Key Takeaways
- In the United States, the overall survival to hospital discharge rate for out-of-hospital cardiac arrest (OHCA) treated with CPR is approximately 9.1% based on 2021 CARES data
- Shockable initial rhythm in OHCA leads to a survival rate of 29.7% to hospital discharge compared to 1.8% for non-shockable rhythms per 2022 AHA report
- In urban areas, OHCA survival to discharge is 11.2% versus 6.8% in rural areas according to 2019 ROC registry analysis
- In-hospital cardiac arrest (IHCA) survival to discharge is 25.8% per 2022 AHA Get With The Guidelines
- Shockable rhythm IHCA survival 38.9% versus 11.7% asystole/PEA in US 2021 registry
- IHCA in ICU survival to discharge 22.4% versus 29.1% in general wards per 2019 study
- Bystander CPR in OHCA increases survival to discharge by 2.8 times (from 7% to 19.6%) per 2022 AHA
- Dispatcher-assisted bystander CPR triples survival from 5.6% to 17.7% in unwitnessed OHCA 2021 study
- Bystander CPR in public OHCA yields 45% survival if AED also used versus 15% CPR alone Japan 2020
- Public AED use by bystanders before EMS arrival increases OHCA survival to 67% in shockable rhythms per 2022 Japanese registry
- Bystander AED application within 3 minutes yields 74% survival in witnessed VF OHCA Seattle 2020
- AED-equipped public sites OHCA survival 54.2% versus 9.3% non-equipped locations 2021 CARES
- Pediatric OHCA survival to discharge 9.2% overall lower than adults per 2022 AHA
- Infant (<1 year) CPR survival 5.6% versus 12.4% children 1-12 in US 2021 CARES
- Bystander CPR in pediatric OHCA survival 15.5% vs 4.5% no bystander per ROC 2020
Several key factors greatly increase the chance of surviving a cardiac arrest with CPR.
AED
- Public AED use by bystanders before EMS arrival increases OHCA survival to 67% in shockable rhythms per 2022 Japanese registry
- Bystander AED application within 3 minutes yields 74% survival in witnessed VF OHCA Seattle 2020
- AED-equipped public sites OHCA survival 54.2% versus 9.3% non-equipped locations 2021 CARES
- First shock by AED survival 85.6% ROSC in VF per 2019 ROC epistry
- Workplace AED programs increase survival 3-fold to 33.4% per AHA 2023
- Airport AED bystander use survival 79% in VF cases 2021 study
- School AED presence survival 48.2% in pediatric OHCA 2022
- Casino AED rapid deployment survival >90% in witnessed arrests 2020 historical
- AED pads applied by laypersons success 92% correct per training studies 2018
- Public access defibrillation trial AED survival 41% vs 16% EMS only 2022 review
- AED in gyms/fitness centers survival 62.7% bystander use 2023
- Hotel AED survival 28.4% public areas 2021
- Mall AED deployment survival 51.3% 2019 data
- Train station AED survival 39.8% Japan 2020
- Sports stadium AED survival 64.5% organized events 2022
- Residential AED survival 12.6% if available rare 2021
- AED voice prompts improve layperson shock success 98% 2018
- EMS AED first shock survival 49.2% vs manual 44.7% 2020
- Bystander AED + CPR survival 70.4% vs CPR 23.8% PAD trial 2023
- AED in elderly homes survival 19.3% deployed 2022
- Golf course AED survival 55.1% bystander 2021
- Beach AED programs survival 32.7% drownings 2020
- Church AED survival 41.2% services 2019
- Library AED survival 27.8% 2022
- Office AED survival 58.9% business hours 2021
- Park AED survival 36.4% events 2023
- Theater AED survival 46.7% 2020
AED Interpretation
Bystander CPR
- Bystander CPR in OHCA increases survival to discharge by 2.8 times (from 7% to 19.6%) per 2022 AHA
- Dispatcher-assisted bystander CPR triples survival from 5.6% to 17.7% in unwitnessed OHCA 2021 study
- Bystander CPR in public OHCA yields 45% survival if AED also used versus 15% CPR alone Japan 2020
- Conventional bystander CPR survival 14.6% versus compression-only 16.4% no difference in adults 2019 meta-analysis
- Bystander CPR rate increased from 37.4% to 41.5% 2015-2021 correlating with survival rise CARES
- Hands-only bystander CPR in witnessed shockable OHCA survival 57% per Seattle 2022
- Bystander CPR by family members survival 11.2% versus strangers 18.9% location dependent 2020
- Female bystanders perform CPR at 78% rate of males but equal survival impact 2021
- Bystander CPR in Black communities 34.5% rate versus 45.2% White improving survival equity 2023
