Top 10 Best Biorepository Software of 2026

FreezerPro by Azenta is a comprehensive biorepository management software that enables precise tracking, storage, and retrieval of biological samples across freezers, racks, and boxes. It offers advanced features like barcode/QR code scanning, full sample lineage tracking, audit trails for compliance (e.g., 21 CFR Part 11, GxP), and customizable workflows to optimize lab operations. The platform supports cloud and on-premise deployments, integrates with lab instruments, and provides powerful reporting and search capabilities for efficient sample management in research and biobanking environments.

Mosaic by Titian Software is a leading biorepository management platform that provides end-to-end tracking of biological samples from receipt through storage, processing, and distribution. It excels in automating workflows, inventory management, and sample requests for high-volume biobanks, pharmaceutical R&D labs, and research institutions. With strong compliance features like 21 CFR Part 11 support and integration with robotics and LIMS systems, it optimizes sample utilization and minimizes errors.

OpenSpecimen is an open-source biobanking platform designed to manage the full lifecycle of biospecimens in biorepositories, from collection and processing to storage, distribution, and research utilization. It provides tools for participant registration, specimen tracking, inventory management, and advanced querying for research cohorts. The software emphasizes compliance with regulations like HIPAA and GDPR, while supporting integrations with EHRs, LIS, and other clinical systems.

Freezerworks is a robust Laboratory Information Management System (LIMS) tailored for biorepositories, enabling precise tracking of biological samples across freezers, aliquots, and full pedigrees. It provides visual freezer mapping, automated workflows for check-in/out, and comprehensive reporting for compliance with standards like CAP, FDA 21 CFR Part 11, and ISO. Designed for biobanks and research labs, it supports unlimited users and customizable modules to streamline sample lifecycle management from receipt to disposal.

LabVantage is a comprehensive Laboratory Information Management System (LIMS) with specialized biorepository modules for managing biological sample collections, storage, and processing. It provides end-to-end tracking of specimens from intake, aliquoting, and storage to disposition, while ensuring compliance with regulations like 21 CFR Part 11 and ISO standards. The platform supports complex workflows, inventory management, and integrations with lab instruments and ELNs, making it suitable for research, clinical, and biobanking operations.

STARLIMS is a robust Laboratory Information Management System (LIMS) from Abbott Informatics, specifically adaptable for biorepository operations through its sample management modules. It handles end-to-end sample lifecycle processes, including accessioning, aliquoting, inventory tracking, storage optimization, and disposal, while ensuring compliance with regulations like 21 CFR Part 11, CAP, and ISO 20387. The platform supports workflow automation, instrument integrations, and advanced querying for biorepository-specific needs such as chain-of-custody and pedigree tracking.

SampleManager LIMS from Thermo Fisher Scientific is a robust enterprise-level Laboratory Information Management System tailored for biorepositories, enabling end-to-end sample lifecycle management from intake to archiving and disposal. It excels in tracking aliquots, managing storage locations across freezers and racks, and ensuring chain-of-custody compliance with regulations like 21 CFR Part 11 and ISO standards. The platform supports advanced querying, customizable workflows, and integration with lab instruments for automated data capture.

LabKey Server is a robust, web-based platform for managing scientific data in life sciences, with a dedicated Biorepository module for tracking biological samples from collection through storage and distribution. It supports inventory management, aliquot tracking, metadata annotation, quality control workflows, and integration with assays and studies. The system excels in handling complex relationships between samples and enables advanced querying, reporting, and compliance features for regulated environments.

CloudLIMS is a cloud-based Laboratory Information Management System (LIMS) specifically designed for biorepositories, offering comprehensive sample accessioning, tracking, inventory management, and chain-of-custody features. It supports biological sample lifecycle management, including aliquoting, derivatives, and disposal, with customizable workflows and regulatory compliance tools like 21 CFR Part 11 and ISO 17025. The platform enables real-time collaboration, instrument integrations, and reporting to streamline biorepository operations.

Matrix Gemini LIMS from Autoscribe Informatics is a highly configurable laboratory information management system tailored for biorepositories, enabling end-to-end sample lifecycle management from intake to disposal. It excels in tracking biological specimens, managing inventory across freezers and storage systems, and ensuring regulatory compliance with features like audit trails and chain-of-custody protocols. The software supports custom workflows and instrument integrations, making it adaptable for diverse biorepository operations.