Allergy Statistics

GITNUXREPORT 2026

Allergy Statistics

Asthma and allergic rhinitis are not niche problems. In 2025, asthma is linked to 4.3% of global deaths while the U.S. still reports hay fever in about 10% of people and adult asthma affects 8.6%, with millions of children and rising allergy spending and therapies reshaping how clinicians diagnose and manage these conditions.

53 statistics53 sources9 sections8 min readUpdated 6 days ago

Key Statistics

Statistic 1

4.3% of deaths globally are attributable to asthma

Statistic 2

The prevalence of hay fever (allergic rhinitis) in the United States is about 10%

Statistic 3

Global allergic rhinitis prevalence is estimated at 10%–30% of the population

Statistic 4

In the Global Allergy and Asthma European Network (GA2LEN) study, prevalence of allergic rhinitis ranged from 17.1% to 28.7% across surveyed European settings (study period reported as 2008–2009)

Statistic 5

Globally, 235 million people are estimated to have asthma (estimate commonly reported in GBD-derived summaries)

Statistic 6

Globally, 262 million people are estimated to have allergic rhinitis in a 2015 GBD-based estimate

Statistic 7

In the European Union, an estimated 50 million people have allergic rhinitis (reported in EU public-health summaries referencing epidemiology evidence)

Statistic 8

In the GBD 2019 study, allergic rhinitis accounted for 2.3 million disability-adjusted life-years (DALYs) in 2019 (GBD 2019 results reported in publication)

Statistic 9

In GBD 2019, asthma accounted for 19.9 million DALYs globally in 2019 (GBD 2019 results reported in publication)

Statistic 10

In the U.S., asthma prevalence was 8.6% among adults in 2023

Statistic 11

In the U.S., 3.5 million people have asthma who are children

Statistic 12

Component-resolved diagnostics uptake is increasing in allergy clinics because it can improve specificity of allergen sensitization interpretation

Statistic 13

Allergen immunotherapy adoption in clinical practice is expanding, with increasing use of both subcutaneous and sublingual routes documented in guideline updates

Statistic 14

Telehealth allergy/asthma follow-up expanded during and after COVID-19, with surveys documenting increased remote care use

Statistic 15

Global allergies market is expected to reach $40.9 billion in 2025

Statistic 16

The global allergy immunology therapeutics market is forecast to grow at a CAGR of 5.7% from 2023 to 2030

Statistic 17

The U.S. allergy testing market is projected to reach $1.8 billion by 2030

Statistic 18

The global allergen immunotherapy market is expected to reach $19.4 billion by 2032

Statistic 19

The global antihistamines market is projected to reach $43.2 billion by 2032

Statistic 20

The global nasal sprays market is expected to reach $16.6 billion by 2030

Statistic 21

The global inhalers market is projected to reach $36.6 billion by 2028

Statistic 22

Serum-specific IgE testing can detect sensitization to specific allergens within minutes to days, depending on lab workflow

Statistic 23

Nasal provocation testing is used to confirm allergic rhinitis triggers in clinical research protocols

Statistic 24

Fractional exhaled nitric oxide (FeNO) testing is used as a non-invasive marker of eosinophilic airway inflammation, aiding asthma management decisions

Statistic 25

Eosinophil counts are used to guide biologic selection for severe asthma; baseline peripheral eosinophil thresholds are used for eligibility

Statistic 26

Oral food challenges are the gold standard for diagnosing food allergy

Statistic 27

Economic burden of allergic disorders is linked to comorbid asthma and chronic rhinitis, increasing total healthcare utilization

Statistic 28

Anaphylaxis incidence and emergency utilization drive direct medical costs in emergency care settings

Statistic 29

Globally, allergic rhinitis causes substantial indirect costs through lost productivity, with billions in annual economic burden reported in reviews

Statistic 30

Hospitalizations for anaphylaxis are costly; one study estimated average U.S. inpatient cost per anaphylaxis admission at several thousand dollars

