Haldol Duration Statistics

In this post, we explore the pharmacokinetics and clinical usage of Haldol, a commonly prescribed antipsychotic medication. From its absorption and elimination half-life to prescribing trends and administration methods, we delve into key statistics surrounding Haldol’s duration of action and impact on patient care.

Statistic 1

"Haldol is rapidly absorbed after oral administration (though its bioavailability is only about 60% due to first-pass metabolism)."

Statistic 2

"The mean elimination half-life (t1/2) of oral Haldol in healthy (younger than 65 years) subjects was 20.7 hours."

Statistic 3

"In elderly patients, the elimination half-life can increase to 37 hours."

Statistic 4

"80% of the oral dose is excreted in urine and 15% in feces."

Statistic 5

"A study found that the average dose for patients receiving haloperidol decanoate injections was 141.6 mg."

Statistic 6

"According to a survey, approximately 60% of psychiatrists report using haloperidol to treat delirium."

Statistic 7

"Haldol was originally approved by the FDA in 1967."

Statistic 8

"An approximated 59,000 prescriptions for haloperidol were filled in the US in 2017."

Haldol, a commonly used medication for various psychiatric conditions, exhibits significant variations in absorption, elimination, and prescribing patterns. The drug is rapidly absorbed but with reduced bioavailability due to first-pass metabolism, with longer elimination half-lives observed in elderly patients. Despite its long history since FDA approval in 1967 and relatively high prescription rates, there is a gap in the available statistics for further interpretation. The diverse pharmacokinetic profile and wide utilization of Haldol underscore the importance of ongoing research and monitoring of its clinical use for optimal patient care.