01 Industry overview
The dental bone graft industry at a glance
The global dental bone grafts and substitutes market was valued at $901.1 million in 2025 and is forecast to reach $1.78 billion by 2033, driven by implant procedures and regenerative dentistry.
- $901.1M[16]
- Global market size, 2025
- 9.1%[16]
- Forecast CAGR, 2026–2033
- 38.3%[16]
- North America share, 2025
- $2.33B[27]
- Biomaterials market size, 2025
- Market size
- Grand View Research estimates the global dental bone grafts and substitutes market at $901.1 million in 2025 and $973.1 million in 2026. A narrower dental bone graft substitutes definition produces a 2025 estimate of $328.14 million from Fortune Business Insights.[16][50]
- Forecast & CAGR
- Grand View Research forecasts growth from $973.1 million in 2026 to $1.7849 billion in 2033, representing a 9.1% CAGR. Fortune Business Insights forecasts the substitutes-only market to reach $612.03 million by 2034 at a 7.23% CAGR.[16][50]
- Market share & regions
- North America accounted for 38.3% of global dental bone grafts and substitutes revenue in 2025 according to Grand View Research. In the narrower substitutes market, Fortune Business Insights reports a 47.93% North American share in 2025.[16][50]
- Segmentation
- Products are commonly segmented by material into allografts, xenografts and synthetic grafts; Fortune Business Insights additionally identifies demineralized bone matrix. The market is also segmented by form, including granules and putty, and by end user, including solo practices and dental service organization or group practices.[16][50]
- Key players & concentration
- iData Research identifies Geistlich Pharma, Henry Schein and ZimVie as the three leading dental bone graft companies in 2026, with Geistlich ranked first in dental bone graft substitutes and barrier membranes. The source does not disclose a combined top-three percentage share.[27]
- Pricing
- Geistlich’s U.S. 2025 price list shows Bio-Oss xenograft pricing from $76 for 0.125 g to $1,112 for 5 g, while a 0.5 g product is listed at $167. These are list prices for graft material and do not represent the full patient charge, which can also include surgery, anesthesia and imaging.[51]
- Trends, drivers & challenges
- Market growth is linked to aging populations, tooth loss, periodontal disease and rising dental implant use, which increase demand for ridge augmentation, sinus elevation and extraction-site preservation. Key challenges include regulatory evidence requirements, clinical variability, biological-material sourcing and competition from lower-cost synthetic substitutes.[16][52]
- Consumer behavior & competition
- Demand is primarily clinician-led: dentists, periodontists and oral surgeons select materials based on defect type, handling, evidence, resorption characteristics and compatibility with implant treatment. Competition spans established regenerative brands and synthetic-material specialists; iData Research names Geistlich Pharma, Henry Schein and ZimVie among the leading companies in 2026.[27][16]
- M&A
- Recent consolidation includes Nobel Biocare’s acquisition of Versah, announced February 9, 2026, adding osseodensification and implant-site preparation products to its regenerative portfolio. Lifco also agreed to acquire a majority stake in Ethoss Regeneration, which reported approximately £5.4 million in sales for the year ended July 2025 and was expected to be consolidated in the first quarter of 2026.[53][54]
- Regulation
- In the United States, dental bone grafting material devices are generally Class II devices under 21 CFR 872.3930 and are subject to special controls and 510(k) requirements. FDA guidance covers materials such as hydroxyapatite, tricalcium phosphate, polylactic and polyglycolic acids, and collagen; products containing therapeutic biologics can fall under Class III requirements.[52]
- Latest news
- In August 2026, Isto Biologics announced the acquisition of NovaBone Products from Halma. NovaBone develops synthetic bioactive-glass bone grafts sold in more than 40 countries and used across dental, orthopedic, trauma and other surgical procedures.[55]
02 Ranking
Top 9 Companies in the Dental Bone Graft Industry
The leading companies in the dental bone graft industry, ranked on market impact, performance, momentum, innovation and brand popularity.
Updated November 11, 2026 · Next review December 11, 2026
Straumann Group leads Gitnux's 2026 dental bone graft ranking with an Overall score of 9.7, with operating margin 21.1% and revenue growth 4.1%. Zimmer Biomet is the runner-up at 9.1, backed by revenue growth 7.2% and operating margin 13.3%.
Ranked by Overall score · How we score ↓
Editor's top 3 picks
Where to start, by need.
#1 Overall · #1 overall
Straumann Group
CH
Ranked #1 · 9.7 · Dental implants, biomaterials and bone regeneration
Why we picked it: Biomaterials portfolio includes Bio-Oss and Bio-Gide evidence and labeling for extraction-site and ridge defects.
#2 overall
Zimmer Biomet
US
Ranked #2 · 9.1 · Dental and orthopedic biologics and bone grafts
Why we picked it: Dental bone-graft substitutes supplier with R&D at 5.6% of revenue.
#3 overall
Envista
US
Ranked #3 · 9.0 · Dental implants and regenerative biomaterials
Why we picked it: Regenerative biomaterials and Osteogenics offerings target implant and augmentation workflows.
Pick 1 is the #1 company overall. No other segment places in the top 5, so picks 2 and 3 follow rank.
