GITNUX REPORT 2024

Worlds Most Expensive Microscope: Cutting-Edge Technology at $7M

Discover the impressive features and jaw-dropping price tag of the worlds most expensive microscope.

Author: Jannik Lindner

First published: 7/17/2024

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The Titan Krios microscope can perform energy-filtered imaging with an optional energy filter

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The Titan Krios microscope can perform tomography with a tilt range of ±70 degrees

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The Titan Krios microscope can perform in-situ experiments with optional holders

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The Titan Krios microscope can perform single particle analysis with sub-2 Angstrom resolution

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The Titan Krios microscope can perform cryo-electron tomography with a resolution of 3-4 nanometers

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The Titan Krios microscope can perform automated particle picking for single particle analysis

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The Titan Krios microscope can perform automated focus and astigmatism correction

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The Titan Krios microscope can perform automated data collection for up to 5,000 micrographs per day

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The Titan Krios microscope can perform automated tilt series acquisition for tomography

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The Titan Krios microscope can perform automated grid screening and mapping

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The Titan Krios microscope can perform automated data processing and 3D reconstruction

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The Titan Krios microscope can perform automated image acquisition at up to 40 frames per second

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The Titan Krios microscope can perform automated tilt series acquisition with a range of ±70 degrees

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The Titan Krios microscope can perform automated focus gradient correction

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The Titan Krios microscope can accommodate up to 12 sample grids at once

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The most expensive microscope in the world is the Titan Krios cryo-electron microscope, costing around $7 million

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The Titan Krios microscope requires a dedicated room of at least 25 square meters (269 square feet)

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The Titan Krios microscope consumes approximately 5 kW of power during operation

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The Titan Krios microscope can achieve a resolution of 0.15 nanometers

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The Titan Krios microscope can operate at accelerating voltages of 80, 200, or 300 kV

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The Titan Krios microscope can perform automated data collection for up to 72 hours

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The Titan Krios microscope can achieve a magnification range of 25x to 1,000,000x

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The Titan Krios microscope can achieve a point resolution of 0.12 nanometers

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The Titan Krios microscope can achieve an information limit of 0.06 nanometers

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The Titan Krios microscope can achieve an energy resolution of 0.2 eV with a monochromator

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The Titan Krios microscope can achieve a vacuum level of 10^-8 Pa in the specimen chamber

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The Titan Krios microscope can achieve a beam current stability of 0.5% per hour

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The Titan Krios microscope can achieve a temperature stability of ±0.1°C at the sample

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The Titan Krios microscope can achieve a chromatic aberration coefficient of 1.4 mm

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The Titan Krios microscope can achieve a drift rate of less than 0.1 nm per minute

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The Titan Krios microscope can achieve a dose rate of up to 200 e-/Ų/s

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The Titan Krios microscope can achieve a stage drift of less than 0.5 nm per minute at liquid nitrogen temperature

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The Titan Krios microscope can achieve a sample exchange time of less than 1 minute

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The Titan Krios microscope can achieve a sample vitrification time of less than 1 millisecond

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The Titan Krios microscope weighs approximately 4,500 kg (9,920 lbs)

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The Titan Krios microscope stands at about 3 meters (9.8 feet) tall

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The Titan Krios microscope uses liquid nitrogen to cool samples to -196°C (-320.8°F)

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The Titan Krios microscope uses a 4k x 4k CCD camera for image acquisition

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The Titan Krios microscope uses a Field Emission Gun (FEG) as its electron source

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The Titan Krios microscope uses a three-condenser lens system for improved illumination

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The Titan Krios microscope uses a constant power lens design for improved stability

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The Titan Krios microscope uses a piezo-driven stage for precise sample positioning

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The Titan Krios microscope uses a symmetric S-TWIN objective lens for improved resolution

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The Titan Krios microscope uses an advanced auto-loader system for sample exchange

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The Titan Krios microscope uses a Cs-corrector for improved image quality

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The Titan Krios microscope uses a phase plate for improved contrast in biological samples

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The Titan Krios microscope uses a monochromator for improved energy resolution

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The Titan Krios microscope uses a direct electron detector for improved signal-to-noise ratio

