billing software excels in automating claims submission, scrubbing for errors, denial management, and patient payment processing to maximize reimbursements. With seamless integration across clinical, financial, and administrative workflows, it supports specialties from solo practices to large enterprises.

Pros

  • Robust RCM with 98%+ clean claims rate and automated denial workflows
  • Seamless EHR-billing integration for accurate coding and compliance
  • Advanced analytics and reporting for financial insights

Cons

  • High pricing can be prohibitive for small practices
  • Steep initial learning curve and setup time
  • Customer support response times vary

Best For

Mid-sized to large medical practices seeking an all-in-one platform with enterprise-grade billing automation.

Pricing

Custom quotes starting at $400-$700 per provider/month for core billing features, scaling with users and modules.

Visit AdvancedMDadvancedmd.com
3
athenahealth logo

athenahealth

enterprise

Integrated EHR and revenue cycle management platform with advanced billing features for efficient claims submission and payment posting.

Overall Rating8.7/10
Features
9.3/10
Ease of Use
8.1/10
Value
8.2/10
Standout Feature

AI-driven Intelligent Revenue Cycle Management that proactively identifies and resolves billing issues before they impact cash flow

athenahealth offers athenaOne, a cloud-based platform that integrates electronic health records (EHR), practice management, and comprehensive revenue cycle management (RCM) for healthcare billing. It automates claims processing, denial management, payment posting, and patient collections with AI-driven insights to optimize revenue. The solution supports interoperability with other systems and provides robust analytics for financial performance tracking.

Pros

  • Advanced RCM automation including AI-powered denial prevention and predictive analytics
  • Seamless cloud-based access with 99.9% uptime and mobile compatibility
  • Strong interoperability and compliance with HIPAA and MIPS reporting

Cons

  • High implementation costs and lengthy onboarding process
  • Pricing can be prohibitive for small practices
  • Steep learning curve for non-technical users

Best For

Medium to large medical practices or multi-specialty groups needing integrated EHR and scalable billing solutions.

Pricing

Custom subscription pricing starting at $300-$500 per provider per month, including EHR, PM, and billing; additional fees for implementation and add-ons.

Visit athenahealthathenahealth.com
4
DrChrono logo

DrChrono

specialized

Mobile-first EHR and billing software that automates claims, eligibility checks, and patient payments.

Overall Rating8.4/10
Features
9.1/10
Ease of Use
7.6/10
Value
7.9/10
Standout Feature

Native iPad and iPhone apps enabling full billing workflows directly from mobile devices during patient encounters

DrChrono is a cloud-based electronic health record (EHR) and practice management platform with integrated healthcare billing capabilities designed for medical practices. It streamlines revenue cycle management through features like automated claims submission to major clearinghouses, electronic remittance advice (ERA) posting, denial management, and patient payment processing. The software supports eligibility verification, superbilling, and customizable billing rules, making it suitable for specialty practices seeking an all-in-one solution.

Pros

  • Seamless EHR-billing integration reduces errors and speeds up workflows
  • Mobile-first design with native iOS apps for on-the-go billing
  • Advanced revenue cycle tools including auto-posting and denial scrubbing

Cons

  • Steep learning curve for new users due to extensive customization options
  • Higher pricing may not suit very small practices
  • Customer support response times can be inconsistent

Best For

Small to mid-sized specialty practices needing integrated EHR billing with strong mobile accessibility.

Pricing

Starts at $199/provider/month for Essentials plan; Professional ($339), Premium ($439), and Enterprise (custom) tiers available, plus one-time setup fees and per-claim costs.

Visit DrChronodrchrono.com
5
NextGen Healthcare logo

NextGen Healthcare

enterprise

Enterprise-grade practice management and billing system with robust analytics for large healthcare organizations.