Full ranking
| # | Company | Overall ↓ | Impact | Company snapshot |
|---|---|---|---|---|
| 1 | Straumann Group Dental implants, biomaterials and bone regeneration · CH | 9.7 | 9.8 | |
Company snapshot · Straumann Group · Data as of November 11, 2026 Straumann researches, manufactures and supplies dental biomaterials for tissue regeneration.[38]
| ||||
| 2 | Zimmer Biomet Dental and orthopedic biologics and bone grafts · US | 9.1 | 9.9 | |
Company snapshot · Zimmer Biomet · Data as of November 11, 2026 Zimmer Biomet is identified as a major dental bone-graft substitutes company.[16]
| ||||
| 3 | Envista Dental implants and regenerative biomaterials · US | 9.0 | 8.8 | |
Company snapshot · Envista · Data as of November 11, 2026 Envista markets dental biomaterials and added Osteogenics regenerative solutions.[56]
| ||||
| 4 | BioHorizons Camlog Group Dental implants, bone grafts and regenerative products | 8.6 | 8.8 | |
Company snapshot · BioHorizons Camlog Group · Data as of November 11, 2026 BioHorizons offers allograft and xenograft bone-grafting products for dental procedures.[57]
| ||||
| 5 | Dentsply Sirona Dental consumables, implants and regenerative products · US | 8.3 | 9.9 | |
Company snapshot · Dentsply Sirona · Data as of November 11, 2026 Dentsply Sirona is listed among major companies in dental bone-graft substitutes.[16]
| ||||
| 6 | Regenity Synthetic and collagen dental bone grafts · US | 8.2 | 7.8 | |
Company snapshot · Regenity · Data as of November 11, 2026 Regenity manufactures collagen membranes and synthetic dental bone-graft substitutes.[58]
| ||||
| 7 | curasan Synthetic dental bone substitutes · DE | 8.2 | 7.8 | |
Company snapshot · curasan · Data as of November 11, 2026 curasan sells OSBONE and CERASORB synthetic grafts for dental augmentation procedures.[59]
| ||||
| 8 | Isto Biologics Allograft and synthetic bone grafts · US | 8.0 | 7.0 | |
Company snapshot · Isto Biologics · Data as of November 11, 2026 Isto expanded its bone-graft platform through the 2026 acquisition of NovaBone.[60]
| ||||
| 9 | ZimVie Dental implants and bone graft biomaterials · US | 7.8 | 8.8 | |
Company snapshot · ZimVie · Data as of November 11, 2026 ZimVie sells RegenerOss grafts for socket, ridge and periodontal defect reconstruction.[61]
| ||||
How we score
- Impact (30%): scale and weight in the market (revenue, market share, employees, market position).
Popularity (brand search demand, 15%) counts toward Overall but is not published as a column. Overall leaves out what is not known.
Scale Scores are shown on a 7–10 scale with one decimal; bars start at 7.0.
Cadence Recalculated when new figures are published; next review December 11, 2026.
Independence. Rankings are editorially independent. Scores, ranks, picks and the verdict follow the method above; no company can pay to change them.
Cite this ranking
APA
Samuel Norberg. (2026, November 11). Top 9 companies in the dental bone graft industry. In Dental Bone Graft Industry Statistics. Gitnux. https://gitnux.org/dental-bone-graft-industry-statistics/#top-companies
03 Trends & forecasts
Top 10 Dental Bone Graft Industry Trends & Forecasts 2027
What is changing in the dental bone graft industry, with the evidence behind each trend and a forecast for 2027.
Forecasts were generated by an AI model from the cited evidence. They are estimates, not guarantees.
01Implant-linked demand continues rising
High confidenceDental bone graft demand remains closely tied to implant-site preparation, socket preservation, ridge augmentation and sinus elevation. Grand View Research reports that the global dental membrane and bone graft substitutes market was valued at $1.6 billion in 2025, with bone graft substitutes the largest and fastest-growing product segment; socket preservation accounted for 27.5% of application revenue.[16]
Forecast 2027: In 2027, implant-related indications should remain the main source of incremental demand, with socket preservation continuing to anchor procedure volume and sinus-lift procedures growing faster from a smaller base.
02Oral disease keeps expanding the patient pool
High confidenceWHO estimates that oral diseases affect nearly 3.7 billion people worldwide. Severe periodontal disease affects more than 1 billion cases and can destroy supporting bone, creating demand for regenerative and reconstructive procedures.[62]
Forecast 2027: Through 2027, periodontal disease and tooth loss should sustain underlying demand, especially in markets where treatment access and restorative care are expanding.
03Older patients support regenerative procedures
High confidenceThe ADA identifies periodontitis, root caries and coronal caries as important dental conditions associated with aging. Its 2026 utilization data show that 53.1% of U.S. seniors had a dental visit in 2023, up from 51.5% in 2022.[63]
Forecast 2027: In 2027, aging demographics should continue increasing the addressable pool for extraction-site preservation, implant preparation and treatment of compromised alveolar bone, although affordability will limit conversion in some populations.
04Synthetic substitutes gain strategic momentum
High confidenceNovaBone’s synthetic bioactive-glass products are sold in more than 40 countries and are used in dental, orthopedic, trauma and other procedures. Isto Biologics acquired NovaBone in August 2026 to expand its portfolio of synthetic bone-graft options and international reach.[55]
Forecast 2027: Synthetic and bioactive-glass products should gain share in 2027 where clinicians prioritize supply consistency, avoiding human or animal tissue, and broader cross-specialty manufacturing scale.
