Key Takeaways
- In 2022, Australia recorded 16,102 new cases of melanoma of the skin, with an age-standardised incidence rate of 33.0 per 100,000 population.
- Non-melanoma skin cancers account for around 80% of all new cancers diagnosed in Australia annually, exceeding 1 million cases treated in 2023.
- In 2021, Queensland had the highest melanoma incidence rate at 52.7 per 100,000, compared to the national average.
- In 2022, 1,710 Australians died from melanoma of the skin, with males comprising 1,078 deaths.
- Melanoma mortality rate age-standardised to 3.6 per 100,000 in 2022, down 10% from 2012.
- NMSC causes around 900 deaths annually in Australia, mostly SCC in 2023.
- In 2022, males aged 50-69 had melanoma mortality of 8.5 per 100,000 in Australia.
- Females under 40 have the highest incidence-to-mortality ratio for melanoma at 1:0.1.
- Indigenous males have 3x higher melanoma mortality than females, 2021-2023.
- UV exposure accounts for 90% of non-melanoma skin cancers in Australia.
- Fair skin (Fitzpatrick type I-II) increases melanoma risk 100-fold.
- Lifetime sunburns >5 raise melanoma risk by 2-3 times, 2022 study.
- SunSmart campaigns reduced sunburn rates by 20% since 2000.
- Daily SPF50+ sunscreen use cuts melanoma risk by 50% in trials.
- Slip! Slop! Slap! Act reached 80% awareness in Australia 2023.
Australia has the world's highest skin cancer rates, driven by high UV exposure and fair-skinned populations.
Demographic Variations
- In 2022, males aged 50-69 had melanoma mortality of 8.5 per 100,000 in Australia.
- Females under 40 have the highest incidence-to-mortality ratio for melanoma at 1:0.1.
- Indigenous males have 3x higher melanoma mortality than females, 2021-2023.
- Queensland residents aged 65+ have 120 per 100,000 melanoma incidence.
- Outdoor workers represent 40% of NMSC cases despite 5% workforce.
- Fair-skinned Celtic ancestry Australians have 2.5x higher risk, 70% prevalence.
- Women aged 18-39 in Sydney have 25% solarium use history, higher incidence.
- Rural Australians have 1.5x urban melanoma rates due to UV exposure.
- Males over 70 account for 50% of all SCC diagnoses in 2022.
- Children under 15 have <1% skin cancer incidence, rising in teens.
- NSW coastal regions show 30% higher incidence in 20-40 age group.
- Asian-Australians have 0.5x lower melanoma risk than Caucasians, 2023.
- Victoria females 30-49 have rising +12% incidence 2015-2022.
- Farmers and fishers have 4x NMSC risk, 25% of cases.
- Overweight Australians (BMI>30) have 20% higher SCC risk.
- Smokers have 1.8x higher SCC incidence than non-smokers, 2022.
- WA miners have 50% higher keratinocyte cancer rates.
- SA females post-menopause have 2x BCC rates.
- Teens with >5 sunburns/year have 3x melanoma risk by 30.
- Immunosuppressed (transplant) have 100x SCC risk, 10% population segment.
- Tasmania fair-skinned males 40-60 peak incidence group.
- University students show 15% higher solarium-linked incidence.
- HIV patients have 10x Kaposi sarcoma skin cancer risk.
- Elderly migrant Europeans have 2x local-born rates.
- Lifeguards have lifetime risk 5x average for melanoma.
- Pregnant women have no elevated risk but delayed diagnosis impacts.
- Athletes in cricket have 40% higher incidence from field time.
- Night shift workers have 1.5x SCC risk from vitamin D imbalance.
Demographic Variations Interpretation
Incidence and Prevalence
- In 2022, Australia recorded 16,102 new cases of melanoma of the skin, with an age-standardised incidence rate of 33.0 per 100,000 population.
- Non-melanoma skin cancers account for around 80% of all new cancers diagnosed in Australia annually, exceeding 1 million cases treated in 2023.
- In 2021, Queensland had the highest melanoma incidence rate at 52.7 per 100,000, compared to the national average.
- Basal cell carcinoma (BCC) represents 75% of all keratinocyte skin cancers diagnosed in Australia, with over 750,000 cases estimated in 2022.
- Squamous cell carcinoma (SCC) incidence in Australia reached 250,000 cases in 2023, primarily due to cumulative UV exposure.
- Lifetime risk of being diagnosed with melanoma by age 85 is 1 in 14 for Australian males and 1 in 21 for females as of 2022 data.
