GITNUX MARKETDATA REPORT 2024
Hsil To Cancer Progression Timeframe Statistics
There is considerable variability in the progression timeframe from HSIL to cancer, with some cases progressing within a few years while others may remain stable for a long period of time.
In this post, we will explore key statistics related to the progression of high-grade squamous intraepithelial lesions (HSIL) to invasive cervical cancer. With approximately 30% of women with untreated HSIL at risk of developing cervical cancer, understanding the average progression timeframe of 10 to 12 years is crucial. Additionally, we will discuss the prevalence of HSIL, the risks associated with HSIL development, the impact of high-risk HPV, and more, providing valuable insights into this important health issue.
Statistic 1
"Approximately 30% of women with high-grade squamous intraepithelial lesions (HSIL) may progress to invasive cervical cancer if left untreated."
Statistic 2
"The average time for HSIL to progress to invasive cervical cancer is about 10 to 12 years."
Statistic 3
"Studies suggest that up to 1% of women have HSIL at any time."
Statistic 4
"HSIL has an absolute risk of progressing into cervical cancer from 3% to 4% in one year and 7% to 9% in two years post diagnosis."
Statistic 5
"Nearly 2% of HSIL cases may have underlying invasive cancer."
Statistic 6
"Only about 5% of women with HSIL actually have cervical cancer."
Statistic 7
"The median time from normal PAP to HSIL formation is 3 years."
Statistic 8
"The absolute 2-year and 5-year risks of HSIL development into carcinoma can go up to 19% and 40% respectively."
Statistic 9
"Women with HSIL and high-risk HPV have 7 times higher risk of cervical cancer."
Statistic 10
"80% of women will get an HPV infection (common cause of HSIL) by age 50."
Statistic 11
"A long interval, on average 10.4 years, separates development of HSIL from invasive carcinoma."
Statistic 12
"Among women with HSIL, the prevalence of underlying cervical intraepithelial neoplasia grade 2 is very high, 88.2%."
Statistic 13
"Patients who had HSIL on histology had a cumulative risk of treatment failure of 16.2% at 24 months."
Statistic 14
"Over 8 years, the incidence of HSIL+ was 14.7 per 1000, but the cumulative incidence of cervical cancer was 1.3 per 1000."
Jannik Lindner
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