05Premium xenografts retain pricing power
Medium confidenceGeistlich’s U.S. 2025 list price for Bio-Oss ranged from $76 for 0.125 g to $1,112 for 5 g; the 0.5 g product was listed at $167. These are material list prices rather than complete patient charges.[51]
Forecast 2027: In 2027, premium branded xenografts should preserve a price premium in evidence-sensitive procedures, while procurement pressure and synthetic alternatives should constrain broad-based price increases.
06Small-pack and preformed formats expand
High confidenceCommercial portfolios already span granules, collagen-containing products, blocks and putty-like handling formats. Geistlich’s 2025 U.S. list includes Bio-Oss granules from 0.125 g to 5 g, a block product and Bio-Oss Collagen formats, illustrating increasing choice by defect size and handling preference.[51]
Forecast 2027: By 2027, suppliers should continue shifting toward procedure-specific packs, collagen composites, putties and other ready-to-use formats that reduce preparation time and material waste.
07Evidence requirements raise development costs
High confidenceFDA’s dental bone-grafting guidance recommends detailed information on device design, performance testing, biocompatibility, sterilization, labeling, indications and contraindications in 510(k) submissions. The guidance also recommends a sterility assurance level of 10^-6 for sterilized devices.[52]
Forecast 2027: In 2027, regulatory evidence and quality-system requirements should favor established manufacturers and well-funded specialists, while extending launch timelines for products with novel compositions or claims.
08Therapeutic biologics face a higher regulatory bar
High confidenceUnder 21 CFR 872.3930, bone-grafting materials without a therapeutic biologic are Class II devices subject to special controls, while products containing a therapeutic biologic are Class III and require premarket approval.[64]
Forecast 2027: In 2027, companies are likely to favor device-only or carefully bounded combination-product strategies unless the clinical and commercial benefit of adding growth factors or other biologics clearly justifies the additional approval burden.
09Implant and regenerative portfolios converge
High confidenceNobel Biocare announced its acquisition of Versah on February 9, 2026, adding osseodensification and implant-site preparation technology to a portfolio that already includes regenerative solutions. Envista disclosed approximately $54.7 million of consideration for the acquisition.[53][20]
Forecast 2027: In 2027, integrated offerings combining implant systems, site preparation, grafts, membranes and digital planning should increase cross-selling and make portfolio breadth more important in purchasing decisions.
10Consolidation accelerates among specialists
High confidenceThe 2026 Versah transaction and Isto Biologics’ August 2026 acquisition of NovaBone show strategic buyers combining implant-site preparation, biologics and synthetic graft technologies. NovaBone’s products add a bioactive-glass platform and presence across Europe, Asia-Pacific and Latin America.[53][55]
Forecast 2027: Further bolt-on acquisitions are likely in 2027, particularly for bioactive materials, barrier membranes, digital surgery and products that provide access to specialist distributors or overseas markets.
04 Statistics
Technology & Innovation
This section ties manufacturing and digital workflow change to measurable cycle-time and reported efficiency gains. It also logs adoption rates for AI/digital quality work, including 89% in 2020.
Automation in the dental bone graft industry
- 2–3 weeks is the reported production time for personalized, viable BonoFill bone grafts using Bonus BioGroup’s disposable bioreactor system designed for automation, 2025, global.[1]
- 50%+ production-efficiency gains were reported in the first year after dental laboratories implemented Oqton’s AI-driven manufacturing workflow, 2023, global dental-laboratory market.[2]
Digital Transformation in the medical devices sector (sector benchmark)
- Across medtech and IVD professionals worldwide, 87% said their company had implemented or planned to implement AI or digital solutions in regulatory or quality-management systems in 2020.[3]
- Across medtech companies, 36% achieved limited value and no sustainable change from digital transformation in 2021.[4]
- Across medtech companies, 35% created value but failed to meet all digital-transformation targets in 2021.[4]
- Across medtech and IVD professionals worldwide, 89% said their company had implemented or planned to implement AI or digital solutions in its product range in 2020.[3]
- Across medtech companies, 29% met or exceeded their digital-transformation targets with sustainable change in 2021, according to BCG’s global survey.[4]
- Across medtech manufacturing executives, 64% highly prioritized digitizing manufacturing in a 2022 survey.[5]
Technology Adoption in the medical devices sector (sector benchmark)
- Across healthcare industrial-ecosystem SMEs in Europe, 31.0% already used cloud technologies in 2023.[6]
- Across healthcare industrial-ecosystem SMEs in Europe, 13.7% already used artificial intelligence in 2023.[6]
- Among emerging medtech companies, 38% had adopted clinical-trial-management systems, compared with 72% of enterprise and global companies in the 2025 benchmark.[7]
- Among emerging medtech companies, 62% had adopted electronic trial-master-file systems, compared with 89% of enterprise and global companies in the 2025 benchmark.[7]
- Across healthcare industrial-ecosystem SMEs in Europe, 8.6% already used remote patient-monitoring technologies in 2023.[6]
- Across healthcare industrial-ecosystem SMEs in Europe, 17.3% already used robotics in 2023.[6]
Cloud Computing in the medical devices sector (sector benchmark)
- Across medical-device manufacturing respondents in the global Industry Cloud Study, 66% reported that 50%–74% of infrastructure was in the cloud in 2022.[8]
- Across surveyed medtech organizations, 33% reported reliable enterprise-wide use of cloud-based technologies in 2025.[7]
- Across surveyed medtech organizations, 31% managed all postmarket-surveillance processes with cloud-based technology in 2025.[7]
- Across medical-device manufacturing respondents in the global Industry Cloud Study, 21% reported that 75%–100% of infrastructure was in the cloud in 2022.[8]
Big Data in the medical devices sector (sector benchmark)
- 49% of medtech companies reported struggling with untimely data in Model N’s 2025 survey of industry leaders.[9]
