Top 10 Best Certificate Of Analysis Software of 2026

LabWare LIMS is a comprehensive Laboratory Information Management System that excels as a Certificate of Analysis (CoA) software solution by automating the generation, review, and distribution of CoAs through integrated sample tracking, result management, and customizable reporting templates. It supports end-to-end workflows from sample login to final CoA approval, ensuring compliance with regulations like FDA 21 CFR Part 11, ISO 17025, and GMP. With seamless instrument integration and real-time data capture, it minimizes errors and accelerates release processes for industries like pharmaceuticals, chemicals, and food testing.

STARLIMS is a comprehensive Laboratory Information Management System (LIMS) designed for regulated industries like pharmaceuticals, biotechnology, and food testing. It excels in automating laboratory workflows, including sample tracking, instrument integration, and the generation of Certificates of Analysis (CoA) with built-in compliance features. The software ensures accurate, traceable reporting by pulling real-time test data, performing calculations, and producing customizable, electronically signed CoAs that meet standards like FDA 21 CFR Part 11 and ISO 17025.

Thermo Scientific SampleManager LIMS is a comprehensive laboratory information management system (LIMS) designed to streamline lab workflows, with robust capabilities for automated Certificate of Analysis (CoA) generation. It captures real-time data from instruments, applies predefined templates, and ensures regulatory compliance through features like electronic signatures and audit trails. Ideal for regulated industries, it supports end-to-end sample management from intake to CoA release, reducing manual errors and accelerating reporting.

LabVantage is an enterprise-grade Laboratory Information Management System (LIMS) tailored for regulated industries like pharmaceuticals, biotech, and chemicals. It streamlines lab workflows from sample accessioning to result reporting, with robust support for generating Certificates of Analysis (CoA) through automated data aggregation and compliance-checked templates. The platform ensures data integrity with features like audit trails and electronic signatures, making it suitable for high-volume testing environments.

MasterControl is a comprehensive enterprise quality management system (QMS) designed for regulated industries like pharmaceuticals, biotechnology, and medical devices, with robust support for Certificate of Analysis (COA) generation through its manufacturing control and electronic batch records modules. It automates the collection of batch data, lab results, and approvals to produce compliant COAs, ensuring traceability and regulatory adherence to standards such as FDA 21 CFR Part 11 and ISO 13485. The platform integrates with LIMS, ERP, and other systems for seamless data flow, making it suitable for complex manufacturing environments.

EtQ Reliance is a comprehensive enterprise Quality Management System (QMS) platform that supports Certificate of Analysis (COA) management through configurable workflows, automated data collection from labs, and compliant reporting. It enables organizations to generate, review, approve, and distribute COAs while maintaining full audit trails and electronic signatures for regulatory compliance. Primarily targeted at regulated industries like pharmaceuticals, food & beverage, and manufacturing, it integrates COA processes into broader quality operations including supplier management and non-conformances.

Dotmatics is a comprehensive scientific informatics platform that integrates ELN, LIMS, and analytics tools to support Certificate of Analysis (CoA) generation in regulated environments like pharma and biotech. It automates data capture from instruments, ensures compliance with standards such as 21 CFR Part 11, and enables customizable CoA templates with real-time data integration. While powerful for enterprise workflows, it excels in connecting CoA processes to broader R&D data management.

LabLynx LIMS is a comprehensive laboratory information management system designed to manage the entire lab workflow, from sample accessioning to reporting. For Certificates of Analysis (CoA), it provides automated generation of customizable CoA reports directly from test results, with support for electronic signatures and export formats like PDF and XML. It ensures compliance with standards such as ISO 17025, FDA 21 CFR Part 11, and GLP, making it suitable for regulated industries like pharmaceuticals, food, and environmental testing.

Benchling is a comprehensive cloud-based platform primarily designed for life sciences R&D, offering tools for experiment design, sample tracking, and molecular biology workflows. For Certificate of Analysis (COA) purposes, it provides robust manufacturing and quality management modules that enable batch record management, automated data collection from instruments, and customizable COA report generation with electronic signatures compliant with 21 CFR Part 11. While not exclusively a COA tool, its integrated LIMS and ERP connectivity streamline QC processes from lab to release.

BIOVIA, from Dassault Systèmes, is a comprehensive scientific informatics platform designed for R&D and manufacturing in life sciences and materials science. As a Certificate of Analysis (CoA) solution, it enables automated generation of CoAs through integration with ELNs, LIMS, and lab instruments, ensuring regulatory compliance and data integrity. It supports batch release processes with customizable templates and real-time analytics for quality assurance.