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The Titan Krios microscope uses an advanced vacuum system to maintain ultra-high vacuum conditions

Statistic 50

The Titan Krios microscope uses a low-dose imaging mode to minimize sample damage

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The Titan Krios microscope uses a constant current lens design for improved stability

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The Titan Krios microscope uses an advanced image processing software for data analysis

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The Titan Krios microscope uses a cryo-box to maintain sample temperature during transfer

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The Titan Krios microscope uses a phase contrast transfer function (CTF) correction algorithm

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The Titan Krios microscope uses a spherical aberration corrector for improved resolution

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The Titan Krios microscope uses a Volta phase plate for improved contrast in cryo-EM

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The Titan Krios microscope uses a cryo-transfer system to maintain sample integrity

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The Titan Krios microscope uses a multi-specimen holder for increased throughput

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The Titan Krios microscope uses a cryo-shutter to protect samples from contamination

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The Titan Krios microscope uses a beam blanker to control electron dose

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The Titan Krios microscope uses a cryo-stage for maintaining sample temperature during imaging

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The Titan Krios microscope uses a fast camera for improved data collection speed

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The Titan Krios microscope uses a cryo-autoloader for automated sample exchange

Statistic 64

The Titan Krios microscope uses a dual-axis tomography holder for improved 3D reconstruction

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The Titan Krios microscope uses a cryo-plunging device for sample preparation

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The Titan Krios microscope uses a phase plate for improved contrast in low-dose imaging

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Summary

  • The most expensive microscope in the world is the Titan Krios cryo-electron microscope, costing around $7 million
  • The Titan Krios microscope weighs approximately 4,500 kg (9,920 lbs)
  • The Titan Krios microscope stands at about 3 meters (9.8 feet) tall
  • The Titan Krios microscope can achieve a resolution of 0.15 nanometers
  • The Titan Krios microscope uses liquid nitrogen to cool samples to -196°C (-320.8°F)
  • The Titan Krios microscope can operate at accelerating voltages of 80, 200, or 300 kV
  • The Titan Krios microscope uses a 4k x 4k CCD camera for image acquisition
  • The Titan Krios microscope can accommodate up to 12 sample grids at once
  • The Titan Krios microscope uses a Field Emission Gun (FEG) as its electron source
  • The Titan Krios microscope can perform automated data collection for up to 72 hours
  • The Titan Krios microscope requires a dedicated room of at least 25 square meters (269 square feet)
  • The Titan Krios microscope consumes approximately 5 kW of power during operation
  • The Titan Krios microscope uses a three-condenser lens system for improved illumination
  • The Titan Krios microscope can achieve a magnification range of 25x to 1,000,000x
  • The Titan Krios microscope uses a constant power lens design for improved stability

Step right up, folks, and behold the marvel that is the Titan Krios cryo-electron microscope – the Ferrari of scientific instruments, priced at a cool $7 million. Weighing as much as a herd of elephants, towering taller than a basketball star, and capable of capturing images at a mind-boggling 0.15 nanometer resolution, this behemoth not only pushes the boundaries of technology but also gives new meaning to the phrase big things come in small packages. So strap in, because were about to take a rollercoaster ride through the fantastical world of the most expensive microscope in existence, where liquid nitrogen flows like champagne and precision is the name of the game. Get ready to be amazed, astonished, and perhaps a tad envious, as we uncover the secrets behind the Titan Krios and its larger-than-life capabilities.

Capabilities

  • The Titan Krios microscope can perform energy-filtered imaging with an optional energy filter
  • The Titan Krios microscope can perform tomography with a tilt range of ±70 degrees
  • The Titan Krios microscope can perform in-situ experiments with optional holders
  • The Titan Krios microscope can perform single particle analysis with sub-2 Angstrom resolution
  • The Titan Krios microscope can perform cryo-electron tomography with a resolution of 3-4 nanometers
  • The Titan Krios microscope can perform automated particle picking for single particle analysis
  • The Titan Krios microscope can perform automated focus and astigmatism correction
  • The Titan Krios microscope can perform automated data collection for up to 5,000 micrographs per day
  • The Titan Krios microscope can perform automated tilt series acquisition for tomography
  • The Titan Krios microscope can perform automated grid screening and mapping
  • The Titan Krios microscope can perform automated data processing and 3D reconstruction
  • The Titan Krios microscope can perform automated image acquisition at up to 40 frames per second
  • The Titan Krios microscope can perform automated tilt series acquisition with a range of ±70 degrees
  • The Titan Krios microscope can perform automated focus gradient correction

