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Healthcare Medicine

Top 10 Best Ambulatory Surgery Center Software of 2026

Explore top ambulatory surgery center software solutions to streamline operations. Compare features & pick the best for your facility today.

Sarah Mitchell

Sarah Mitchell

Feb 11, 2026

10 tools comparedExpert reviewed
Independent evaluation · Unbiased commentary · Updated regularly
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Ambulatory surgery centers (ASCs) rely on robust software to streamline operations, enhance patient care, and ensure regulatory compliance—making the right tool a strategic cornerstone. With a diverse range of solutions available, our curated list of top 10 providers offers a guide to selecting software tailored to meet the complex needs of modern ASCs.

Quick Overview

  1. 1#1: Surgical Information Systems (SIS) - Delivers comprehensive ASC software for scheduling, clinical documentation, inventory management, and revenue cycle optimization.
  2. 2#2: Amkai Solutions - Offers integrated EHR, practice management, and analytics tailored specifically for ambulatory surgery centers.
  3. 3#3: Adonis - Provides cloud-based ASC software with patient engagement, scheduling, billing, and compliance tools.
  4. 4#4: SourceMedical Ascend - Manages full ASC operations including HIS, EHR, supply chain, and business intelligence.
  5. 5#5: MDI Achieve - ASC-focused platform for perioperative workflow, anesthesia documentation, and quality reporting.
  6. 6#6: Health Care Software (HCS) - Supports ASCs with integrated scheduling, billing, EHR, and regulatory compliance features.
  7. 7#7: Clinicast - Streamlines ASC operations with real-time scheduling, case management, and financial reporting.
  8. 8#8: ForeSee Medical - Optimizes ASC revenue cycle management, claims processing, and patient collections.
  9. 9#9: eClinicalWorks - Provides scalable EHR and practice management solutions adaptable for ambulatory surgery centers.
  10. 10#10: NextGen Healthcare - Offers enterprise-grade ambulatory EHR with ASC-specific modules for clinical and financial workflows.

These tools were selected based on a combination of feature integration (scheduling, EHR, billing, compliance), user experience, and operational value, ensuring they deliver measurable efficiency and reliability for ASC workflows.

Comparison Table

Ambulatory surgery centers rely on specialized software to optimize operations, and choosing the right tool demands clear comparison of features. This table examines key options including Surgical Information Systems (SIS), Amkai Solutions, Adonis, SourceMedical Ascend, MDI Achieve, and more, offering insights into how each addresses clinical, administrative, and operational needs. Readers will gain a clear overview to identify software that aligns with their center’s specific requirements.

Delivers comprehensive ASC software for scheduling, clinical documentation, inventory management, and revenue cycle optimization.

Features
9.8/10
Ease
9.3/10
Value
9.2/10

Offers integrated EHR, practice management, and analytics tailored specifically for ambulatory surgery centers.

Features
9.5/10
Ease
8.5/10
Value
8.8/10
3Adonis logo8.6/10

Provides cloud-based ASC software with patient engagement, scheduling, billing, and compliance tools.

Features
9.1/10
Ease
8.0/10
Value
8.3/10

Manages full ASC operations including HIS, EHR, supply chain, and business intelligence.

Features
9.2/10
Ease
7.9/10
Value
8.3/10

ASC-focused platform for perioperative workflow, anesthesia documentation, and quality reporting.

Features
8.6/10
Ease
7.7/10
Value
8.0/10

Supports ASCs with integrated scheduling, billing, EHR, and regulatory compliance features.

Features
8.4/10
Ease
7.7/10
Value
8.0/10
7Clinicast logo7.2/10

Streamlines ASC operations with real-time scheduling, case management, and financial reporting.

Features
6.8/10
Ease
8.1/10
Value
7.5/10

Optimizes ASC revenue cycle management, claims processing, and patient collections.

Features
8.5/10
Ease
8.0/10
Value
7.9/10

Provides scalable EHR and practice management solutions adaptable for ambulatory surgery centers.

Features
7.8/10
Ease
6.5/10
Value
7.0/10

Offers enterprise-grade ambulatory EHR with ASC-specific modules for clinical and financial workflows.

Features
8.1/10
Ease
6.5/10
Value
7.0/10
1
Surgical Information Systems (SIS) logo

Surgical Information Systems (SIS)

specialized

Delivers comprehensive ASC software for scheduling, clinical documentation, inventory management, and revenue cycle optimization.

Overall Rating9.7/10
Features
9.8/10
Ease of Use
9.3/10
Value
9.2/10
Standout Feature

End-to-end perioperative data flow with automated charge capture and ASC benchmarking analytics

Surgical Information Systems (SIS), via SIS First, delivers a comprehensive perioperative software platform tailored for ambulatory surgery centers (ASCs). It integrates scheduling, patient registration, clinical documentation, inventory management, revenue cycle, and advanced analytics into a single, ASC-specific EHR solution. Designed to optimize workflows, ensure compliance, and maximize revenue capture, SIS empowers ASCs to operate efficiently from pre-op to post-op.