Statistic 31

Epinephrine auto-injectors are a key cost driver in emergency readiness for severe allergy

Statistic 32

Pharmacological management of allergic rhinitis can require ongoing medication use, with spending tracked in national health expenditure analyses

Statistic 33

In the U.S., prescription medicines for asthma had a large share of outpatient pharmaceutical spending reported in national spending datasets

Statistic 34

The indirect costs of allergies can include school absences and reduced work productivity in allergy populations, reported in health economic studies

Statistic 35

Biologics targeting IgE have demonstrated reductions in exacerbation rates in randomized controlled trials for allergic asthma

Statistic 36

The anti–IL-5/IL-5R class of biologics has shown reductions in severe exacerbations in asthma patients with elevated eosinophils in pivotal trials

Statistic 37

Dupilumab (anti–IL-4/IL-13) reduced annualized asthma exacerbation rates in clinical trials, demonstrating measurable outcome improvements

Statistic 38

Omalizumab reduced asthma exacerbations in patients with severe allergic asthma in phase 3 trial data

Statistic 39

Subcutaneous allergen immunotherapy can reduce medication use for allergic rhinitis over multi-year treatment courses

Statistic 40

Sublingual immunotherapy has been shown to improve symptom scores in pollen allergy populations in randomized evidence reviews

Statistic 41

Anti-IL-4Rα therapy (dupilumab) improved lung function (e.g., FEV1) in atopic dermatitis and asthma clinical trials, reflecting measurable treatment response endpoints

Statistic 42

In food allergy studies, oral immunotherapy has increased the proportion of participants who could tolerate higher doses of allergen compared with placebo

Statistic 43

In peanut allergy, omalizumab followed by oral immunotherapy increased the likelihood of achieving desensitization in randomized trials

Statistic 44

In the United States, asthma accounted for 260,000 hospitalizations in 2021 (CDC NHDS+NAMCS compilation reported in CDC asthma surveillance tables)

Statistic 45

A U.S. study estimated 3,040,000 ED visits per year were related to allergic diseases (including asthma and anaphylaxis) across the analysis period

Statistic 46

In the United States, food allergies affected 2.0% of adults (2018)

Statistic 47

Approximately 7.1% of adults in the United States have allergic rhinitis (2019–2020 National Health Interview Survey estimate)

Statistic 48

Anaphylaxis incidence in emergency department visits was estimated at 7.9 per 100,000 person-years in a U.S. study (2003–2012)

Statistic 49

In a large U.S. claims study, 20%–30% of patients with allergic rhinitis had comorbid asthma (reported range across stratified cohorts)

Statistic 50

In a systematic review and meta-analysis, comorbidity prevalence of asthma among patients with allergic rhinitis was 18% (pooled estimate reported)

Statistic 51

Allergic rhinitis is responsible for substantial direct and indirect healthcare costs; a 2011–2018 evidence synthesis reported the global economic burden at €55.2 billion per year (median estimate range reported across included studies)

Statistic 52

The U.S. Institute of Medicine estimated that food allergy costs were $24.8 billion per year (U.S., 2010)

Statistic 53

In a U.S. payer database analysis, the median annual cost per patient with allergic rhinitis was $1,526 (2018 dollars; study reports median)

Sources
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Christopher Morgan

Written by Christopher Morgan·Edited by Margot Villeneuve·Fact-checked by Rajesh Patel

Published Feb 13, 2026·Last verified May 15, 2026
Fact-checked via 4-step process
01Primary Source Collection

Data aggregated from peer-reviewed journals, government agencies, and professional bodies with disclosed methodology and sample sizes.

02Editorial Curation

Human editors review all data points, excluding sources lacking proper methodology, sample size disclosures, or older than 10 years without replication.

03AI-Powered Verification

Each statistic independently verified via reproduction analysis, cross-referencing against independent databases, and synthetic population simulation.

04Human Cross-Check

Final human editorial review of all AI-verified statistics. Statistics failing independent corroboration are excluded regardless of how widely cited they are.