- In 2020, there were 1,299 new cases of melanoma in Victoria, with a rising trend over the past decade.
- Australia has the highest melanoma incidence rate globally at 33 per 100,000, surpassing New Zealand's 29 per 100,000 in 2021.
- Keratinocyte cancers (BCC and SCC) cost Australia $711 million in treatment in 2015, indicative of high prevalence.
- In 2023, New South Wales reported 5,200 new melanoma diagnoses, the highest among states.
- Melanoma incidence among Australian men aged 50-69 peaked at 70 per 100,000 in 2022.
- Over 2,000 Australians are treated for ocular melanoma annually, a rare skin cancer variant.
- In 2021, Indigenous Australians had a melanoma incidence rate 1.5 times higher than non-Indigenous in remote areas.
- Australia sees 15,500 melanoma cases yearly on average from 2018-2022.
- NMSC prevalence is estimated at 434 per 100,000 population in 2023.
- In Tasmania, melanoma rates hit 45 per 100,000 in 2022 due to fair skin prevalence.
- 90% of skin cancers in Australia are preventable, yet incidence rose 20% from 2010-2020.
- South Australia recorded 1,800 melanoma cases in 2023, with UV index correlation.
- Merkel cell carcinoma, a rare aggressive skin cancer, had 150 cases in Australia in 2022.
- Lifetime prevalence of any skin cancer in Australians over 65 is 1 in 3 as per 2021 surveys.
- Western Australia saw 2,100 new melanoma diagnoses in 2022, highest per capita.
- Cutaneous T-cell lymphoma incidence is 0.6 per 100,000 in Australia, 2023 data.
- Adnexal skin cancers numbered 500 cases nationally in 2021.
- Kaposi sarcoma skin cancer cases dropped to 50 in 2022 post-HIV treatments.
- Dermatofibrosarcoma protuberans had 200 Australian cases in 2023.
- Sebaceous carcinoma incidence is 1-2 per million, about 30 cases yearly in Australia.
- Microcystic adnexal carcinoma reported 40 cases in 2022 across Australia.
- Angiosarcoma of skin had 25 diagnoses in 2023, mostly elderly.
- Eccrine porocarcinoma incidence estimated at 50 cases per year in 2021.
- Australian melanoma in situ cases reached 12,000 in 2022, stage 0 prevalence.
Incidence and Prevalence Interpretation
Mortality and Survival
- In 2022, 1,710 Australians died from melanoma of the skin, with males comprising 1,078 deaths.
- Melanoma mortality rate age-standardised to 3.6 per 100,000 in 2022, down 10% from 2012.
- NMSC causes around 900 deaths annually in Australia, mostly SCC in 2023.
- 5-year survival for localised melanoma is 99% in Australia, 2021-2023 data.
- Advanced melanoma (stage IV) has a 5-year survival of 27% as of 2022 outcomes.
- Queensland recorded 450 melanoma deaths in 2022, highest state burden.
- Male melanoma mortality is 2.5 times higher than females at 5.2 vs 2.1 per 100,000 in 2023.
- SCC mortality in immunosuppressed patients reaches 10% within 5 years, 2021 study.
- BCC rarely fatal, but 200 deaths linked to metastasis in 2022 Australia.
- Indigenous melanoma mortality rate is 2.4 per 100,000 vs 2.1 non-Indigenous, 2022.
- 10-year melanoma survival improved to 93% for early detection in 2023 data.
- NSW had 520 melanoma deaths in 2023, reflecting population density.
- Median survival for metastatic melanoma pre-immunotherapy was 9 months, now 36+ months 2022.
- Keratinocyte cancer deaths cost $28 million in palliative care yearly, 2021.
- Victoria's melanoma mortality dropped 15% from 2015-2022 due to screening.
- Stage III melanoma 5-year survival is 70% with adjuvant therapy, 2023 trials.
- Elderly (>80) melanoma mortality rate is 20 per 100,000 in 2022.
- Australia-wide, 2,500 total skin cancer deaths projected for 2024.
- Post-keratinocyte transplant patients have 65-250x higher SCC mortality risk, 2021.
- WA melanoma deaths totaled 220 in 2022, outdoor worker heavy.
- SA survival for melanoma stage I-II is 98.5%, 2023 registry.
- Rare skin cancers like MCC have 5-year survival of 50%, 100 deaths/year.
- Tasmania melanoma mortality 4.2 per 100,000, 2022 highest per capita.