- Across medtech and biopharma companies surveyed in 2018, 67% of medtech firms invested in data analytics for reporting.[10]
- 45% was the average share of planned digital-enabler spending that medtech companies allocated to infrastructure, cloud enablement, architecture modernization, and AI and big data, globally, in 2021.[4]
- Across medtech companies surveyed by Model N, nearly 70% already used or planned to use data and analytics in 2023.[9]
- 80% of medtech companies planned to invest in infrastructure, cloud enablement, tech-architecture modernization, and AI and big data, based on a 2021 global survey.[4]
- Across healthcare industrial-ecosystem SMEs in Europe, 15.3% had adopted big data and related data analytics in 2023.[6]
IoT in the medical devices sector (sector benchmark)
- Among healthcare and medical-device IoT respondents, 31% planned to double the number of connected devices deployed in 2023.[11]
- Among European healthcare industrial-ecosystem SMEs already using IoT, 21.4% used predictive maintenance for production assets in 2023.[6]
- Among European healthcare industrial-ecosystem SMEs already using IoT, 22.3% used energy-saving devices such as smart lighting, HVAC or elevators in 2023.[6]
- Among healthcare and medical-device IoT respondents, 9% had deployed between 10,001 and 100,000 connected devices in 2023.[12]
- Across healthcare industrial-ecosystem SMEs in Europe, 20.4% already used Internet of Things technologies in 2023.[6]
- Among healthcare and medical-device IoT respondents, 84% planned to increase their connected-device estate in 2023.[11]
05 Statistics
Data & Analytics
This section highlights data governance and traceability gaps in postmarket and clinical data handling. It also quantifies manual surveillance management: 51% of medical-device companies still do this in the 2025 benchmark.
Data Quality in the medical devices sector (sector benchmark)
- 51% of medical-device companies still managed postmarket-surveillance processes and data manually or partially manually in the 2025 benchmark survey.[7]
- 45.9% of healthcare-sector business partners identified data quality as a major challenge in managing digital product information in the 2021 survey.[13]
- 56% of medical-device companies used non-validated general-purpose tools for clinical data collection in the 2024 MedTech industry survey.[14]
- 73% of medical-device professionals using literature-review software trusted their data quality, compared with 38% using spreadsheets, in a global survey; survey year not stated.[15]
- 60% of medical-device professionals using literature-review software reported data traceability, compared with 4% using spreadsheets, in a global survey; survey year not stated.[15]
Data Governance in the medical devices sector (sector benchmark)
- More than 30% of healthcare-sector business partners had no clear formal data-governance guidelines in the 2021 survey.[13]
- More than 72% of healthcare-sector business partners had not established a product-master-data system reflecting data governance in the 2021 survey.[13]
- 62.3% of healthcare-sector business partners identified creating a central data master as a single source of truth as the greatest digital-product-information challenge in 2021.[13]
- 31.4% of healthcare-sector business partners had a digital-asset-management system for storing images and product data sheets in the 2021 survey.[13]
06 Statistics
Strategy & Growth
This section anchors demand, applications, and forecast sizing. It reports socket preservation at 30.5% of global application share in 2025 and market growth from $973.1 million in 2026 to $1.7849 billion in 2033.
Growth in the dental bone graft industry
- The global dental bone grafts and substitutes market was valued at $901.1 million in 2025.[16]
- Dentsply Sirona’s End-Use and Equipment segment, which includes dental bone graft materials, grew 28.7% in 2021.[16]
- The U.S. dental bone graft market is projected to grow at a 7.6% CAGR from 2026 to 2035.[17]
- Socket preservation held 30.5% of the global dental bone grafts and substitutes market by application in 2025.[16]
- The global dental bone grafts and substitutes market is projected to reach $1.7849 billion by 2033.[16]
- The global dental bone grafts and substitutes market is estimated at $973.1 million for 2026.[16]
Differentiation in the dental bone graft industry
- Ridge augmentation held a 44.0% share of the U.S. dental bone graft market by application in 2025.[17]
- Socket preservation represented 9% of the U.S. dental bone grafts and substitutes market in 2025.[18]
- Dental implant placement represented 42% of the U.S. dental bone grafts and substitutes market in 2025.[18]
- Xenografts held a 48.2% share of the global dental bone graft market in 2024.[19]
- The U.S. allograft dental bone graft segment is projected to achieve a 9.8% CAGR during the forecast period.[16]
- Xenografts held a 38.0% share of the U.S. dental bone graft market in 2025.[17]
Mergers and acquisitions in the dental bone graft industry
- Henry Schein acquired a 57% voting equity interest in Biotech Dental for preliminary consideration of $423 million in 2023.[20]
- Xtant Medical had previously acquired nanOss distribution rights and intellectual property through its August 2023 acquisition of Surgalign assets.[20]
- IsoTis sold its dental business to Keystone Dental for $7.4 million in 2006.[20]
- Xtant Medical acquired RTI Surgical’s nanOss production operations for $2 million in cash plus contingent royalties in 2023.[20]
Strategic partnerships in the dental bone graft industry
- IsoTis and Keystone Dental entered a five-year manufacturing and supply agreement in 2006.[20]
- Celularity signed an exclusive commercialization agreement with BioCellgraft in December 2023 to manufacture private-label biomaterials for dental and oral healthcare.[20]
- Bone Biologics acquired exclusive U.S. marketing, sales and distribution rights for OsStic under a five-year licensing agreement in 2025.[20]
- Tutogen appointed Sulzer Calcitek as exclusive worldwide distributor of its dental xenograft bone tissue products in 2006.[20]
- BioCellgraft was to distribute Celularity-manufactured advanced biomaterials under private-label brands for dental applications under the 2023 agreement.[20]
07 Statistics
People & Workforce
This section frames workforce cost and operating patterns using remote and hybrid benchmarks. It reports remote employees working 41.5 hours per week in 2023 and median hybrid salary of $135,000.