Overall Rating8.2/10
Features
8.7/10
Ease of Use
7.4/10
Value
7.9/10
Standout Feature

Precision Claims scrubbing engine with AI-driven error detection and denial prediction

NextGen Healthcare provides a comprehensive electronic health record (EHR) and revenue cycle management (RCM) platform tailored for ambulatory practices, with robust medical billing capabilities including claims submission, scrubbing, and denial management. The software integrates clinical documentation with financial workflows to automate charge capture, eligibility verification, and payment posting. It supports specialties through customizable templates and analytics for optimizing reimbursements and reducing administrative burdens.

Pros

  • Deep integration between EHR and billing for streamlined workflows
  • Advanced denial management and predictive analytics tools
  • Customizable reporting and compliance features for various specialties

Cons

  • Steep learning curve for new users due to complex interface
  • High implementation and customization costs
  • Occasional performance lags in large-scale deployments

Best For

Mid-to-large ambulatory practices and specialty groups needing integrated EHR and advanced revenue cycle management.

Pricing

Custom quote-based pricing, typically $500-$2,000+ per provider/month depending on modules, users, and practice size; includes implementation fees.

6
eClinicalWorks logo

eClinicalWorks

enterprise

All-in-one EHR platform with integrated billing tools for seamless claims management and reporting.

Overall Rating7.3/10
Features
8.2/10
Ease of Use
6.4/10
Value
7.0/10
Standout Feature

Predictive analytics in revenue cycle management for identifying denial risks and optimizing cash flow

eClinicalWorks is a comprehensive electronic health record (EHR) and practice management platform with robust healthcare billing features, including revenue cycle management (RCM), electronic claims submission, and denial management. It automates billing workflows, supports eligibility verification, and provides detailed financial reporting to optimize reimbursements. Integrated with clinical tools, it enables seamless data flow from patient encounters to payment collection for various practice sizes.

Pros

  • Integrated EHR and RCM for streamlined workflows
  • Advanced claims scrubbing and denial management tools
  • Scalable for multi-location practices with strong compliance features

Cons

  • Clunky user interface with steep learning curve
  • Frequent complaints about customer support response times
  • Limited customization options without additional costs

Best For

Medium to large healthcare practices needing an integrated EHR and billing solution for complex revenue cycles.

Pricing

Custom quotes starting at $450-$800 per provider per month, plus implementation fees ($10K+) and per-user add-ons.

Visit eClinicalWorkseclinicalworks.com
7
Greenway Health logo

Greenway Health

specialized

Revenue cycle management software focused on accurate medical billing and denial prevention.

Overall Rating7.9/10
Features
8.4/10
Ease of Use
7.3/10
Value
7.7/10
Standout Feature

Predictive denial management with AI-driven analytics to proactively identify and prevent claim rejections

Greenway Health offers Intergy, a comprehensive EHR and practice management platform with robust healthcare billing capabilities designed for ambulatory practices. It streamlines revenue cycle management through automated claims processing, denial management, patient eligibility verification, and financial reporting. The software integrates seamlessly with EHR to reduce errors and accelerate reimbursements while ensuring HIPAA compliance and ONC certification.

Pros

  • Integrated EHR and billing for efficient workflows
  • Advanced denial management and claims scrubbing
  • Customizable reporting and analytics for revenue insights

Cons

  • Steep learning curve for new users
  • Custom pricing lacks transparency
  • Customer support response times can vary

Best For

Mid-sized ambulatory practices needing an all-in-one EHR and billing solution for multiple specialties.

Pricing

Custom pricing based on practice size, providers, and modules; typically $300-$600 per provider/month on a subscription model.

Visit Greenway Healthgreenwayhealth.com
8
CureMD logo

CureMD

specialized

Cloud-based EHR and billing solution offering automated claims processing and financial reporting.

Overall Rating8.1/10
Features
8.6/10
Ease of Use
7.4/10
Value
7.9/10
Standout Feature

AI-driven claims intelligence for predictive denial prevention and automated resubmissions

CureMD is a cloud-based healthcare platform with robust medical billing capabilities integrated into its EHR and practice management suite, enabling efficient revenue cycle management for medical practices. It supports electronic claims submission, automated scrubbing, denial management, eligibility verification, and detailed financial reporting to maximize reimbursements. Designed for specialty practices, it streamlines billing workflows while ensuring HIPAA compliance and seamless interoperability with clearinghouses and payers.