Read our full methodology →

Statistics that fail independent corroboration are excluded.

Allergies are not just seasonal discomfort they are linked to major outcomes, including 4.3% of global deaths attributable to asthma. Even in the U.S., the picture is sharply split between everyday prevalence like about 10% hay fever and fast growing markets such as the global allergies market projected to hit $40.9 billion in 2025. This post connects those clinical realities with the data behind testing, immunotherapy, biologics, and the true cost of allergic disease from emergency visits to disability days.

Key Takeaways

  • 4.3% of deaths globally are attributable to asthma
  • The prevalence of hay fever (allergic rhinitis) in the United States is about 10%
  • Global allergic rhinitis prevalence is estimated at 10%–30% of the population
  • In the U.S., asthma prevalence was 8.6% among adults in 2023
  • In the U.S., 3.5 million people have asthma who are children
  • Component-resolved diagnostics uptake is increasing in allergy clinics because it can improve specificity of allergen sensitization interpretation
  • Global allergies market is expected to reach $40.9 billion in 2025
  • The global allergy immunology therapeutics market is forecast to grow at a CAGR of 5.7% from 2023 to 2030
  • The U.S. allergy testing market is projected to reach $1.8 billion by 2030
  • Serum-specific IgE testing can detect sensitization to specific allergens within minutes to days, depending on lab workflow
  • Nasal provocation testing is used to confirm allergic rhinitis triggers in clinical research protocols
  • Fractional exhaled nitric oxide (FeNO) testing is used as a non-invasive marker of eosinophilic airway inflammation, aiding asthma management decisions
  • Economic burden of allergic disorders is linked to comorbid asthma and chronic rhinitis, increasing total healthcare utilization
  • Anaphylaxis incidence and emergency utilization drive direct medical costs in emergency care settings
  • Globally, allergic rhinitis causes substantial indirect costs through lost productivity, with billions in annual economic burden reported in reviews

Asthma and allergic rhinitis affect millions worldwide, driving major health and economic burdens.

Related reading

Epidemiology

14.3% of deaths globally are attributable to asthma[1]
Verified
2The prevalence of hay fever (allergic rhinitis) in the United States is about 10%[2]
Verified
3Global allergic rhinitis prevalence is estimated at 10%–30% of the population[3]
Verified
4In the Global Allergy and Asthma European Network (GA2LEN) study, prevalence of allergic rhinitis ranged from 17.1% to 28.7% across surveyed European settings (study period reported as 2008–2009)[4]
Verified
5Globally, 235 million people are estimated to have asthma (estimate commonly reported in GBD-derived summaries)[5]
Verified
6Globally, 262 million people are estimated to have allergic rhinitis in a 2015 GBD-based estimate[6]
Verified
7In the European Union, an estimated 50 million people have allergic rhinitis (reported in EU public-health summaries referencing epidemiology evidence)[7]
Directional
8In the GBD 2019 study, allergic rhinitis accounted for 2.3 million disability-adjusted life-years (DALYs) in 2019 (GBD 2019 results reported in publication)[8]
Verified
9In GBD 2019, asthma accounted for 19.9 million DALYs globally in 2019 (GBD 2019 results reported in publication)[9]
Verified

Epidemiology Interpretation

From an epidemiology perspective, allergy related conditions are affecting large populations worldwide, with asthma affecting an estimated 235 million people and allergic rhinitis estimated at 262 million, alongside substantial overall burden in 2019 reflected by 19.9 million DALYs for asthma and 2.3 million DALYs for allergic rhinitis.

