GITNUX REPORT 2024

Examining Americas Most Dangerous Drugs: Overdose Deaths and Risks

Exploring the Deadly Grip of Most Dangerous Drugs: From Heroin to Fentanyl, Alarming Realities Revealed.

Author: Jannik Lindner

First published: 7/17/2024

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Benzodiazepines were involved in 16% of opioid overdose deaths in 2019

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Alcohol is responsible for 95,000 deaths annually in the US

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Benzodiazepines were involved in 9,711 overdose deaths in 2019

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Alcohol contributes to about 18.5% of emergency department visits

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Benzodiazepine misuse is highest among adults aged 18-25

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Long-term alcohol abuse can lead to a 3-fold increase in risk of dementia

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Benzodiazepine overdose deaths increased 8-fold from 1999 to 2017

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Chronic alcohol use can lead to a 3-fold increase in risk of liver cancer

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Long-term benzodiazepine use is associated with a 50% increased risk of dementia

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Alcohol is responsible for 5.3% of all deaths worldwide

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Chronic benzodiazepine use is associated with a 25% increased risk of hip fracture in older adults

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Alcohol use is responsible for 18.5% of emergency department visits in the US

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LSD use among 12th graders increased from 2% in 2016 to 3.6% in 2020

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MDMA (Ecstasy) can increase body temperature to 106°F or higher

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PCP can cause violent behavior and psychosis at high doses

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MDMA can cause long-lasting brain damage affecting thought and memory

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LSD can cause persistent psychosis in some users

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PCP can cause seizures, coma, and death

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MDMA can cause severe dehydration and electrolyte imbalance

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LSD can cause Hallucinogen Persisting Perception Disorder (HPPD)

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MDMA use is associated with a 9-fold increase in risk of cognitive impairment

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PCP use can lead to severe memory loss and cognitive deficits

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LSD use can lead to severe, long-lasting anxiety disorders

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MDMA use is associated with a 7-fold increase in risk of sleep apnea

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LSD use can cause persistent visual disturbances in up to 4.2% of users

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Heroin is responsible for 14,019 overdose deaths in the US in 2019

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Fentanyl is 50 to 100 times more potent than morphine

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Prescription opioids were involved in 14,139 overdose deaths in 2019

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About 1 in 5 people who begin abusing prescription opioids eventually transition to heroin

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Kratom has been linked to at least 91 overdose deaths

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Synthetic opioids, including fentanyl, were involved in 36,359 overdose deaths in 2019

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Heroin use increased 63% between 2002 and 2013

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Fentanyl is involved in more than 50% of opioid-related deaths in some states

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Heroin use more than doubled among young adults aged 18-25 in the past decade

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Fentanyl is detected in more than 50% of opioid overdose deaths in 10 states

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Heroin use increased among women by 100% between 2002 and 2013

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Fentanyl is 100 times more potent than morphine

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Heroin use is associated with a 3-fold increase in risk of getting HIV

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Fentanyl overdose deaths increased by 1,125% between 2011 and 2017

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Cocaine was involved in 1 in 5 overdose deaths in 2019

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Methamphetamine use has increased 43% between 2015 and 2019

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Methamphetamine-related overdose deaths increased 7.5-fold between 2007 and 2017

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Cocaine overdose deaths increased by 26.5% from 2016 to 2017

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Methamphetamine use is associated with a 2.4-fold increased risk of Parkinson's disease

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Cocaine use can lead to a 7-fold increase in stroke risk in young adults

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Methamphetamine was involved in 16,167 overdose deaths in 2019

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Cocaine use can lead to a 6-fold increase in risk of heart attack

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Methamphetamine use is associated with a 4-fold increase in risk of psychosis

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Cocaine use is associated with a 2-fold increase in risk of suicidal behavior

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Methamphetamine use is associated with a 3-fold increase in risk of dental problems

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Cocaine use is associated with a 6-fold increase in risk of aortic dissection

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Methamphetamine use is associated with a 2-fold increase in risk of stroke

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Cocaine use is associated with a 4-fold increase in risk of sudden cardiac death

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Synthetic cannabinoids (K2/Spice) were responsible for 151 deaths in 2019

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Bath salts (synthetic cathinones) can cause severe paranoia and violent behavior

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Synthetic cannabinoids can be 2-100 times more potent than THC

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Bath salts were involved in 0.4% of drug-related emergency department visits in 2011

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Synthetic cannabinoids have been linked to acute kidney injury

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Bath salts can cause severe paranoia and psychotic episodes

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Synthetic cannabinoids can cause severe bleeding disorders

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Synthetic cannabinoids were responsible for 7,600 poison control center calls in 2015

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Bath salts use is associated with a 16-fold increase in risk of emergency department visits

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Synthetic cannabinoids can cause acute kidney injury in 16% of users