Interpretation

The Most Expensive Microscope, the Titan Krios, is not just a piece of equipment—it's the James Bond of microscopy. With its ability to perform a myriad of mind-blowing tasks like energy-filtered imaging, in-situ experiments, and single particle analysis with sub-2 Angstrom resolution, this microscope is essentially a high-tech Swiss Army knife for scientists. It's like having a personal assistant that can pick up 5,000 micrographs a day, do tilt series acquisition with a range of ±70 degrees, and even handle focus and astigmatism correction like a pro. Move over, Avengers, the Titan Krios is here to save the day—one nanometer at a time.

Capacity

  • The Titan Krios microscope can accommodate up to 12 sample grids at once

Interpretation

The Titan Krios microscope's ability to juggle an impressive 12 sample grids at once is a true testament to its multitasking prowess. While most of us struggle to handle just one task at a time, the Titan Krios fearlessly takes on a dozen, all while delivering groundbreaking insights at the nanoscale level. Who knew that the world of microscopy could be such a high-stakes balancing act?

Cost

  • The most expensive microscope in the world is the Titan Krios cryo-electron microscope, costing around $7 million

Interpretation

In a world where diamonds may be considered a girl's best friend, the Titan Krios cryo-electron microscope shines as a scientist's ultimate companion, with a price tag that would make even the most extravagant gemstone blush. At a jaw-dropping $7 million, this microscope isn't just a tool for magnifying the tiniest of details—it's a status symbol of cutting-edge research and technological prowess. With the power to unravel mysteries at the atomic level, it's no wonder the Titan Krios commands a price that could make any budget-conscious researcher break out in a cold sweat.

Installation Requirements

  • The Titan Krios microscope requires a dedicated room of at least 25 square meters (269 square feet)
  • The Titan Krios microscope consumes approximately 5 kW of power during operation

Interpretation

The staggering size of the dedicated room for the Titan Krios microscope could easily accommodate a small family of four and their pet dog, providing new meaning to the concept of giving space to your equipment. Meanwhile, with its impressive appetite for power, one can only imagine the microscope sending other devices on a citywide power outage alert. In the realm of scientific research, where every detail counts, the Titan Krios certainly commands attention - and electricity bills.

Performance

  • The Titan Krios microscope can achieve a resolution of 0.15 nanometers
  • The Titan Krios microscope can operate at accelerating voltages of 80, 200, or 300 kV
  • The Titan Krios microscope can perform automated data collection for up to 72 hours
  • The Titan Krios microscope can achieve a magnification range of 25x to 1,000,000x
  • The Titan Krios microscope can achieve a point resolution of 0.12 nanometers
  • The Titan Krios microscope can achieve an information limit of 0.06 nanometers
  • The Titan Krios microscope can achieve an energy resolution of 0.2 eV with a monochromator
  • The Titan Krios microscope can achieve a vacuum level of 10^-8 Pa in the specimen chamber
  • The Titan Krios microscope can achieve a beam current stability of 0.5% per hour
  • The Titan Krios microscope can achieve a temperature stability of ±0.1°C at the sample
  • The Titan Krios microscope can achieve a chromatic aberration coefficient of 1.4 mm
  • The Titan Krios microscope can achieve a drift rate of less than 0.1 nm per minute
  • The Titan Krios microscope can achieve a dose rate of up to 200 e-/Ų/s
  • The Titan Krios microscope can achieve a stage drift of less than 0.5 nm per minute at liquid nitrogen temperature
  • The Titan Krios microscope can achieve a sample exchange time of less than 1 minute
  • The Titan Krios microscope can achieve a sample vitrification time of less than 1 millisecond

Interpretation

The Titan Krios microscope is not just another pretty piece of equipment; it's the superhero of the microscopy world, armed with the power to see things at an atomic level that would make other microscopes green with envy. With its ability to achieve mind-boggling resolutions and magnifications, operate for extended periods autonomously, and maintain stability akin to a yogi on a mountaintop, this microscope is more than just a tool—it's a legend in the scientific community. So, move over mere mortal microscopes, the Titan Krios has arrived, ready to reveal the hidden secrets of the infinitesimally small with style and precision.