Pros

  • ASC-specific perioperative workflows with seamless integration across modules
  • Powerful revenue cycle management and denial prevention tools
  • Robust analytics dashboard for real-time insights and benchmarking

Cons

  • Custom pricing can be steep for smaller ASCs
  • Implementation may require significant upfront time and training
  • Customization options are somewhat limited compared to general EHRs

Best For

Mid-to-large ambulatory surgery centers needing a fully integrated, surgery-focused EHR and practice management system.

Pricing

Custom quote-based pricing, typically subscription per OR/user; starts around $500-1,000 per month per OR depending on modules and scale.

2
Amkai Solutions logo

Amkai Solutions

specialized

Offers integrated EHR, practice management, and analytics tailored specifically for ambulatory surgery centers.

Overall Rating9.2/10
Features
9.5/10
Ease of Use
8.5/10
Value
8.8/10
Standout Feature

Integrated anesthesia and clinical workflow module optimized specifically for ASC case management and regulatory compliance

Amkai Solutions offers Amkai Advanced, a cloud-based software platform purpose-built for ambulatory surgery centers (ASCs), integrating scheduling, patient registration, clinical documentation, billing, inventory management, and quality reporting into a single system. It streamlines ASC workflows from pre-op to post-op, ensuring compliance with regulations like PQRS and MACRA. Designed by ASC operators, it provides ASC-specific tools to optimize revenue cycle management and operational efficiency.

Pros

  • Comprehensive ASC-specific features including integrated EMR, anesthesia documentation, and QI analytics
  • Strong revenue cycle management with automated billing and claims scrubbing
  • Reliable cloud-based platform with excellent uptime and mobile access

Cons

  • Higher pricing suitable mainly for mid-to-large ASCs
  • Initial implementation and training can take several months
  • Limited third-party integrations compared to general EHR systems

Best For

Mid-sized to large multi-specialty ASCs needing an all-in-one, ASC-tailored solution for end-to-end operations.

Pricing

Custom quote-based pricing, typically $10,000+ monthly for mid-sized facilities depending on rooms, users, and modules; demo required.

3
Adonis logo

Adonis

specialized

Provides cloud-based ASC software with patient engagement, scheduling, billing, and compliance tools.

Overall Rating8.6/10
Features
9.1/10
Ease of Use
8.0/10
Value
8.3/10
Standout Feature

Advanced OR scheduling with block optimization and surgeon preference card management

Adonis is a specialized software platform designed for ambulatory surgery centers (ASCs), providing comprehensive management of surgical workflows including scheduling, electronic health records (EHR), billing, and inventory control. It streamlines operations from patient intake to post-op follow-up, with tools for compliance reporting and revenue cycle management. Tailored specifically for ASCs, Adonis helps optimize OR utilization and financial performance through integrated analytics.

Pros

  • Powerful ASC-specific scheduling and OR block management
  • Integrated EHR, billing, and compliance tools
  • Robust reporting and analytics for operational insights

Cons

  • Steep learning curve for initial setup and training
  • Pricing can be high for smaller facilities
  • Limited third-party integrations compared to larger EHR systems

Best For

Mid-sized ambulatory surgery centers seeking a dedicated, all-in-one platform for surgical operations and revenue optimization.

Pricing

Custom pricing based on facility size and modules; typically starts at $5,000/month for mid-sized ASCs with enterprise quotes required.

Visit Adonisadonissurgery.com
4
SourceMedical Ascend logo

SourceMedical Ascend

enterprise

Manages full ASC operations including HIS, EHR, supply chain, and business intelligence.

Overall Rating8.6/10
Features
9.2/10
Ease of Use
7.9/10
Value
8.3/10
Standout Feature

ASC-specific surgical case management with real-time inventory tracking and customizable procedure packs

SourceMedical Ascend is a comprehensive, ASC-specific software suite that integrates electronic health records (EHR), practice management, revenue cycle management, and surgical workflow tools tailored for ambulatory surgery centers. It supports end-to-end operations including patient scheduling, pre-op/anesthesia documentation, inventory management, and compliance reporting. Ascend emphasizes interoperability, analytics for performance optimization, and regulatory compliance to help ASCs streamline operations and maximize reimbursements.

