GITNUX MARKETDATA REPORT 2024

Proteinuria Survival Statistics

Proteinuria is associated with a higher risk of mortality, especially in patients with chronic kidney disease.

With sources from: karger.com, care.diabetesjournals.org, academic.oup.com, cjasn.asnjournals.org and many more

Statistic 1

Proteinuria is independently associated with a 60% increased risk of mortality among men, and proteinuria combined with reduced eGFR is associated with more than 10-fold higher mortality risk.

Statistic 2

At the end of 1 year, the survival rate for patients with nephrotic syndrome with proteinuria was found to be around 87%.

Statistic 3

CKD patients having proteinuria greater than or equal to 300 mg/g had a 15% increased risk for cardiovascular mortality.

Statistic 4

Survival rate for people with proteinuria after 5 years was 92.2% as observed in a Chinese multi-center study.

Statistic 5

Rapid reduction of proteinuria by more than 50% in 6 months shows improved survival rates in CKD patients.

Statistic 6

The 1-year case fatality rate for patients with nephrotic syndrome with heavy proteinuria was 13%.

Statistic 7

At moderate levels (proteinuria between 30-300 mg/day), risk of End-stage renal disease incidence was 13.2%.

Statistic 8

Massive proteinuria, defined as greater than 10 grams per day, corresponds to a relative risk of 4.1 for death.

Statistic 9

15-year Mortality is 67% higher in patients with proteinuria compared to those without.

Statistic 10

50% of proteinuric patients die within 10 years if on dialysis.

Statistic 11

79.5% of patients survive 2 years after renal biopsy if they have proteinuria less than 1g/day.

Statistic 12

Patients with hypertension and proteinuria have a 2-3 times higher risk of progressing to ESRD.

Statistic 13

92.6% of patients survive 5 years after proteinuria is detected.

Statistic 14

The presence of proteinuria increased the risk of death by 57% in patients with heart failure.

Statistic 15

The survival rate decreases to 50% when the duration of proteinuria is longer than 10 years.

Statistic 16

The 5 year survival rate for nephrotic syndrome patients with heavy proteinuria was 70.9%.

Statistic 17

Proteinuria of 1g/day or greater in T2DM patients increases the risk of ESRD development by 2.83 times.

Statistic 18

In patients with IgA nephropathy, 10-year renal survival rates vary from 88% in patients with minimal proteinuria (<1g/day), to 53% for those with heavy proteinuria (>3.5g/day).

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In this post, we present a comprehensive overview of the significant impact of proteinuria on survival outcomes in various patient populations. Ranging from increased mortality risks to implications for cardiovascular health and renal prognosis, the statistics outlined here shed light on the critical role proteinuria plays in patient outcomes across different conditions. Through an examination of key data points and findings, we aim to underscore the importance of early detection and management strategies in mitigating the adverse effects associated with proteinuria.

Statistic 1

"Proteinuria is independently associated with a 60% increased risk of mortality among men, and proteinuria combined with reduced eGFR is associated with more than 10-fold higher mortality risk."

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Statistic 2

"At the end of 1 year, the survival rate for patients with nephrotic syndrome with proteinuria was found to be around 87%."

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Statistic 3

"CKD patients having proteinuria greater than or equal to 300 mg/g had a 15% increased risk for cardiovascular mortality."

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Statistic 4

"Survival rate for people with proteinuria after 5 years was 92.2% as observed in a Chinese multi-center study."

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Statistic 5

"Rapid reduction of proteinuria by more than 50% in 6 months shows improved survival rates in CKD patients."

Sources Icon

Statistic 6

"The 1-year case fatality rate for patients with nephrotic syndrome with heavy proteinuria was 13%."

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Statistic 7

"At moderate levels (proteinuria between 30-300 mg/day), risk of End-stage renal disease incidence was 13.2%."

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Statistic 8

"Massive proteinuria, defined as greater than 10 grams per day, corresponds to a relative risk of 4.1 for death."

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Statistic 9

"15-year Mortality is 67% higher in patients with proteinuria compared to those without."

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Statistic 10

"50% of proteinuric patients die within 10 years if on dialysis."

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Statistic 11

"79.5% of patients survive 2 years after renal biopsy if they have proteinuria less than 1g/day."

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Statistic 12

"Patients with hypertension and proteinuria have a 2-3 times higher risk of progressing to ESRD."

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Statistic 13

"92.6% of patients survive 5 years after proteinuria is detected."

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Statistic 14

"The presence of proteinuria increased the risk of death by 57% in patients with heart failure."

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Statistic 15

"The survival rate decreases to 50% when the duration of proteinuria is longer than 10 years."

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Statistic 16

"The 5 year survival rate for nephrotic syndrome patients with heavy proteinuria was 70.9%."

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Statistic 17

"Proteinuria of 1g/day or greater in T2DM patients increases the risk of ESRD development by 2.83 times."

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Statistic 18

"In patients with IgA nephropathy, 10-year renal survival rates vary from 88% in patients with minimal proteinuria (<1g/day), to 53% for those with heavy proteinuria (>3.5g/day)."

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Interpretation

Proteinuria has been consistently shown to be a significant predictor of mortality and adverse outcomes in various patient populations. The presence of proteinuria, especially when combined with other risk factors such as reduced eGFR or specific conditions like nephrotic syndrome, is associated with a substantially higher risk of mortality and progression to end-stage renal disease. Rapid reduction of proteinuria appears to improve survival rates in chronic kidney disease patients, highlighting the importance of timely intervention. Additionally, the duration and severity of proteinuria play a crucial role in determining long-term outcomes, with implications for cardiovascular and overall mortality. These statistics underscore the critical need for early detection and management of proteinuria to mitigate its impact on patient survival and quality of life.

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