Physical Specifications

  • The Titan Krios microscope weighs approximately 4,500 kg (9,920 lbs)
  • The Titan Krios microscope stands at about 3 meters (9.8 feet) tall

Interpretation

The impressive Titan Krios microscope, weighing as much as a small elephant and towering over the average human, seems to defy the laws of physics with its hefty presence in the scientific world. With a weight that could make even gym enthusiasts break a sweat and a height that rivals some NBA players, this powerhouse of a microscope surely packs a punch in both its literal and figurative weight in groundbreaking research. The Titan Krios isn't just a microscope; it's a force to be reckoned with, showcasing that when it comes to scientific exploration, size does matter.

Technology

  • The Titan Krios microscope uses liquid nitrogen to cool samples to -196°C (-320.8°F)
  • The Titan Krios microscope uses a 4k x 4k CCD camera for image acquisition
  • The Titan Krios microscope uses a Field Emission Gun (FEG) as its electron source
  • The Titan Krios microscope uses a three-condenser lens system for improved illumination
  • The Titan Krios microscope uses a constant power lens design for improved stability
  • The Titan Krios microscope uses a piezo-driven stage for precise sample positioning
  • The Titan Krios microscope uses a symmetric S-TWIN objective lens for improved resolution
  • The Titan Krios microscope uses an advanced auto-loader system for sample exchange
  • The Titan Krios microscope uses a Cs-corrector for improved image quality
  • The Titan Krios microscope uses a phase plate for improved contrast in biological samples
  • The Titan Krios microscope uses a monochromator for improved energy resolution
  • The Titan Krios microscope uses a direct electron detector for improved signal-to-noise ratio
  • The Titan Krios microscope uses an advanced vacuum system to maintain ultra-high vacuum conditions
  • The Titan Krios microscope uses a low-dose imaging mode to minimize sample damage
  • The Titan Krios microscope uses a constant current lens design for improved stability
  • The Titan Krios microscope uses an advanced image processing software for data analysis
  • The Titan Krios microscope uses a cryo-box to maintain sample temperature during transfer
  • The Titan Krios microscope uses a phase contrast transfer function (CTF) correction algorithm
  • The Titan Krios microscope uses a spherical aberration corrector for improved resolution
  • The Titan Krios microscope uses a Volta phase plate for improved contrast in cryo-EM
  • The Titan Krios microscope uses a cryo-transfer system to maintain sample integrity
  • The Titan Krios microscope uses a multi-specimen holder for increased throughput
  • The Titan Krios microscope uses a cryo-shutter to protect samples from contamination
  • The Titan Krios microscope uses a beam blanker to control electron dose
  • The Titan Krios microscope uses a cryo-stage for maintaining sample temperature during imaging
  • The Titan Krios microscope uses a fast camera for improved data collection speed
  • The Titan Krios microscope uses a cryo-autoloader for automated sample exchange
  • The Titan Krios microscope uses a dual-axis tomography holder for improved 3D reconstruction
  • The Titan Krios microscope uses a cryo-plunging device for sample preparation
  • The Titan Krios microscope uses a phase plate for improved contrast in low-dose imaging

Interpretation

The Titan Krios microscope may sound like a high-tech superhero with its liquid nitrogen-cooled samples and array of advanced features, but in the world of microscopy, it's the real deal. From its cryo-cooling capabilities to its cutting-edge imaging technologies, the Titan Krios is not just a microscope – it's a powerhouse of scientific precision and innovation. With its ability to maintain ultra-high vacuum conditions and minimize sample damage, this microscope is not just seeing the tiny world around us, it's reshaping our understanding of it with crystal clear resolution and contrast. Just remember, with great power comes great magnification!

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