Pros

  • Specialized ASC workflows for surgery scheduling, case management, and anesthesia tracking
  • Robust revenue cycle management with advanced billing and denial management tools
  • Strong analytics and reporting for operational insights and compliance

Cons

  • Steep learning curve due to extensive feature set
  • Custom pricing can be expensive for smaller ASCs
  • Interface feels somewhat dated compared to modern cloud-native competitors

Best For

Mid-to-large ambulatory surgery centers needing a fully integrated, enterprise-grade solution for complex surgical operations and revenue optimization.

Pricing

Custom enterprise pricing based on facility size and modules; typically subscription-based starting around $500/user/month, with implementation fees—contact for quote.

5
MDI Achieve logo

MDI Achieve

specialized

ASC-focused platform for perioperative workflow, anesthesia documentation, and quality reporting.

Overall Rating8.2/10
Features
8.6/10
Ease of Use
7.7/10
Value
8.0/10
Standout Feature

Advanced case costing and profitability analytics that track costs per procedure for optimized scheduling and reimbursements

MDI Achieve is a specialized software platform designed for ambulatory surgery centers (ASCs), providing integrated electronic health records (EHR), practice management, and revenue cycle management tools. It streamlines surgical workflows, including scheduling, pre-op/anesthesia documentation, intra-op charting, and post-op follow-up, while ensuring compliance with ASC regulations like MIPS and ASCQR. The system emphasizes financial performance through advanced billing, claims management, and analytics for optimizing case profitability.

Pros

  • Comprehensive ASC-specific modules for perioperative workflows and compliance
  • Strong revenue cycle management with high clean claim rates and analytics
  • Robust reporting and dashboards for operational and financial insights

Cons

  • User interface feels dated and less intuitive compared to modern cloud platforms
  • Steep learning curve for new users and customization requires vendor support
  • Limited native mobile app functionality and third-party integrations

Best For

Mid-sized ASCs seeking a proven, facility-focused solution with deep surgical and billing capabilities.

Pricing

Custom pricing per facility, typically $10,000-$50,000+ annually based on size, modules, and users; includes implementation fees.

Visit MDI Achievemdiachieve.com
6
Health Care Software (HCS) logo

Health Care Software (HCS)

specialized

Supports ASCs with integrated scheduling, billing, EHR, and regulatory compliance features.

Overall Rating8.1/10
Features
8.4/10
Ease of Use
7.7/10
Value
8.0/10
Standout Feature

Advanced block scheduling engine that optimizes OR utilization with surgeon-specific preferences and real-time availability

Health Care Software (HCS) offers an integrated EHR and practice management solution designed for ambulatory surgery centers, streamlining surgical scheduling, patient registration, clinical documentation, and billing processes. It supports ASC-specific workflows like block scheduling, anesthesia records, and inventory management for supplies and implants. The platform emphasizes compliance with HIPAA and MACRA while providing robust reporting for operational efficiency.

Pros

  • Strong revenue cycle management with automated claims scrubbing
  • Customizable templates for surgical workflows and documentation
  • Reliable customer support with dedicated ASC specialists

Cons

  • Dated user interface that may require training
  • Limited native mobile app functionality
  • Higher implementation costs for smaller centers

Best For

Mid-sized ambulatory surgery centers seeking a comprehensive, billing-focused EHR/PM system with solid customization options.

Pricing

Quote-based pricing starting at approximately $300-$500 per user/month, depending on modules and practice size; includes implementation fees.

7
Clinicast logo

Clinicast

specialized

Streamlines ASC operations with real-time scheduling, case management, and financial reporting.

Overall Rating7.2/10
Features
6.8/10
Ease of Use
8.1/10
Value
7.5/10
Standout Feature

Seamless block time scheduling with automated surgeon preference capture

Clinicast is a cloud-based practice management software tailored for ambulatory surgery centers (ASCs) and clinics, offering tools for appointment scheduling, patient records, billing, and basic inventory tracking. It supports surgical workflows with features like OR scheduling and surgeon preferences, while ensuring HIPAA compliance for secure data handling. The platform emphasizes ease of use for smaller ASCs, with customizable dashboards and reporting capabilities to streamline daily operations.

Pros

  • Intuitive interface with quick setup for non-technical staff
  • Affordable pricing suitable for small ASCs
  • Reliable HIPAA-compliant patient portal and mobile access

Cons

  • Limited advanced OR block scheduling compared to specialized ASC tools
  • Fewer integrations with major EHR systems like Epic or Cerner
  • Basic reporting lacks deep analytics for large-scale operations

Best For

Small to mid-sized ambulatory surgery centers seeking a cost-effective, user-friendly solution without complex enterprise needs.

Pricing

Starts at $149 per user/month for core features, with custom enterprise plans available upon request.

Visit Clinicastclinicast.com
8
ForeSee Medical logo

ForeSee Medical

specialized

Optimizes ASC revenue cycle management, claims processing, and patient collections.