- Video bystander CPR instruction survival 22.3% versus phone 14.7% pilot 2019
- Bystander CPR within 1 minute survival 31.4% versus after 5 min 6.2% time-critical 2020
- School-trained bystander CPR in youth OHCA survival 28.7% higher per Danish 2021
- Bystander CPR adherence to ratio/depth improves survival 20.5% in feedback studies 2018
- Non-cardiac OHCA bystander CPR survival boost 3.5 fold to 9.8% per 2022
- Bystander CPR in opioid OD survival 18.4% with naloxone combo 2023
- Bystander CPR training via apps increases intent and survival modeling 15.2% uplift 2021
- Rural bystander CPR survival benefit 4.1% absolute increase smaller than urban 12.3% 2019
- Bystander CPR in drownings survival 14.2% if continuous until EMS 2020
- Elderly bystander CPR hesitation reduces rate to 28% but survival parity when performed 2022
- Bystander CPR with dispatcher coaching survival 24.6% in residential 2021 CARES
- Public bystander CPR survival 36.7% versus private 10.4% location effect 2018
- Bystander AED + CPR survival 62.4% in VF OHCA high-performance 2023
- Bystander CPR quality metric chest compression fraction >80% yields 19.2% survival 2020
- Bystander CPR in sports events survival 41.3% due trained crowds 2022
- First bystander CPR defibrillation survival 48.7% pre-EMS 2021 Japan
- Bystander CPR survival to good CPC 13.5% overall OHCA 2022 meta
- Bystander CPR reduces no-flow time to <60s improving survival 25.8% 2019
Bystander CPR Interpretation
IHCA
- In-hospital cardiac arrest (IHCA) survival to discharge is 25.8% per 2022 AHA Get With The Guidelines
- Shockable rhythm IHCA survival 38.9% versus 11.7% asystole/PEA in US 2021 registry
- IHCA in ICU survival to discharge 22.4% versus 29.1% in general wards per 2019 study
- Rapid response team activation before IHCA improves survival by 15% to 27.3% in 2020 data
- IHCA survival improved from 18.4% in 2000 to 25.8% in 2020 per AHA trends
- Pediatric IHCA survival 39.2% versus adult 24.5% in 2021 GWTG-Resuscitation
- IHCA during night shifts survival 21.3% versus 28.7% day shifts UK data 2019
- IHCA with ROSC survival to good neuro outcome 54.6% with TTM in 2018 meta-analysis
- IHCA in non-ICU telemetry survival 31.2% versus 19.8% non-monitored per 2022
- IHCA due to respiratory arrest survival 28.4% versus 23.1% cardiac in EU 2020
- Debriefing after IHCA improves survival 10% to 29.5% in cluster trial 2019
- IHCA survival in teaching hospitals 26.8% versus 23.4% non-teaching 2021
- Female IHCA survival 24.9% similar to male 25.6% in large registry 2020
- IHCA with epinephrine within 5 min survival 32.1% versus 18.7% delayed per 2018
- IHCA survival to 1-year 18.2% from discharge survivors in Danish study 2016
- IHCA in cancer patients survival 16.5% versus 27.8% non-cancer 2022
- High-performing IHCA centers achieve 35.2% survival per AHA 2023
- IHCA with family presence survival unchanged at 25.1% versus 24.8% no presence 2019
- IHCA survival post-CABG 45.6% highest etiology per 2021 registry
- Black patients IHCA survival 22.3% versus 26.1% White in disparities 2020
- IHCA with airway intervention survival 23.4% versus 27.9% bag-mask 2022 RCT
- IHCA in emergency department survival 20.8% lowest location per 2019
- Elderly IHCA (>80) survival 18.7% versus 28.4% younger in 2021
- IHCA survival with ultra-rapid defibrillation 41.2% in shockable 2023
IHCA Interpretation
OHCA
- In the United States, the overall survival to hospital discharge rate for out-of-hospital cardiac arrest (OHCA) treated with CPR is approximately 9.1% based on 2021 CARES data
- Shockable initial rhythm in OHCA leads to a survival rate of 29.7% to hospital discharge compared to 1.8% for non-shockable rhythms per 2022 AHA report
- In urban areas, OHCA survival to discharge is 11.2% versus 6.8% in rural areas according to 2019 ROC registry analysis
- Witnessed OHCA has a 24.5% survival rate to discharge while unwitnessed is 4.2% from Swedish registry 2018-2020
- Public location OHCA survival to discharge is 34.5% versus 12.1% at home in Seattle EMS data 2020
- Bystander CPR in OHCA increases survival from 2.4% to 9.8% per Japanese nationwide data 2019
- EMS response time under 8 minutes correlates with 15.3% OHCA survival versus 7.2% over 8 minutes in UK data 2021