Remote Work in the medical devices sector (sector benchmark)
- Remote medical device and diagnostics professionals reported a median salary of $142,000 in 2023, according to an industry salary survey.[21]
- Remote medical device and diagnostics employees worked an average of 41.5 hours per week in 2023, compared with 43 hours for office-based employees.[21]
- Remote medical device and diagnostics professionals reported a median 4% pay increase in 2023, according to an industry salary survey.[21]
- About 50% of medical device and diagnostics professionals worked fully remotely in 2023, based on 226 usable survey responses in the United States.[21]
Hybrid Work in the medical devices sector (sector benchmark)
- Hybrid medical device and diagnostics professionals represented about 40% of respondents in MD+DI’s 2023 salary survey, covering 226 usable responses.[21]
- Hybrid medical device and diagnostics professionals reported a median salary of $135,000 in 2023, according to an industry salary survey.[21]
- Hybrid medical device and diagnostics professionals reported a median 4% pay increase in 2023, according to an industry salary survey.[21]
- Hybrid medical device professionals reported a median salary of $150,000 in 2026, compared with $140,000 for remote and $116,000 for in-office professionals.[21]
Employee Engagement in the medical devices sector (sector benchmark)
- In medical devices, 91% of employees agreed they understood how their work contributed to company goals in benchmark data collected through June 2026.[22]
- In medical devices, 73% of employees were engaged in benchmark data collected from July 2025 through June 2026, predominantly across Northern America, Oceania, Europe and Asia.[22]
- Medical devices organizations had a median employee net promoter score of 14 in Culture Amp’s 2026 benchmark.[22]
- In medical devices, 23% of employees disagreed that their total compensation was fair relative to similar roles at other companies in the 2026 benchmark.[22]
Change Management in the medical devices sector (sector benchmark)
- Only 2% of surveyed medical device manufacturers rated their ability to estimate product-change costs as excellent, while 10% rated it poor.[23]
- Among post-market medical device companies surveyed in 2023, 37% cited resistance to change efforts as a challenge to improving quality management processes.[14]
- Among pre-market medical device companies surveyed in 2023, 18% cited lack of management buy-in as a challenge to improving quality management processes.[14]
- Among pre-market medical device companies surveyed in 2023, 25% cited resistance to change efforts as a quality-management challenge.[14]
- Among post-market medical device companies surveyed in 2023, 23% cited lack of management buy-in as a challenge to improving quality management processes.[14]
08 Statistics
Customer & Sales
This section quantifies patient acceptance and willingness to pay to avoid graft surgery. It reports 72% willing to pay extra for guided implant surgery and 54% accepting bone grafting in 2025.
Customer experience in the dental bone graft industry
- 72% of patients in a 2025 survey were willing to pay extra for guided implant surgery to avoid bone-graft surgery.[24]
- 54% of patients in a 2025 survey accepted undergoing bone grafting to enable dental implant placement.[24]
- High professional and patient satisfaction with dental bone grafts was reported among 183 dentists surveyed in Sobral, Brazil.[25]
- 72% of patients in a 2025 survey preferred bone harvesting from the retromolar region over other autologous sites.[24]
- 67% of Austrian implant patients accepted additional costs for guided implant planning to avoid bone-graft surgery.[25]
09 Statistics
Marketing & Brand
This section captures clinician and periodontist interest signals tied to stem-cell-based grafting content. It also includes Geistlich launch planning of 20 regenerative products across more than 40 countries during 2026.