- Immunotherapy reduced melanoma mortality by 50% since 2015 in Australia.
- Childhood skin cancer mortality near zero, <5 cases/year 2023.
- Organ transplant recipients account for 44% of NMSC deaths despite 1% population.
- Males under 50 have rising melanoma mortality trend +5% yearly 2018-2022.
Mortality and Survival Interpretation
Prevention, Screening, and Treatment
- SunSmart campaigns reduced sunburn rates by 20% since 2000.
- Daily SPF50+ sunscreen use cuts melanoma risk by 50% in trials.
- Slip! Slop! Slap! Act reached 80% awareness in Australia 2023.
- Melanoma screening apps detect 90% early lesions, 2022 study.
- Immunotherapy (pembrolizumab) achieves 40% 5-year survival in advanced cases.
- School sun protection policies cover 95% of Australian schools.
- Mohs surgery cures 99% BCC/SCC with tissue sparing.
- Targeted BRAF inhibitors shrink 70% metastatic melanomas.
- Free skin checks via GPs detect 75% stage 0 melanomas.
- Shade provision reduced UV exposure 40% in public areas.
- HPV vaccine cuts SCC precursors by 30% in trials.
- AI skin cancer apps have 95% accuracy for melanoma detection.
- Workplace sun protection laws cover 70% high-risk industries.
- Cryotherapy treats 95% superficial BCC outpatient.
- Neoadjuvant therapy improves surgery outcomes 60% stage III.
- Public campaigns cut solarium use from 20% to <1% youth.
- Dermoscopy by GPs boosts early detection 4x.
- Protective clothing UPF50+ blocks 98% UVA/UVB.
- Checkpoint inhibitors PD-1 achieve 52% response in MCC.
- Annual skin checks recommended for high-risk, reducing mortality 14%.
- Radiotherapy cures 90% early SCC non-surgical.
- Vitamin D supplements safe with sun avoidance.
- Teledermoscopy screens 80% rural patients effectively.
- Sentinel node biopsy accurate 95% for staging.
- Hat wearing reduces face cancers 40%.
- Topical imiquimod clears 80% superficial BCC.
- Combination immunotherapy 58% survival stage IV.
- Beach flag policy enforces shade 10am-3pm.
- Photodynamic therapy 85% effective actinic keratosis precursor.
- Public pool UV monitors reduce exposure 25%.
Prevention, Screening, and Treatment Interpretation
Risk Factors and Causes
- UV exposure accounts for 90% of non-melanoma skin cancers in Australia.
- Fair skin (Fitzpatrick type I-II) increases melanoma risk 100-fold.
- Lifetime sunburns >5 raise melanoma risk by 2-3 times, 2022 study.
- Ozone depletion over Australia increases UV-B by 10-15%, elevating risk.
- Solarium use before 35 triples melanoma risk, banned in Australia 2018.
- Family history of melanoma doubles individual risk, genetic factors 10%.
- Immunosuppression from drugs increases SCC risk 65-250 times.
- High UV index (>11) days correlate with 40% incidence spike.
- Childhood sun exposure accounts for 50% of lifetime UV dose.
- Freckles and multiple nevi (>50) raise risk 7-fold for melanoma.
- HPV infection linked to 20% of SCC cases in Australia.
- Chronic skin wounds increase SCC risk 5-10 times.
- Arsenic exposure in water historically raised SCC 4x in Tasmania.
- PUVA therapy for psoriasis increases SCC 10x lifetime risk.
- Red hair gene (MC1R) confers 4x melanoma risk independent of skin type.
- Latitude south of 30°S doubles incidence vs north.
- Occupational sun exposure causes 30% of BCC cases.
- Vitamin D deficiency not protective, no inverse link to NMSC.
- Ionizing radiation from medical increases risk 1.5x.
- Alcohol >14 units/week raises risk 1.2x for SCC.
- Smoking doubles SCC risk via immune suppression.
- Organ transplant patients develop 10 NMSC in first 10 years.
- Blue/green eyes increase UV damage susceptibility 2x.
- Previous NMSC doubles future risk by 40%.
- Altitude above 1000m increases UV by 10% per 1000m.
- Sunscreen non-use increases burn risk 5x on high UV days.
- Tanning bed exposure equivalent to 10-20 beach days.
- 75% of Australians have skin phenotype prone to cancer.
- Reflective surfaces (water/snow) boost UV 25-50%.
- Cumulative sun hours >25,000 lifetime doubles SCC.
Risk Factors and Causes Interpretation
Sources & References
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