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Bath salts use is associated with a 3-fold increase in risk of death compared to other stimulants

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Summary

  • Heroin is responsible for 14,019 overdose deaths in the US in 2019
  • Fentanyl is 50 to 100 times more potent than morphine
  • Cocaine was involved in 1 in 5 overdose deaths in 2019
  • Methamphetamine use has increased 43% between 2015 and 2019
  • Benzodiazepines were involved in 16% of opioid overdose deaths in 2019
  • LSD use among 12th graders increased from 2% in 2016 to 3.6% in 2020
  • MDMA (Ecstasy) can increase body temperature to 106°F or higher
  • Alcohol is responsible for 95,000 deaths annually in the US
  • Prescription opioids were involved in 14,139 overdose deaths in 2019
  • Methamphetamine-related overdose deaths increased 7.5-fold between 2007 and 2017
  • About 1 in 5 people who begin abusing prescription opioids eventually transition to heroin
  • Cocaine overdose deaths increased by 26.5% from 2016 to 2017
  • Benzodiazepines were involved in 9,711 overdose deaths in 2019
  • PCP can cause violent behavior and psychosis at high doses
  • Synthetic cannabinoids (K2/Spice) were responsible for 151 deaths in 2019

If you thought playing with fire was dangerous, wait until you hear about the most lethal dance partners in town. In a world where the grim reapers playlist includes a deadly mix of symphonies conducted by heroin, fentanyl, cocaine, methamphetamine, and an ensemble cast of other lethal substances, the music of mortality plays a haunting tune. From fateful overdoses to harrowing health risks, these substances have turned the party scene into a perilous playground. So, grab your hazmat suit and join us as we delve into the deadly world of the most dangerous drugs around.

Depressants

  • Benzodiazepines were involved in 16% of opioid overdose deaths in 2019
  • Alcohol is responsible for 95,000 deaths annually in the US
  • Benzodiazepines were involved in 9,711 overdose deaths in 2019
  • Alcohol contributes to about 18.5% of emergency department visits
  • Benzodiazepine misuse is highest among adults aged 18-25
  • Long-term alcohol abuse can lead to a 3-fold increase in risk of dementia
  • Benzodiazepine overdose deaths increased 8-fold from 1999 to 2017
  • Chronic alcohol use can lead to a 3-fold increase in risk of liver cancer
  • Long-term benzodiazepine use is associated with a 50% increased risk of dementia
  • Alcohol is responsible for 5.3% of all deaths worldwide
  • Chronic benzodiazepine use is associated with a 25% increased risk of hip fracture in older adults
  • Alcohol use is responsible for 18.5% of emergency department visits in the US

Interpretation

In a world where statistics often speak louder than words, the numbers surrounding the most dangerous drugs paint a grim picture of the toll they take on society. From benzodiazepines shadowed by the opioid crisis and their alarming rise in overdose deaths, to alcohol's staggering annual death toll and its ubiquitous presence in emergency departments, the reality is stark. The youthful allure of benzodiazepine misuse juxtaposed with the long-term risks of dementia, mirrors the deceptive charm of alcohol, promising momentary escape but delivering long-lasting consequences. As the numbers climb, so does the urgency for awareness, education, and intervention in the face of these perilous substances that claim lives and shatter families.

Hallucinogens

  • LSD use among 12th graders increased from 2% in 2016 to 3.6% in 2020
  • MDMA (Ecstasy) can increase body temperature to 106°F or higher
  • PCP can cause violent behavior and psychosis at high doses
  • MDMA can cause long-lasting brain damage affecting thought and memory
  • LSD can cause persistent psychosis in some users
  • PCP can cause seizures, coma, and death
  • MDMA can cause severe dehydration and electrolyte imbalance
  • LSD can cause Hallucinogen Persisting Perception Disorder (HPPD)
  • MDMA use is associated with a 9-fold increase in risk of cognitive impairment
  • PCP use can lead to severe memory loss and cognitive deficits
  • LSD use can lead to severe, long-lasting anxiety disorders
  • MDMA use is associated with a 7-fold increase in risk of sleep apnea
  • LSD use can cause persistent visual disturbances in up to 4.2% of users

Interpretation

It seems like the lineup for the "Most Dangerous Drug" award is quite competitive these days, with LSD, MDMA, and PCP each showcasing their unique talents in wreaking havoc on the human brain and body. From LSD's induction into the Hallucinogen Persisting Perception Disorder hall of fame to MDMA's dangerous dance with cognitive impairment, and PCP's chilling performance as the Grim Reaper of memory, it's no wonder they're stealing the spotlight. With risks including persistent psychosis, brain damage, violent behavior, and even death, it's no surprise that these substances are making a name for themselves in the dangerous drug world. Keep your seatbelts fastened and your brain cells intact, folks - this show is not for the faint of heart.