Marketing in the dental bone graft industry
Digital marketing in the dental bone graft industry
- 8.7% of U.S. periodontists surveyed were interested in receiving information about stem-cell-based bone grafting from other people or channels outside the listed education formats.[28]
- 68.7% of 481 U.S. periodontists surveyed were interested in learning about stem-cell-based bone grafting through online continuing education.[28]
- 3.7% of U.S. periodontists surveyed reported learning about stem-cell-based bone grafting through webinars, online tutorials or forums.[28]
Branding in the dental bone graft industry
- 1st place was held by Geistlich Pharma in the global dental bone-graft substitute market in 2025, according to iData Research.[27]
- 3rd place was held by ZimVie in the global dental bone-graft substitute market in 2025, according to iData Research.[27]
- 2nd place was held by Henry Schein in the global dental bone-graft substitute market in 2025, according to iData Research.[26]
Influencer Marketing in the medical devices sector (sector benchmark)
- 10% of healthcare and pharmaceutical marketers reported that they did not invest in creator or influencer marketing in 2026.[29]
- 8.57 million influencer posts about the health industry were published globally in 2023, across the platforms measured by Sprout Social.[30]
- 50% of healthcare and pharmaceutical marketers had dedicated, growing budgets for creator or influencer marketing in 2026.[29]
- 29% of healthcare and pharmaceutical marketers had dedicated but flat budgets for creator or influencer marketing in 2026.[29]
- 1.07% was the average engagement rate for health-industry influencer posts globally in 2023, across the platforms measured by Sprout Social.[30]
10 Statistics
Operations & Execution
This section uses capacity and outsourcing market figures to set an operational context. It reports Granulab stated capacity of 350 kilograms per year for synthetic bone grafts at its Malaysian facility.
Quality management in the dental bone graft industry
Outsourcing / Offshoring in the medical devices sector (sector benchmark)
- $81.5 billion was the global medtech outsourcing market in 2023, covering contract development and manufacturing organizations (CDMOs).[32]
- 11.4% was the year-over-year growth rate of the global medtech outsourcing market in 2023.[32]
- 335 U.S. medical device contract manufacturers were identified in 2022, up from 314 in the prior registry.[32]
- $26.3 billion was the U.S. medtech CDMO market in 2023, after 12.9% growth from 2022.[32]
- $18.5 billion was the European medtech CDMO market in 2023.[32]
11 Statistics
Finance & Pricing
This section reports pricing ranges drawn from U.S. cost studies, separating autograft, alloplast, and xenograft. It also states global market growth inputs: 9.1% projected CAGR from 2026 to 2033.
Pricing strategy in the dental bone graft industry
- $3,447 was the reported average autograft price in California, United States, in the cited dental bone-grafting cost study.[33]
- $576–$1,375 was the reported U.S. average price range per alloplast dental bone graft in the 2024 cost study.[33]
- $652–$1,575 was the reported U.S. average price range per allograft dental bone graft in the 2024 cost study.[33]
- $2,161–$5,148 was the reported U.S. average price range per autograft dental bone graft in the 2024 cost study.[33]
- $2,439 was the reported average autograft price in Alabama, United States, in the cited dental bone-grafting cost study.[33]
Cost reduction in the dental bone graft industry
- $576–$1,375 was the U.S. average alloplast price range, compared with $2,161–$5,148 for an autograft, in the 2024 dental bone-grafting cost study.[33]
- $549–$1,386 was the U.S. average xenograft price range, compared with $2,161–$5,148 for an autograft, in the 2024 dental bone-grafting cost study.[33]
Financial planning in the dental bone graft industry
- 9.1% was the projected compound annual growth rate for the global dental bone grafts and substitutes market from 2026 to 2033.[16]
- $1.7849 billion was the projected global dental bone grafts and substitutes market size for 2033.[16]
- $973.1 million was the estimated global dental bone grafts and substitutes market size for 2026.[16]
12 Statistics
Product & Service
This section provides evidence and labeling datapoints, including defect geometry and clinical-study scale. It cites Geistlich Bio-Gide labeling evidence for vertical defect lengths up to 5.7 mm.
Product development in the dental bone graft industry
- More than 10 million patients have been treated with Geistlich products, according to the company’s scientific-evidence page.[34]
- 15 clinical studies involving 297 unique patients supported expanded labeling for Geistlich Bio-Gide in extraction-site and alveolar-ridge applications.[35]
- Maxigen’s GingivAid Collagen Bone Graft received Taiwan TFDA approval in 2011, marking the product’s entry into the dental bone-graft medical-supplies market.[36]
- More than 100 universities and leading surgeons have collaborated with Geistlich on developing and testing its dental biomaterials, according to the company’s scientific-evidence page.[34]
- About 1,400 publications validate the efficacy of Geistlich Bio-Oss and Bio-Gide bone-regeneration products, according to Geistlich’s cited publication count.[34]
Product lifecycle in the dental bone graft industry
- A randomized clinical trial enrolled 40 patients to compare new bone formation after 3 and 4 months of HA/β-TCP ridge-preservation treatment.[24]
- Osteogenics reported 25 years of innovation and refinement in dental bone-grafting products on its company history page.[37]
- FDA-reviewed animal testing assessed FG Bone Graft B and its predicate at 4, 8 and 12 weeks for new bone formation and material degradation.[35]
- Geistlich Bio-Gide labeling evidence covered alveolar-ridge defects with average vertical defect lengths up to 5.7 mm and ridge widths up to 18 mm.[35]
- The standardized FDA-reviewed alveolar defects measured 10 mm long, 5 mm wide and 5 mm deep.[35]
Value proposition in the dental bone graft industry
- The global dental bone-grafts and substitutes market is projected to reach $1,784.9 million by 2033.[16]
- The global dental bone-grafts and substitutes market was valued at $901.1 million in 2025, according to Grand View Research.[16]
- North America held a 38.3% share of global dental bone-grafts and substitutes revenue in 2025.[16]
- Xenografts accounted for 46.1% of the dental bone-grafts and substitutes market in 2025, according to Grand View Research.[16]
- Socket preservation represented 30.5% of the dental bone-grafts and substitutes market by application in 2025.[16]
13 Statistics
Sustainability & Ethics
This section reports reported sustainability metrics tied to specific companies and years. It includes Straumann Group renewable electricity at 100% in 2024, including 100% at manufacturing sites.
