01Left-handedness increases from about 8% in older age groups to about 11% in younger cohorts in several European surveys
0286% of left-handers show right-hemisphere language dominance compared with about 98% of right-handers
03Up to 30% of left-handed people display atypical language lateralization
0440–60% of left-handers have less consistent cerebral lateralization than right-handers, as summarized in a neuroimaging review
05Left-handers have a higher rate of reduced corpus callosum volume by about 5–10% in some MRI studies
06Diffusion MRI studies reported about a 7% difference in fractional anisotropy in the arcuate fasciculus between left-handers and right-handers
07A 2016 meta-analysis found left-handers are 1.3 times more likely to show atypical brain lateralization
08A 2013 review reported that 15–25% of left-handers have motor cortex activation patterns different from right-handers during handedness tasks
09In a functional MRI task study, left-handers had about 20% less lateralization index for language-related activation than right-handers
10A study using fMRI reported that 33% of left-handers had bilateral activation during speech tasks
11Left-handers show a higher frequency (~2x) of mixed handedness-related motor responses in some sensorimotor tasks
12A 2010 study found that left-handers performed 5–8% faster on some visuospatial tasks compared with right-handers
13In a large cognitive battery, left-handers scored about 0.2 SD higher on mental rotation accuracy (meta-analytic estimate)
14A 2014 meta-analysis estimated a small but significant advantage for left-handers in visuospatial ability (effect size g≈0.10)
15Left-handers have about a 1.4× increased likelihood of being in the left-tail of reaction time variability in some datasets (SD-based metric)
16A resting-state fMRI study reported that left-handers had ~10% greater functional connectivity strength between certain fronto-parietal networks
17An event-related potential study found left-handers had a ~15 ms longer P300 latency than right-handers (auditory oddball task)
18A 2009 EEG study found alpha power differences of about 5–10% between left- and right-handers during resting state
19Left-handers show about 1.2× greater likelihood of being diagnosed with developmental coordination disorder in a cohort study
20In a 2012 study, left-handers had a 0.17 SD lower performance on certain verbal fluency measures
21A 2015 UK Biobank-based analysis linked left-handedness with a 1.1× increase in risk of schizophrenia diagnosis (odds ratio)
22Left-handers have about a 1.3× increased odds of autism spectrum disorder in a meta-analysis (OR)
23In a neuropsychology dataset, left-handers showed about a 2-point higher mean score on the Trail Making Test Part B interference metric
24A 2008 study found that left-handers were 1.5× more likely to show atypical motor learning patterns in mirror drawing
25Left-handedness is associated with about a 1.2× increased prevalence of epilepsy in a cohort study (risk ratio)
26A 2017 systematic review reported left-handers are 1.25× more likely to have attention deficit/hyperactivity disorder
27Left-handers show about a 1.3× higher rate of developmental language disorder in a population study
28A 2020 EEG study found that left-handers had ~8% higher theta-band power during cognitive control tasks
29A 2019 fMRI paper reported left-handers had about 12% less hemispheric specialization index for spatial attention tasks
30Left-handers show a higher frequency (~20%) of bilateral activation in somatosensory cortex during tactile tasks