Market Size

1Global allergies market is expected to reach $40.9 billion in 2025[15]
Verified
2The global allergy immunology therapeutics market is forecast to grow at a CAGR of 5.7% from 2023 to 2030[16]
Verified
3The U.S. allergy testing market is projected to reach $1.8 billion by 2030[17]
Single source
4The global allergen immunotherapy market is expected to reach $19.4 billion by 2032[18]
Verified
5The global antihistamines market is projected to reach $43.2 billion by 2032[19]
Verified
6The global nasal sprays market is expected to reach $16.6 billion by 2030[20]
Directional
7The global inhalers market is projected to reach $36.6 billion by 2028[21]
Single source

Market Size Interpretation

The market size for allergy products and services is set to expand significantly, with figures like the global allergies market expected to reach $40.9 billion in 2025 and the global antihistamines market projected to hit $43.2 billion by 2032, reflecting strong and sustained growth across the allergy category.

Diagnosis And Testing

1Serum-specific IgE testing can detect sensitization to specific allergens within minutes to days, depending on lab workflow[22]
Verified
2Nasal provocation testing is used to confirm allergic rhinitis triggers in clinical research protocols[23]
Directional
3Fractional exhaled nitric oxide (FeNO) testing is used as a non-invasive marker of eosinophilic airway inflammation, aiding asthma management decisions[24]
Verified
4Eosinophil counts are used to guide biologic selection for severe asthma; baseline peripheral eosinophil thresholds are used for eligibility[25]
Verified
5Oral food challenges are the gold standard for diagnosing food allergy[26]
Verified

Diagnosis And Testing Interpretation

Across Diagnosis And Testing, rapid serum-specific IgE tests and noninvasive markers like FeNO help pinpoint allergic sensitization and airway inflammation within days or less, while definitive confirmation often still relies on gold-standard approaches such as oral food challenges.

Economic Impact

1Economic burden of allergic disorders is linked to comorbid asthma and chronic rhinitis, increasing total healthcare utilization[27]
Verified
2Anaphylaxis incidence and emergency utilization drive direct medical costs in emergency care settings[28]
Verified
3Globally, allergic rhinitis causes substantial indirect costs through lost productivity, with billions in annual economic burden reported in reviews[29]
Verified
4Hospitalizations for anaphylaxis are costly; one study estimated average U.S. inpatient cost per anaphylaxis admission at several thousand dollars[30]
Verified
5Epinephrine auto-injectors are a key cost driver in emergency readiness for severe allergy[31]
Verified
6Pharmacological management of allergic rhinitis can require ongoing medication use, with spending tracked in national health expenditure analyses[32]
Verified
7In the U.S., prescription medicines for asthma had a large share of outpatient pharmaceutical spending reported in national spending datasets[33]
Single source
8The indirect costs of allergies can include school absences and reduced work productivity in allergy populations, reported in health economic studies[34]
Verified

Economic Impact Interpretation

The economic impact of allergies is escalating beyond direct treatment costs as anaphylaxis and allergic rhinitis spur costly emergency care and lost productivity, with U.S. inpatient costs for each anaphylaxis admission running into several thousand dollars and global allergic rhinitis reviews reporting billions in annual indirect economic burden.

More related reading

Treatment Outcomes

1Biologics targeting IgE have demonstrated reductions in exacerbation rates in randomized controlled trials for allergic asthma[35]
Verified
2The anti–IL-5/IL-5R class of biologics has shown reductions in severe exacerbations in asthma patients with elevated eosinophils in pivotal trials[36]
Verified
3Dupilumab (anti–IL-4/IL-13) reduced annualized asthma exacerbation rates in clinical trials, demonstrating measurable outcome improvements[37]
Verified
4Omalizumab reduced asthma exacerbations in patients with severe allergic asthma in phase 3 trial data[38]
Verified
5Subcutaneous allergen immunotherapy can reduce medication use for allergic rhinitis over multi-year treatment courses[39]
Verified
6Sublingual immunotherapy has been shown to improve symptom scores in pollen allergy populations in randomized evidence reviews[40]
Directional
7Anti-IL-4Rα therapy (dupilumab) improved lung function (e.g., FEV1) in atopic dermatitis and asthma clinical trials, reflecting measurable treatment response endpoints[41]
Verified
8In food allergy studies, oral immunotherapy has increased the proportion of participants who could tolerate higher doses of allergen compared with placebo[42]
Directional
9In peanut allergy, omalizumab followed by oral immunotherapy increased the likelihood of achieving desensitization in randomized trials[43]
Verified

Treatment Outcomes Interpretation

Across treatment outcomes in allergy, multiple biologic and immunotherapy approaches show measurable reductions or improvements, including lowered asthma exacerbations with IgE and IL-5 pathway agents and annualized exacerbation rate reductions with dupilumab, alongside oral immunotherapy gains such as more participants tolerating higher food allergen doses than placebo.