Sustainability in the dental bone graft industry
- 100% of Straumann Group manufacturing sites used renewable electricity in 2024 globally.[38]
- More than 40 medical missions were conducted by Zimmer Biomet in 2024 for underserved patients worldwide.[39]
- 58% of Zimmer Biomet’s in-scope global network was internally certified under its Zero Waste to Landfill initiative in 2024.[39]
- Over 800 people were employed by Geistlich Pharma worldwide, whose portfolio includes dental bone-regeneration products.[34]
- 13 Dentsply Sirona sites used renewable energy in 2024 globally.[40]
ESG in the dental bone graft industry
- 45% was Dentsply Sirona’s reduction in absolute Scope 1 and 2 greenhouse-gas emissions from its 2019 baseline by 2024.[40]
- 82 was Straumann Group’s employee-engagement score in 2024 globally.[38]
- 26% was Dentsply Sirona’s reduction in absolute water withdrawal from its 2019 baseline by 2024.[40]
- 39% of Straumann Group leadership positions were held by women in 2024 globally.[38]
- 98% was Straumann Group’s global renewable-electricity usage in 2024, including 100% at manufacturing sites.[38]
Ethics in the dental bone graft industry
- 9% was Dentsply Sirona’s increase in employee-resource-group membership in 2024.[40]
- 100% of Zimmer Biomet required third-party compliance check-ins were completed in 2024.[39]
- 16 languages were supported by Zimmer Biomet’s updated Code training course in 2024.[39]
- 190 mentor-mentee pairs were matched by Zimmer Biomet in 2024 for leadership and career development.[39]
- 100% of Zimmer Biomet team members and Board directors completed Code of Business Conduct and Ethics training in 2024 globally.[39]
CSR in the dental bone graft industry
- Nearly 9,000 hours of community volunteering were contributed by Zimmer Biomet employees in 2024.[39]
- 1.1 million more smiles were helped by Straumann Group in 2024 than in 2023, reaching 6.7 million.[38]
- 400,000-plus dental professionals were trained by Straumann Group through educational efforts in 2024.[38]
- Over $1 million was donated by Zimmer Biomet to charitable causes in 2024.[39]
- 155 countries were represented among Dentsply Sirona clinical-education course participants in 2024.[40]
Circular economy in the dental bone graft industry
- 100% recyclable packaging is Dentsply Sirona’s target for 2030 across its dental-products business.[40]
- 63% was Straumann Group’s waste recycling rate in 2024 globally, down from 69% in 2023.[38]
- 21 Zimmer Biomet sites were Zero Waste to Landfill certified in 2024.[39]
- The majority of Straumann Group metal waste was recycled in 2024 across its production operations.[38]
- 77% of Zimmer Biomet solid waste was diverted from landfills in 2024.[39]
Carbon footprint in the dental bone graft industry
- 15% is Zimmer Biomet’s 2030 target for reducing Scope 3 emissions from purchased goods and services from its 2019 baseline.[39]
- 55% is Zimmer Biomet’s 2030 target for reducing absolute Scope 1 and 2 emissions from its 2017 baseline.[39]
- 8,781 tonnes CO2e were Straumann Group Scope 1 emissions in 2024.[38]
- 19% was Straumann Group’s reduction in Scope 1 and 2 emissions from its 2021 base year by 2024.[38]
- 1,432 tonnes CO2e were Straumann Group market-based Scope 2 emissions in 2024.[38]
14 Statistics
Risk, Compliance & Legal
This section quantifies safety, recalls, and compliance readiness constraints. It reports cybersecurity-driven rejection rates of 56% of healthcare organizations in 2026 across the United States, United Kingdom and Germany.