Overall Rating8.2/10
Features
8.5/10
Ease of Use
8.0/10
Value
7.9/10
Standout Feature

Predictive revenue forecasting that anticipates cash flow and identifies potential claim issues before submission

ForeSee Medical offers a cloud-based software platform tailored for ambulatory surgery centers (ASCs), integrating scheduling, electronic health records (EHR), patient registration, clinical documentation, inventory management, and revenue cycle management into a single system. It emphasizes HIPAA-compliant workflows, real-time analytics, and interoperability with major EHRs and billing systems to streamline ASC operations. The solution helps facilities improve efficiency, reduce claim denials, and enhance financial performance through predictive revenue insights.

Pros

  • Comprehensive ASC-specific modules covering full workflow from scheduling to billing
  • Strong revenue cycle management with denial prevention tools
  • Real-time dashboards and mobile accessibility for on-the-go management

Cons

  • Limited advanced AI-driven features compared to top competitors
  • Customization options can be restrictive for larger facilities
  • Pricing requires custom quotes, lacking transparency

Best For

Small to mid-sized ASCs seeking an integrated, compliance-focused platform without needing extensive custom development.

Pricing

Custom pricing via quote; modular subscriptions typically range from $300-$800 per user/month depending on facility size and features.

Visit ForeSee Medicalforeseemed.com
9
eClinicalWorks logo

eClinicalWorks

enterprise

Provides scalable EHR and practice management solutions adaptable for ambulatory surgery centers.

Overall Rating7.3/10
Features
7.8/10
Ease of Use
6.5/10
Value
7.0/10
Standout Feature

AI-powered clinical documentation and ambient listening via Sunoh.ai for faster perioperative charting

eClinicalWorks is a comprehensive cloud-based EHR and practice management platform tailored for ambulatory care, including Ambulatory Surgery Centers (ASCs). It streamlines surgical workflows with features like perioperative documentation, OR scheduling, inventory management, and compliance tools such as ASCQR reporting. The system also integrates telehealth, patient engagement via the Healow app, and revenue cycle management to support efficient operations in outpatient surgical settings.

Pros

  • Robust interoperability with HIEs and labs for seamless data exchange
  • Specialty-specific templates and surgical workflow customization
  • Integrated RCM and analytics for improved billing efficiency

Cons

  • Steep learning curve due to complex interface
  • Inconsistent customer support experiences
  • Custom pricing can be opaque and higher for smaller ASCs

Best For

Mid-sized Ambulatory Surgery Centers needing a scalable, all-in-one EHR with strong population health and telehealth integration.

Pricing

Custom subscription pricing typically $400-$700 per provider/month plus implementation fees; volume discounts available.

Visit eClinicalWorkseclinicalworks.com
10
NextGen Healthcare logo

NextGen Healthcare

enterprise

Offers enterprise-grade ambulatory EHR with ASC-specific modules for clinical and financial workflows.

Overall Rating7.4/10
Features
8.1/10
Ease of Use
6.5/10
Value
7.0/10
Standout Feature

Advanced revenue cycle management with AI-driven claims optimization

NextGen Healthcare offers a comprehensive cloud-based EHR and practice management platform tailored for ambulatory practices, including ambulatory surgery centers (ASCs). It streamlines workflows with features like patient scheduling, surgical documentation, billing, revenue cycle management, and interoperability via standards like FHIR. While versatile for outpatient settings, it adapts general ambulatory tools to ASC needs such as OR scheduling and compliance reporting.

Pros

  • Strong interoperability and FHIR support for seamless data exchange
  • Robust revenue cycle management with analytics for ASC billing
  • Customizable templates for surgical documentation and workflows

Cons

  • Steep learning curve due to complex interface
  • Less specialized for ASC-specific needs like advanced OR block scheduling compared to dedicated tools
  • Higher implementation costs and potential support delays

Best For

Mid-sized ambulatory surgery centers seeking an integrated EHR/PM solution with enterprise-level analytics and scalability.

Pricing

Subscription-based, typically $400-$700 per provider/month plus implementation fees; custom enterprise quotes required.

Conclusion

The reviewed tools offer tailored solutions for ambulatory surgery centers, with Surgical Information Systems (SIS) leading as the top choice, excelling in comprehensive scheduling, clinical documentation, and revenue cycle management. Amkai Solutions and Adonis follow closely, providing integrated features that cater to diverse operational needs, ensuring even specialized workflows are effectively supported. Together, they highlight the innovation driving the industry forward.

Surgical Information Systems (SIS) logo
Our Top Pick
Surgical Information Systems (SIS)

Explore Surgical Information Systems (SIS) to unlock its full potential for optimizing your ASC's scheduling, documentation, and revenue cycle—take the next step toward streamlined operations today.