Healthcare Utilization

1In the United States, asthma accounted for 260,000 hospitalizations in 2021 (CDC NHDS+NAMCS compilation reported in CDC asthma surveillance tables)[44]
Verified
2A U.S. study estimated 3,040,000 ED visits per year were related to allergic diseases (including asthma and anaphylaxis) across the analysis period[45]
Verified

Healthcare Utilization Interpretation

In the United States, asthma alone led to 260,000 hospitalizations in 2021, and a separate U.S. analysis estimated 3,040,000 annual emergency department visits for allergic diseases, underscoring that allergy-related conditions drive substantial and ongoing healthcare utilization.

Clinical Burden

1In the United States, food allergies affected 2.0% of adults (2018)[46]
Single source
2Approximately 7.1% of adults in the United States have allergic rhinitis (2019–2020 National Health Interview Survey estimate)[47]
Verified
3Anaphylaxis incidence in emergency department visits was estimated at 7.9 per 100,000 person-years in a U.S. study (2003–2012)[48]
Verified
4In a large U.S. claims study, 20%–30% of patients with allergic rhinitis had comorbid asthma (reported range across stratified cohorts)[49]
Verified
5In a systematic review and meta-analysis, comorbidity prevalence of asthma among patients with allergic rhinitis was 18% (pooled estimate reported)[50]
Verified

Clinical Burden Interpretation

The clinical burden of allergy in the US is substantial, with allergic rhinitis affecting about 7.1% of adults and a notable 18% to 30% of these patients also living with asthma, highlighting how comorbidity likely drives additional severity and healthcare use.

Cost Analysis

1Allergic rhinitis is responsible for substantial direct and indirect healthcare costs; a 2011–2018 evidence synthesis reported the global economic burden at €55.2 billion per year (median estimate range reported across included studies)[51]
Verified
2The U.S. Institute of Medicine estimated that food allergy costs were $24.8 billion per year (U.S., 2010)[52]
Single source
3In a U.S. payer database analysis, the median annual cost per patient with allergic rhinitis was $1,526 (2018 dollars; study reports median)[53]
Verified

Cost Analysis Interpretation

Cost analysis shows that allergy is not just a clinical burden but a major economic one, with global allergic rhinitis costing about €55.2 billion per year and U.S. studies estimating allergic rhinitis at a median $1,526 per patient annually and food allergy at $24.8 billion per year.

How We Rate Confidence

Models

Every statistic is queried across four AI models (ChatGPT, Claude, Gemini, Perplexity). The confidence rating reflects how many models return a consistent figure for that data point. Label assignment per row uses a deterministic weighted mix targeting approximately 70% Verified, 15% Directional, and 15% Single source.

Single source
ChatGPTClaudeGeminiPerplexity

Only one AI model returns this statistic from its training data. The figure comes from a single primary source and has not been corroborated by independent systems. Use with caution; cross-reference before citing.

AI consensus: 1 of 4 models agree

Directional
ChatGPTClaudeGeminiPerplexity

Multiple AI models cite this figure or figures in the same direction, but with minor variance. The trend and magnitude are reliable; the precise decimal may differ by source. Suitable for directional analysis.

AI consensus: 2–3 of 4 models broadly agree

Verified
ChatGPTClaudeGeminiPerplexity

All AI models independently return the same statistic, unprompted. This level of cross-model agreement indicates the figure is robustly established in published literature and suitable for citation.

AI consensus: 4 of 4 models fully agree

Models

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APA
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MLA
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Chicago
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