Compliance in the dental bone graft industry
- 0.17 was Dentsply Sirona’s total recordable incident rate in 2024 globally.[40]
- 8 Zimmer Biomet product recalls occurred in 2024, down from 63 in 2017.[39]
- 8 new 510(k) clearances were obtained by Dentsply Sirona in 2024.[40]
- 43 Dentsply Sirona sites were certified to ISO 13485 in 2024.[40]
- 347 active 510(k) clearances were held by Dentsply Sirona across its products and devices in 2024.[40]
Risk Management in the medical devices sector (sector benchmark)
- More than 50% of medical device professionals said they could not document closed-loop traceability in 2024.[41]
- 70% of medical device companies used manual documentation and spreadsheets for risk management during the design process in 2023.[42]
- 33% of medical device company leaders felt very confident in the integrity of risk-analysis data in 2023.[42]
- 35% of medical device professionals cited unclear ownership of risk across the product life cycle as a risk-management challenge in 2024.[41]
- 34% of medical device professionals cited insufficient access to appropriate information during design and development as a risk-management challenge in 2024.[41]
Cybersecurity in the medical devices sector (sector benchmark)
- 56% of healthcare organizations across the United States, United Kingdom and Germany rejected a medical device because of cybersecurity concerns in 2026.[43]
- 84% of healthcare organizations across the United States, United Kingdom and Germany included cybersecurity requirements in medical-device vendor RFPs in 2026.[43]
- 35% of healthcare organizations across the United States, United Kingdom and Germany would not consider a medical device without a software bill of materials in 2026.[43]
- 24% of facilities across the United States, United Kingdom and Germany experienced a cyberattack on a medical device in 2026.[43]
- 80% of facilities attacked across the United States, United Kingdom and Germany reported moderate or significant patient-care impact in 2026.[43]
Data Privacy in the medical devices sector (sector benchmark)
- 47% of medtech respondents identified data privacy and security as a key development challenge for their companies in 2024.[44]
- 86% of medical-device stakeholders considered data security for digital health technologies extremely important in a 2023 survey.[45]
- 64% of respondents rated data security for wearable medical devices extremely important in 2023.[46]
- 30% of respondents rated data security for wearable medical devices very important in 2023.[46]
Crisis Management in the medical devices sector (sector benchmark)
- 61% of pharma, life-sciences, medtech and health organizations had conducted exercises with their crisis-management team in 2020.[47]
- 89% of pharma, life-sciences, medtech and health organizations had established a crisis-management organization in 2020.[47]
- 90% of pharma, life-sciences, medtech and health organizations had formulated a business-continuity-management strategy in 2020.[47]
- 57% of pharma, life-sciences, medtech and health organizations had pandemic planning in place in 2020.[47]
Governance in the dental bone graft industry
- 10 Zimmer Biomet directors were nominated for election at the company’s May 2025 Annual Meeting.[39]
- 94% was Straumann Group’s mean completion rate for sales-compliance e-training across 27 countries in 2024.[38]
- Quarterly reports on ESG risks and programs were received by Zimmer Biomet’s Corporate Governance Committee in 2024.[39]
- 11 directors comprised Zimmer Biomet’s Board as of April 2, 2025.[39]
- 100% of Zimmer Biomet Board directors completed Code of Business Conduct and Ethics training in 2024.[39]
15 Statistics
Globalization & Expansion
This section breaks out regional shares and distribution economics. It reports North America as 38.3% of 2025 global revenue and direct sales at 46% of the U.S. market in 2025.
Globalization in the dental bone graft industry
- Europe accounted for 25.58% of the global dental bone graft substitute market in 2021.[48]
- 52% of Envista’s sales came from North America, 22% from Western Europe, 21% from emerging markets and 5% from other developed markets in 2024.[49]
- North America accounted for 38.3% of global dental bone grafts and substitutes revenue in 2025.[16]
- Asia-Pacific is projected to record a 10.9% CAGR in dental bone grafts and substitutes from 2026 to 2033.[16]
- The U.S. represented 42.0% of the North American dental bone graft market in 2025.[17]
Supplier management in the dental bone graft industry
- Xtant Medical paid $2 million in cash plus a low-single-digit royalty on future sales to acquire RTI’s nanOss synthetic bone graft production operations in 2023.[20]
- Xtant Medical assumed the lease for RTI Surgical’s nanOss production facility in Greenville, North Carolina, as part of the 2023 transaction.[20]
- The nanOss royalty arrangement covered next-generation product sales made before October 23, 2028.[20]
- A five-year manufacturing and supply agreement accompanied IsoTis’s 2006 sale of its dental business and bone graft substitute portfolio to Keystone Dental.[20]
Stakeholder management in the dental bone graft industry
Distribution channels in the dental bone graft industry
- Direct sales accounted for 46% of the U.S. dental bone grafts and substitutes market in 2025.[18]
- Dental distributors accounted for 34% of the U.S. dental bone grafts and substitutes market in 2025.[18]
- Online procurement platforms represented 8% of the U.S. dental bone grafts and substitutes market in 2025.[18]
- Online procurement platforms are projected to grow at an 11.2% CAGR in the U.S. dental bone grafts and substitutes market.[18]
- A 2025 licensing agreement gave Bone Biologics exclusive U.S. marketing, sales and distribution rights for OsStic for an initial five-year term.[20]
Key questions about the dental bone graft industry
What is the global market size for dental bone grafts and substitutes in 2025 and 2026?
How fast is the market expected to grow from 2026 to 2033?
Which companies lead the dental bone graft industry?
What technology shifts are being reported in medtech manufacturing and quality systems?
How is the market structured by end user and regional share?
What regulatory frame applies to dental bone grafting material devices in the U.S.?
Cite This Report
This report is designed to be cited. We maintain stable URLs and versioned verification dates. Copy the format appropriate for your publication below.
Samuel Norberg. (2026, November 11). Dental Bone Graft Industry Statistics. Gitnux. https://gitnux.org/dental-bone-graft-industry-statistics
Samuel Norberg. "Dental Bone Graft Industry Statistics." Gitnux, 11 Nov 2026, https://gitnux.org/dental-bone-graft-industry-statistics.
Samuel Norberg. 2026. "Dental Bone Graft Industry Statistics." Gitnux. https://gitnux.org/dental-bone-graft-industry-statistics.
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