Pros

  • Comprehensive revenue cycle management with claims scrubbing and denial tracking
  • Seamless integration with EHR for accurate charge capture
  • Customizable reporting and analytics for financial insights

Cons

  • Steep learning curve for new users due to extensive features
  • Custom pricing lacks transparency and can be costly for small practices
  • Customer support response times can be inconsistent

Best For

Mid-sized specialty practices seeking an integrated EHR-billing solution for optimized reimbursements.

Pricing

Custom quote-based pricing, typically starting at $300-$500 per provider per month, with additional fees for advanced modules or billing services.

Visit CureMDcuremd.com
9
Practice Fusion logo

Practice Fusion

specialized

Free EHR with integrated billing features for electronic claims submission and practice efficiency.

Overall Rating7.1/10
Features
6.5/10
Ease of Use
8.0/10
Value
9.3/10
Standout Feature

Free, fully integrated EHR with automated superbill generation from encounter notes

Practice Fusion is a cloud-based electronic health records (EHR) platform with integrated billing tools designed for small to medium-sized medical practices. It supports encounter documentation, superbill generation, charge capture, and basic claims management, allowing providers to handle billing workflows alongside clinical charting. While not a standalone billing solution, it streamlines administrative tasks through its all-in-one interface and third-party integrations.

Pros

  • Free core platform with no subscription fees for basic EHR and billing
  • Seamless integration between clinical documentation and billing
  • Cloud-based with mobile access for on-the-go charge entry
  • ONC-certified for meaningful use and e-prescribing

Cons

  • Lacks direct payer claims submission and full revenue cycle management
  • Billing features are basic, relying on exports or third-party partners
  • Limited customization for complex billing scenarios
  • Occasional user complaints about interface glitches and support response times

Best For

Solo practitioners and small clinics needing affordable, integrated EHR with straightforward billing for superbills and basic charges.

Pricing

Free for core EHR and billing features; paid add-ons for premium support, advanced integrations, and practice management ($149-$299/month per provider).

Visit Practice Fusionpracticefusion.com
10
CollaborateMD logo

CollaborateMD

specialized

Web-based medical billing software designed for clearinghouse integration and revenue optimization.

Overall Rating7.9/10
Features
8.1/10
Ease of Use
7.7/10
Value
8.4/10
Standout Feature

Built-in claims scrubbing engine that automatically detects and corrects errors before submission

CollaborateMD is a web-based medical billing software tailored for healthcare practices, focusing on revenue cycle management through electronic claims submission, scrubbing, and denial management. It supports patient billing, appointment scheduling, reporting, and integrates with popular EHR systems and clearinghouses. The platform emphasizes efficiency for small to mid-sized practices, helping to reduce claim rejections and accelerate payments.

Pros

  • Robust claims scrubbing and editing tools for high first-pass acceptance rates
  • Affordable pricing scalable by claims volume
  • Strong integration with EHRs and clearinghouses like Availity

Cons

  • Limited advanced analytics and customization options
  • Occasional reports of slow customer support response times
  • Interface can feel dated compared to modern competitors

Best For

Small to medium-sized medical practices seeking cost-effective billing without complex enterprise needs.

Pricing

Starts at $119/month for up to 100 claims, scaling to $489/month for 1,500+ claims; includes setup fees and per-claim options.

Visit CollaborateMDcollaboratemd.com

Conclusion

Among the top tools in health care billing, Kareo, AdvancedMD, and athenahealth rise to the forefront—each with distinct strengths to enhance revenue cycle management. Kareo leads with its streamlined claims processing and cloud-based design, AdvancedMD shines through seamless EHR integration, and athenahealth impresses with robust revenue cycle features. Together, these platforms set a standard for efficiency, empowering providers to focus on patient care without compromising billing accuracy.

Kareo logo
Our Top Pick
Kareo

Ready to elevate your practice? Start with Kareo today and discover why it’s the top choice for simplifying billing, optimizing reimbursements, and driving success.