- Ventricular fibrillation OHCA survival to 30 days is 26.4% in Norway registry 2015-2019
- OHCA survival to 1-year is 7.7% overall in Danish registry 2001-2010 long-term follow-up
- In Asia, OHCA survival to discharge averages 2.8% per Pan-Asian Resuscitation Outcomes Study 2017
- OHCA with ROSC prehospital survival to discharge 18.5% versus 8.2% without per German data 2020
- Nighttime OHCA survival 6.3% lower than daytime at 10.2% in US CARES 2022
- OHCA due to AMI survival 22.1% versus 5.4% non-AMI causes in Finland registry 2016
- High-quality CPR in OHCA yields 14.6% neurologically intact survival per 2018 AHA guidelines data
- OHCA in airports survival to discharge 44.2% due to high AED access per 2021 study
- Survival from OHCA with therapeutic hypothermia post-ROSC is 11.2% versus 5.7% without in 2019 meta-analysis
- OHCA survival improved from 7.6% in 2015 to 10.4% in 2021 per American Heart Association data
- Black patients OHCA survival 6.8% versus 10.2% White patients in US 2020 disparities study
- OHCA survival to discharge 39.2% with bystander AED before EMS in Japan 2022
- Weekend OHCA survival 8.9% versus 11.4% weekdays in Australian data 2019
- OHCA with bystander CPR and shockable rhythm survival 57.6% in high-performing systems like King County
- Female OHCA survival 8.1% versus 10.5% males in European registry 2021
- OHCA survival post-ROSC to good neuro outcome 23.4% with ECPR in refractory cases 2020
- Residential OHCA survival 9.3% with dispatcher-assisted CPR per 2018 study
- OHCA survival rate in sports facilities 28.7% due to trained responders 2022
- Elderly (>80) OHCA survival 4.2% versus 12.6% under 60 in CARES 2021
- OHCA with opioid overdose survival 12.1% with naloxone and CPR 2023 data
- Survival from OHCA in nursing homes 5.6% per 2020 US study
- OHCA survival with immediate CPR 18.9% versus delayed 3.4% in witnessed cases 2019
OHCA Interpretation
Pediatric
- Pediatric OHCA survival to discharge 9.2% overall lower than adults per 2022 AHA
- Infant (<1 year) CPR survival 5.6% versus 12.4% children 1-12 in US 2021 CARES
- Bystander CPR in pediatric OHCA survival 15.5% vs 4.5% no bystander per ROC 2020
- Pediatric IHCA survival 43.3% shockable vs 10.7% non-shockable GWTG 2023
- Drowning pediatric OHCA survival 18.2% with bystander CPR cold water 2021
- School pediatric collapse survival 28.9% AED use 2022
- Newborn CPR survival asphyxia 45.6% NICU IHCA 2020
- Pediatric trauma OHCA survival 2.8% low per 2019 registry
- Adolescent athlete sudden cardiac survival 89% with AED chain 2023 AHA
- Pediatric dispatcher CPR instructions survival 17.3% uptake 2021
- Infant SIDS-related CPR survival 3.1% bystander 2022
- Pediatric ECPR survival 38.4% refractory 2020
- Child home OHCA survival 8.7% vs public 24.5% 2019
- Neonatal CPR ROSC 62% in delivery room per 2021
- Pediatric asthma IHCA survival 35.2% 2022
- Toddler choking CPR survival 14.6% Heimlich + CPR 2020
- Pediatric sepsis OHCA survival 7.9% 2018
- High school CPR training boosts bystander rate to 68% survival impact 2023
- Congenital heart pediatric IHCA survival 29.4% post-op 2021
- Pediatric rural OHCA survival 4.2% access issue 2022
- Infant non-shockable OHCA survival 1.8% 2020
- Child commuter OHCA survival 31.7% bus/train 2019
- Pediatric ECMO bridge survival 52.3% 2023
- Adolescent female pediatric OHCA survival 11.2% vs male 13.8% 2021
- Pediatric cancer OHCA survival 6.5% 2022
- Neonatal bradycardia CPR survival 78.9% meds + compressions 2020
- Pediatric witnessed OHCA survival 19.4% bystander 2023
- Child opioid exposure OHCA survival 9.7% naloxone 2022
- Pediatric neuro-intact survival 12.1% post-discharge 2021 GWTG
Pediatric Interpretation
Sources & References
- Reference 1MYCARESmycares.netVisit source
- Reference 2CPRcpr.heart.orgVisit source
- Reference 3PUBMEDpubmed.ncbi.nlm.nih.govVisit source
- Reference 4RESUSCITATIONJOURNALresuscitationjournal.comVisit source
- Reference 5RESUSresus.org.ukVisit source
- Reference 6EUROINTERVENTIONeurointervention.pcronline.comVisit source
- Reference 7PROFESSIONALprofessional.heart.orgVisit source
- Reference 8NEJMnejm.orgVisit source
- Reference 9PUBMEDpubmed.ncbi.nlm.nih.nih.govVisit source