Opioids

  • Heroin is responsible for 14,019 overdose deaths in the US in 2019
  • Fentanyl is 50 to 100 times more potent than morphine
  • Prescription opioids were involved in 14,139 overdose deaths in 2019
  • About 1 in 5 people who begin abusing prescription opioids eventually transition to heroin
  • Kratom has been linked to at least 91 overdose deaths
  • Synthetic opioids, including fentanyl, were involved in 36,359 overdose deaths in 2019
  • Heroin use increased 63% between 2002 and 2013
  • Fentanyl is involved in more than 50% of opioid-related deaths in some states
  • Heroin use more than doubled among young adults aged 18-25 in the past decade
  • Fentanyl is detected in more than 50% of opioid overdose deaths in 10 states
  • Heroin use increased among women by 100% between 2002 and 2013
  • Fentanyl is 100 times more potent than morphine
  • Heroin use is associated with a 3-fold increase in risk of getting HIV
  • Fentanyl overdose deaths increased by 1,125% between 2011 and 2017

Interpretation

The statistics on the most dangerous drugs in the United States read like a terrifying script for a blockbuster thriller, with heroin and fentanyl taking center stage as the deadliest villains. From their deadly potency to their insidious links to overdose deaths, these substances paint a grim picture of the ongoing battle against addiction and its tragic consequences. As the numbers soar and the body count continues to rise, it's clear that this is not just a war on drugs; it's a battle for the very soul of our society. It's time to confront these grim realities head-on and fight for a future where these staggering statistics are just a dark chapter in our history, not a chilling forecast of what's to come.

Stimulants

  • Cocaine was involved in 1 in 5 overdose deaths in 2019
  • Methamphetamine use has increased 43% between 2015 and 2019
  • Methamphetamine-related overdose deaths increased 7.5-fold between 2007 and 2017
  • Cocaine overdose deaths increased by 26.5% from 2016 to 2017
  • Methamphetamine use is associated with a 2.4-fold increased risk of Parkinson's disease
  • Cocaine use can lead to a 7-fold increase in stroke risk in young adults
  • Methamphetamine was involved in 16,167 overdose deaths in 2019
  • Cocaine use can lead to a 6-fold increase in risk of heart attack
  • Methamphetamine use is associated with a 4-fold increase in risk of psychosis
  • Cocaine use is associated with a 2-fold increase in risk of suicidal behavior
  • Methamphetamine use is associated with a 3-fold increase in risk of dental problems
  • Cocaine use is associated with a 6-fold increase in risk of aortic dissection
  • Methamphetamine use is associated with a 2-fold increase in risk of stroke
  • Cocaine use is associated with a 4-fold increase in risk of sudden cardiac death

Interpretation

These statistics paint a grim picture of the dangers associated with cocaine and methamphetamine use. From the soaring rates of overdose deaths to the alarming risks of serious health complications, it's clear that these drugs are not to be taken lightly. The sharp increase in methamphetamine-related deaths and the concerning links to Parkinson's disease, psychosis, and dental problems underscore the urgent need for greater awareness and intervention. As for cocaine, the stark associations with strokes, heart attacks, and suicidal behavior serve as a stark warning: the high may be fleeting, but the consequences are far-reaching and potentially irreversible. In a world full of risks, these statistics are a sobering reminder that some hazards are self-inflicted and entirely avoidable.

Synthetic Drugs

  • Synthetic cannabinoids (K2/Spice) were responsible for 151 deaths in 2019
  • Bath salts (synthetic cathinones) can cause severe paranoia and violent behavior
  • Synthetic cannabinoids can be 2-100 times more potent than THC
  • Bath salts were involved in 0.4% of drug-related emergency department visits in 2011
  • Synthetic cannabinoids have been linked to acute kidney injury
  • Bath salts can cause severe paranoia and psychotic episodes
  • Synthetic cannabinoids can cause severe bleeding disorders
  • Synthetic cannabinoids were responsible for 7,600 poison control center calls in 2015
  • Bath salts use is associated with a 16-fold increase in risk of emergency department visits
  • Synthetic cannabinoids can cause acute kidney injury in 16% of users
  • Bath salts use is associated with a 3-fold increase in risk of death compared to other stimulants

Interpretation

It seems that synthetic cannabinoids and bath salts are engaged in a dangerous game of one-upmanship, each trying to outdo the other in the realm of destructive effects on users. From causing severe paranoia and violent behavior to acute kidney injury and bleeding disorders, these substances are truly a deadly duo. With statistics painting a grim picture of their impact on society, it's clear that dabbling in these potent substances is playing a dangerous game of Russian roulette with your health and well-being. Stick to natural highs, folks; synthetic may be impressive in its potency, but it's certainly not worth the risk.

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